scholarly journals Clinical and morphological features of cells implicated in the pathogenesis of idiopathic epiretinal membrane formation in patients with different visual acuity

2017 ◽  
pp. 6-11
Author(s):  
I.M. Gorshkov ◽  
◽  
S.V. Kolesnik ◽  
A.V. Miridonova ◽  
V.I. Shestopalov ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Epiretinal Membrane ◽  
Morphological Features ◽  
Membrane Formation ◽  
Idiopathic Epiretinal Membrane

Natural History of Idiopathic Epiretinal Membrane in Eyes with Good Vision Assessed by Spectral-Domain Optical Coherence Tomography

2015 ◽  
Vol 234 (2) ◽  
pp. 91-100 ◽  
Author(s):  
Ik Soo Byon ◽  
Gang Yun Pak ◽  
Han Jo Kwon ◽  
Kyong Ho Kim ◽  
Sung Who Park ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Natural History ◽  
Visual Function ◽  
Epiretinal Membrane ◽  
Membrane Separation ◽  
Early Stage ◽  
Optical Coherence ◽  
Idiopathic Epiretinal Membrane ◽  
History Of

Purpose: To investigate the natural history of idiopathic epiretinal membrane (ERM) in eyes with good visual function using optical coherence tomography (OCT). Methods: Sixty-two eyes of 58 patients with idiopathic ERM, visual acuity of 20/40 or better, and no significant metamorphopsia were included. The best corrected visual acuity (BCVA), central macular thickness (CMT), membrane configuration, and ellipsoid zone signal data over 24 months were retrospectively analyzed. Based on OCT findings, ERM configurations were categorized as global attachment (GA), partial attachment (PA), pseudohole, and vitreomacular traction (VMT). Results: The mean BCVA and CMT did not change significantly between baseline and 24 months. GA, PA, pseudohole, and VMT types were observed in 33, 19, 9, and 1 eye at baseline, and in 20, 22, 10, and 1 eye at 24 months, respectively. A membrane configuration change was noted in 24 eyes (38.7%) during follow-up, and the distribution shifted from GA to the other types (p < 0.001). Six eyes had visual loss due to membrane progression, and 4 eyes had spontaneous membrane separation. Of the 10 eyes with progression or separation, 6 were of the PA type. Conclusions: Although the BCVA remains stable over 2 years in most idiopathic ERM eyes with good visual function at baseline, the membrane configuration may change, affecting visual acuity. The GA type would be an early stage, and the PA type is prone to changes in visual acuity.

Possible contribution of hyalocytes to idiopathic epiretinal membrane formation and its contraction

2009 ◽  
Vol 93 (8) ◽  
pp. 1020-1026 ◽  
Author(s):  
R-i Kohno ◽  
Y Hata ◽  
S Kawahara ◽  
T Kita ◽  
R Arita ◽  
...  
Keyword(s):  
Epiretinal Membrane ◽  
Membrane Formation ◽  
Idiopathic Epiretinal Membrane

scholarly journals The Thickness of Each Retinal Layer and Visual Acuity after Vitrectomy in Idiopathic Epiretinal Membrane

2017 ◽  
Vol 58 (4) ◽  
pp. 420 ◽  
Author(s):  
Min Hwan Kim ◽  
Chan Yang Jeon ◽  
Seung Kook Baek ◽  
Young Suk Chang ◽  
Young Hoon Lee
Keyword(s):  
Visual Acuity ◽  
Epiretinal Membrane ◽  
Retinal Layer ◽  
Idiopathic Epiretinal Membrane

Inner retinal layer thickness is the major determinant of visual acuity in patients with idiopathic epiretinal membrane

2012 ◽  
Vol 91 (3) ◽  
pp. e242-e243 ◽  
Author(s):  
Soo Geun Joe ◽  
Kyung Sub Lee ◽  
Joo Yong Lee ◽  
Jong-uk Hwang ◽  
June-Gone Kim ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Layer Thickness ◽  
Epiretinal Membrane ◽  
Major Determinant ◽  
Retinal Layer ◽  
Idiopathic Epiretinal Membrane

Optical coherence tomography biomarkers for visual acuity in patients with idiopathic epiretinal membrane

