scholarly journals Cerebriform congenital melanocytic nevus of scalp and its management using tissue expansion

2021 ◽  
Vol 0 ◽  
pp. 1-3
Author(s):  
Shruti Patel ◽  
Naveen Kumar
Keyword(s):  
Tissue Expansion ◽  
Surgical Excision ◽  
Melanocytic Nevus ◽  
Congenital Melanocytic Nevus ◽  
Parietal Region ◽  
Psychological Consequences ◽  
Tissue Expanders ◽  
Pigmented Lesion ◽  
Scalp Defect ◽  
Variable Surface

Congenital melanocytic nevi are benign proliferations of cutaneous nevomelanocytes. Usually, they manifest at birth or become apparent within the first few years of life. The nevi show variable surface morphology (papular, rugose, verrucous, or cerebriform). Congenital melanocytic nevus showing cerebriform morphology is a rarity. Early diagnosis and surgical excision are usually recommended in congenital melanocytic nevus to prevent the future risk of malignant transformation which is higher in larger lesions, especially in giant forms (>20 cm in size). An excision of the lesion also helps to avoid the social and psychological consequences arising out of significant cosmetic deformity. We report a 21-year-old patient who presented with a cerebriform congenital melanocytic nevus measuring 10 cm × 7 cm × 2 cm in the right parietal region. Early-onset, pigmented lesion with a cerebriform surface, and the histopathology features of congenital melanocytic nevus were the points that favored the diagnosis of cerebriform congenital melanocytic nevus in our patient. He was treated with excision of the lesion and defect coverage with tissue expansion in two stages. Two rectangular tissue expanders were placed beneath the galea aponeurotica (one with a capacity of 300 cc in the left parietal region and another with 500 cc in the occipital region). Both the expanders were inflated twice to their capacity. Second stage surgery was performed after about 3 months in which the tissue expanders were removed and the pre-expanded scalp skin was used to drape the scalp defect that resulted from the excision of the lesion. An excision and a two staged reconstruction of the scalp using tissue expanders, may ensure a good aesthetic outcome in the management of intermediate to large sized congenital melanocytic nevus.

scholarly journals Use of Preexpanded Forehead and Neck Skin in Case of Giant Facial Hairy Naevus: Planning and Technique

2020 ◽  
Author(s):  
Mukesh Kumar Sharma ◽  
Naveen Kumar ◽  
V. Suman Babu ◽  
Vinay Kumar Tiwari
Keyword(s):  
Case Report ◽  
Tissue Expansion ◽  
Surgical Excision ◽  
Tissue Expanders ◽  
Pigmented Lesion ◽  
Complete Surgical Excision ◽  
Good Cosmetic ◽  
The Right ◽  
Staged Reconstruction

AbstractA congenital nevi is a pigmented patch which requires complete surgical excision for cosmetic reasons. Here, we report a case of a patient with facial hairy pigmented lesion, occupying the right half of her face since birth, who underwent complete surgical excision and staged reconstruction utilizing, preexpanded forehead and neck skin. We used two rectangular tissue expanders with 150 and 300 cubic cm of volumes inserted in the forehead and the neck, respectively. The length of the expanders selected were equal to 1.2 to 1.5 times the length of their respective lesions, whereas the width of the base of the expanders were approximately similar to the width of their defects. It is concluded with this case report that tissue expansion provides a good cosmetic and anatomical correction to cover large defects, with adjacent skin having similar properties.

scholarly journals Giant Congenital Melanocytic Nevus (GCMN) - A New Hope for Targeted Therapy?

2017 ◽  
Vol 5 (4) ◽  
pp. 549-550 ◽  
Author(s):  
Georgi Tchernev ◽  
Ilia Lozev ◽  
Ivan Pidakev ◽  
Torello Lotti ◽  
Uwe Wollina ◽  
...  
Keyword(s):  
Melanocytic Nevus ◽  
Whole Body ◽  
Occurrence Rate ◽  
Lateral Part ◽  
Congenital Melanocytic Nevus ◽  
Older Children ◽  
Melanocytic Nevi ◽  
Pigmented Lesion ◽  
Surgical Methods ◽  
Congenital Melanocytic Nevi

We present a 6-month-old male patient, who was consulted with dermatologist by his parents, because of a pigmented lesion, present since birth, covering almost the all skin of the back and buttocks.  A sharply bordered, unequally coloured congenital pigmented nevus, measuring approximately 21 cm in diameter was observed in the whole body skin examination. The lesion was affecting the lower 2/3 of the skin of the back and the top half of the gluteus area, extending to the lateral part of the tors, forward the abdomen and the upper lateral part of the hips, composed by multiple darker-pigmented nests and several lighter areas, with single depigmented zones, hairy surface, irregularly infiltrated on palpation. Congenital melanocytic nevi are presented in approximately 1% of newborns, while giant congenital melanocytic nevi (GCMN) are the most uncommon subtype of them; with occurrence rate 1 in 50,000 births. They affect 2% of a total body surface or presenting in a diameter larger than 20 cm in older children. Although not common, the possible malignant transformation remains one of the most important considerations related to them, as the related lifetime risk of melanoma is 4% to 10%. Treatment recommendations include non-surgical methods as dermabrasion only within the first two weeks of life, for prevention the possible melanocytic deeper migration, while serial surgical excisions or tissue expanders could be useful treatment tool even in later stages. Nevertheless, cosmetic result is not always satisfactory, and the risk of malignant changes remains, in cases of previous melanocytic migration in deeper layer. Recent article suggests the potential role in the treatment of GCMN with NRAS inhibitor trametinib, approved for treatment of advanced melanoma, associated with underlying NRAS mutations. Although promising, the drug could be useful in paediatric patients, only with associated NRAS gene mutation. It is still unclear whether it could be helpful, independent of the NRAS status.

