scholarly journals Nicolau syndrome

2021 ◽  
Vol 1 ◽  
pp. 30
Author(s):  
Suggu Sriram ◽  
Ankita Tuknayat
Keyword(s):  

Author(s):  
Harris I Shaafie ◽  
Soumya Agarwal ◽  
Swosti Mohanty ◽  
Chandni Jain

Nicolau syndrome (NS) is a rare complication characterized by tissue necrosis that occurs after parenteral injection of drugs. The exact pathogenesis is uncertain, but there are several hypotheses, including direct damage to the end artery, acute vasospasm and cytotoxic effects of the drug. Severe pain in the immediate post injection period and purplish discoloration of the skin with reticulate pigmentary pattern is characteristic of this syndrome. Diagnosis is mainly clinical and there is no standard treatment for the disease. Herein, we present a rare case of NS due to Diclofenac Sodium (Voltaren®) injection in an 80-year-old female suffering from Lower Respiratory Tract Infection (LRTI) who was managed conservatively. Keywords: Nicolau Syndrome, Embolia cutis medicamentosa, Voltaren, Diclofenac sodium



2014 ◽  
Vol 8 (1) ◽  
Author(s):  
İnci Kılıç ◽  
Füruzan Kaya ◽  
Ayşe T Özdemir ◽  
Tuğba Demirel ◽  
İlhami Çelik


2016 ◽  
Vol 15 (1) ◽  
pp. 70-73 ◽  
Author(s):  
Carlos Alberto Araujo Chagas ◽  
Tulio Fabiano de Oliveira Leite ◽  
Lucas Alves Sarmento Pires

Abstract We report on the case of a 40-year-old male who was admitted to the clinic with a large ulcer on his left buttock, 3 days after an intramuscular benzathine penicillin injection. The patient was diagnosed with Nicolau syndrome, a rare vascular complication in which a lesion develops after intramuscular injection. Symptoms are intense pain at the injection site, erythema, and livedoid dermatitis, which leads to necrosis of skin, subcutaneous tissue and muscle tissue. It was described by Nicolau after intramuscular injections of bismuth salt for syphillis therapy. Nicolau syndrome is rare, but its symptoms are devastating and healthcare professionals must be aware of this clinical entity, since intramuscular injections are common procedures for administration of drugs.



2018 ◽  
Vol 40 (3) ◽  
pp. 212-215 ◽  
Author(s):  
Dominic Tabor ◽  
Chandra G. Bertram ◽  
Andrew J. K. Williams ◽  
Marie E. Mathers ◽  
Asok Biswas




2015 ◽  
Vol 50 (4) ◽  
pp. 333
Author(s):  
Seong Jun Ahn ◽  
Suk Woong Kang ◽  
Bu Hwan Kim ◽  
Moo Ho Song ◽  
Seong Ho Yoo ◽  
...  
Keyword(s):  


2021 ◽  
Vol 64 ◽  
pp. 101597
Author(s):  
Yapo Guy serge Kouamé ◽  
Jean Baptiste Yaokreh ◽  
Moufidath Sounkeré ◽  
Samba Tembely ◽  
Idalia Taguela Ajoumissi ◽  
...  


Vaccine ◽  
2012 ◽  
Vol 30 (11) ◽  
pp. 2035-2036 ◽  
Author(s):  
Philippe Bégin ◽  
Des Roches Anne


2020 ◽  
Vol 7 (1) ◽  
pp. 88-93
Author(s):  
Luis de Almeida Maia ◽  
Olga Pereira ◽  
Ricardo Marta ◽  
Joana Costa ◽  
Ana Batista ◽  
...  


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