2020 ◽  
pp. 112067212098095
Author(s):  
Evdoxia-Maria Karasavvidou ◽  
Georgios D Panos ◽  
Spyridon Koronis ◽  
Vassilios P Kozobolis ◽  
Paris G Tranos
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Epiretinal Membrane ◽  
Retinal Thickness ◽  
Segment Length ◽  
Inner Plexiform Layer ◽  
Optical Coherence ◽  
Foveal Thickness ◽  
Cotton Ball ◽  
Idiopathic Epiretinal Membrane

Purpose: To investigate the correlation between outer and inner retina optical coherence tomography (OCT) biomarkers and visual acuity in patients with idiopathic epiretinal membrane (iERM) and identify which of them may be predictive of visual function. Methods: A retrospective cross-sectional single-center study was conducted that included patients diagnosed with iERM. Spectral domain OCT images were obtained and assessed qualitatively and quantitatively. The association of OCT parameters with best corrected visual acuity was analyzed. Results: Charts of 97 eyes of 97 patients were reviewed. Central foveal thickness, maximal retinal thickness (MRT), photoreceptor outer segment length, outer foveal thickness, ganglion cell-inner plexiform layer complex thickening, inner retinal thickness and inner retinal layer irregularity index were among the major outcome measures. OCT scans were also assessed for the presence of cotton ball sign, ellipsoid zone disruption, ectopic inner foveal layer, disorganization of retinal inner layers (DRIL), intraretinal fluid, subretinal fluid (SRF) and epimacular membrane rip. Univariate analysis showed statistically significant association between all the aforementioned parameters with worse vision, except for cotton ball sign and SRF. Multivariate analysis found that MRT and severe DRIL were strongly correlated with worse vision ( p < 0.001). Conclusion: MRT and severe DRIL should be considered as negative prognostic factors for visual acuity.

scholarly journals Effect of internal limiting membrane peeling on postoperative visual acuity in macula-off rhegmatogenous retinal detachment

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255827
Author(s):  
Shumpei Obata ◽  
Masashi Kakinoki ◽  
Osamu Sawada ◽  
Yoshitsugu Saishin ◽  
Yusuke Ichiyama ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Cataract Surgery ◽  
Epiretinal Membrane ◽  
Rhegmatogenous Retinal Detachment ◽  
Internal Limiting Membrane ◽  
Ilm Peeling ◽  
Membrane Formation ◽  
Explanatory Variables ◽  
Long Duration

Purpose To investigate the effects of internal limiting membrane (ILM) peeling on visual acuity (VA) after rhegmatogenous retinal detachment (RRD) surgery. Methods This retrospective analysis examined the medical records of patients with RRD who underwent vitrectomy at 26 institutions. To detect prognostic factors of VA at 6 months postoperatively (post-VA), multivariate linear regression was performed with post-VA as the objective variable; ILM peeling, sex, age, preoperative VA (pre-VA), intraocular pressure, axial length, duration of RRD, and cataract surgery served as explanatory variables. Recurrence of RRD and epiretinal membrane formation within 6 months postoperatively were compared between groups of patients with and without ILM peeling, among patients with macula-on and macula-off RRD. Results The inclusion criteria were met by 523 eyes with a macula-on RRD and 364 eyes with a macula-off RRD. ILM peeling was performed in 85 eyes with a macula-on RRD and 57 eyes with a macula-off RRD. In eyes with a macula-on RRD, ILM peeling did not affect post-VA (p = 0.72). Vitrectomy without cataract surgery and poor pre-VA were significantly associated with poor post-VA (p = 0.01 and p < 0.001, respectively). In eyes with a macula-off RRD, ILM peeling, long duration of RRD, and poor pre-VA were significantly associated with poor post-VA (p = 0.037, p = 0.007, and p < 0.001, respectively). Recurrence of RRD and epiretinal membrane formation were similar between groups of patients with and without ILM peeling, among patients with macula-on and macula-off RRD. Retina sensitivity was not evaluated by microperimetry. Conclusion ILM peeling did not affect post-VA in eyes with a macula-on RRD, whereas post-VA was worse in eyes with ILM peeling than in eyes without peeling, among eyes with a macula-off RRD.

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