scholarly journals Congenital melanocytic nevus of the oral mucosa: report of a rare pigmented lesion and review of the literature

2011 ◽  
Vol 1 (1) ◽  
pp. 17 ◽  
Author(s):  
Melanie Louise Gilbert ◽  
Weddad Hanna ◽  
Danny Ghazarian ◽  
Dean Dover ◽  
Hagen Benjamin Edward Klieb
Keyword(s):  
Oral Mucosa ◽  
Melanocytic Nevus ◽  
Congenital Melanocytic Nevus ◽  
Review Of The Literature ◽  
Melanocytic Nevi ◽  
Pigmented Lesions ◽  
Pigmented Lesion ◽  
Congenital Melanocytic Nevi

Oral pigmented lesions are uncommon and congenital melanocytic nevi are especially rare. We report a case of a patient with multiple congenital melanocytic nevi including a palatal lesion. This is reported to add to the scant literature that exists on this subject. Prognosis and management are discussed.

scholarly journals Tissue expansion in operated cases of transposition flap of scalp for correction of donor site alopecia and patient’s satisfaction

2018 ◽  
Vol 5 (7) ◽  
pp. 2461
Author(s):  
Pradeep Goil ◽  
Abhimanyu Singh ◽  
Hiranmayi Kumari ◽  
Ayush Jain
Keyword(s):  
Donor Site ◽  
Major Complication ◽  
Tissue Expansion ◽  
Transposition Flap ◽  
Tissue Expanders ◽  
Patient’S Satisfaction ◽  
Scalp Defects ◽  
Scalp Defect ◽  
Post Traumatic ◽  
The Mean

Background: Scalp defects managed by local transposition flaps with donor site alopecia are aesthetically not acceptable to patients. Scalp expansion with tissue expanders is needed for proper correction of this deformity.Methods: Authors retrospectively reviewed all cases of post traumatic and post burn scalp defects that were managed initially by local transposition flap and later by scalp expansion by tissue expanders at our institute over a period of 5 years and conducted an outcome survey. Authors’ institutional protocol in such patients and results of the review are presented.Results: Twenty-eight patients were included in the study. Eight patients had post traumatic and 20 cases had post electric burn scalp defect. The mean age of patients was 28.92±8.26 years. Thirty-eight tissue expanders of various sizes (200-600 ml) were used in 28 patients. The mean follow-up time was 9.07±1.92 months. Major complication rate in present study was 2.63%. Results of outcome survey revealed more than 90% patients were satisfied after third surgery.Conclusions: Scalp transposition flap donor site alopecia can be easily corrected by tissue expansion. The complications are not severe and can be managed easily. It should be offered to all such types of patients, as it leads to proper social rehabilitation and satisfaction among these groups of patients.

scholarly journals Congenital Melanocytic Nevus and Fibroepithelioma of Pinkus: A Rare Type of Collision Tumor

2021 ◽  
Vol 19 (1) ◽  
pp. 81-83
Author(s):  
Anil Kumar Bhatta ◽  
Uma Keyal ◽  
Yeqiang Liu 
Keyword(s):  
Collision Tumor ◽  
Melanocytic Nevus ◽  
Melanocytic Lesion ◽  
Congenital Melanocytic Nevus ◽  
Rare Type ◽  
Pigmented Lesion

Congenital melanocytic nevus  is benign pigmented lesion of the skin usually present at birth. Here we report a case of 61-year-old male who presented with a pigmented lesion on the trunk, which on biopsy showed features of both  congenital melanocytic nevus and fibroepithelioma of Pinkus. We reviewed literature for this combination and found only one case reported so far. Hence, it seems that it is very unusual to seefibroepithelioma of Pinkus in conjunction with a melanocytic lesion. 

scholarly journals Late Onset Achromatic Melanoma Arising in a Giant Congenital Melanocytic Nevus

2017 ◽  
Vol 5 (4) ◽  
pp. 533-534 ◽  
Author(s):  
Georgi Tchernev ◽  
James W. Patterson ◽  
Ilko Bakardzhiev ◽  
Torello Lotti ◽  
Jacopo Lotti ◽  
...  
Keyword(s):  
Late Onset ◽  
Surgical Excision ◽  
Melanocytic Nevus ◽  
Secondary Development ◽  
Surgical Removal ◽  
Congenital Melanocytic Nevus ◽  
Melanocytic Nevi ◽  
Giant Congenital Melanocytic Nevi ◽  
Congenital Melanocytic Nevi ◽  
Giant Congenital Melanocytic Nevus

A 61-year-old woman, with a lifelong history of a giant congenital melanocytic nevus in the occipital region with secondary development of giant melanoma is presented. Surgical excision was performed, and the histopathological evaluation confirmed the diagnosis of Giant Malignant Melanoma (GMM) with a maximum tumour thickness of 16 mm. Nowadays, there is tremendous uncertainty regarding how giant congenital melanocytic nevi (GCMN) should be treated. The standard approach to patients with late onset giant congenital melanocytic nevi (GCMN is based on two main considerations: (1) obtain an acceptable cosmetic results with the purpose to decrease the psychosocial inconvenience to each patient, and (2) to attempt to minimise the risk of development of malignant transformation. Unfortunately complete surgical removal of the GCMN is usually difficult and very often impossible without subsequent functional or cosmetic mutilations.

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