Fractional CO2 Laser Treatment after Transvaginal Polypropilene Mesh for Urinary Incontinence and Pelvic Organ Prolapse Treatment as an Alternative to Improove Mesh Erosion Rates

The support advantages of synthetic mesh in vaginal reconstructive surgery and stress urinary incontinence are significant. However, erosion of the mesh may occur as a complication, Four sessions of fractional CO2 Laser treatment protocol (Mona Lisa Touch Deka M.E.L.A Florence Italy protocol, were performed in the study group to 96 patients, beginning at 30 days, after mesh insertion, important improvement regarding erosion rates was found inside our study group, thanks to the trophic effects of fractional CO2 laser protocol. The use of alternative technologies that provide bio -stimulation of vaginal epithelium by increasing its thickness, and trophic changes that may be related to the very low erosion rate was found in our group of patients

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The beneficial effects of fractional CO2 laser treatment on perineal changes during puerperium and breastfeeding period: a multicentric study

Lasers in Medical Science ◽

10.1007/s10103-020-03212-x ◽

2021 ◽

Author(s):

Daniela Luvero ◽

Maurizio Filippini ◽

Stefano Salvatore ◽

Annalisa Pieralli ◽

Miriam Farinelli ◽

...

Keyword(s):

Laser Treatment ◽

Co2 Laser ◽

Multicentric Study ◽

Fractional Co2 Laser ◽

Beneficial Effects ◽

Co2 Laser Treatment

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Early Regenerative Modifications of Human Postmenopausal Atrophic Vaginal Mucosa Following Fractional CO2 Laser Treatment

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2018.058 ◽

2018 ◽

Vol 6 (1) ◽

pp. 6-14 ◽

Cited By ~ 14

Author(s):

Stefano Salvatore ◽

Katlein França ◽

Torello Lotti ◽

Marta Parma ◽

Sonia Palmieri ◽

...

Keyword(s):

Connective Tissue ◽

Laser Treatment ◽

Co2 Laser ◽

Vaginal Mucosa ◽

Structural Components ◽

Related Factors ◽

Fractional Co2 Laser ◽

Collagen Iii ◽

Co2 Laser Treatment ◽

Stimulation Of

BACKGROUND: Postmenopausal women experience undesired symptoms that adversely affect their quality of life. In the recent years, a specific 12 - week fractional CO2 laser treatment has been introduced, with highly significant relief of symptoms.AIM: The aim of this paper is the identification of the early modifications of structural components of atrophic vaginal mucosa induced by laser irradiation, which is responsible for the restorative processes.MATERIAL AND METHODS: We investigated by microscopical, ultrastructural and biochemical methods the modifications of the structural components of postmenopausal atrophic vaginal mucosa tissues after 1 hour following a single fractional laser CO2 application.RESULTS: In one hour, the mucosal epithelium thickens, with the maturation of epithelial cells and desquamation at the epithelial surface. In the connective tissue, new papillae indenting the epithelium with newly formed vessels penetrating them, new thin fibrils of collagen III are also formed in a renewed turnover of components due to the increase of metalloproteinase - 2. Specific features of fibroblasts support stimulation of their activity responsible of the renewal of the extracellular matrix, with an increase of mechanical support as connective tissue and stimulation of growth and maturation to epithelium thanks to new vessels and related factors delivered.CONCLUSION: We found the activation of regenerative mechanisms expressed both in the connective tissue - with the formation of new vessels, new papillae, and new collagen - and in the epithelium with the associated thickening and desquamation of cells at the mucosal surface.

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