Role of multiparametric cardiac MR in patients with Antisynthetase syndrome

2021 ◽  
Author(s):  
Gemma Burcet
Keyword(s):  
Antisynthetase Syndrome ◽  
Cardiac Mr

The Role of Cardiac MR in New-Onset Heart Failure

2011 ◽  
Vol 13 (3) ◽  
pp. 185-193 ◽  
Author(s):  
Yong-Jin Kim ◽  
Raymond J. Kim
Keyword(s):  
Heart Failure ◽  
Cardiac Mr ◽  
New Onset

scholarly journals Role of Cardiac MR Imaging in Cardiomyopathies

2015 ◽  
Vol 56 (Supplement_4) ◽  
pp. 39S-45S ◽  
Author(s):  
C. M. Kramer
Keyword(s):  
Mr Imaging ◽  
Cardiac Mr

scholarly journals Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sara Remuzgo-Martínez ◽  
Belén Atienza-Mateo ◽  
J. Gonzalo Ocejo-Vinyals ◽  
Fernanda Genre ◽  
Verónica Pulito-Cueto ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Interstitial Lung Diseases ◽  
Allele Frequencies ◽  
Healthy Controls ◽  
Antisynthetase Syndrome ◽  
Connective Tissue Disorders ◽  
Mucin 1 ◽  
Potential Biomarker ◽  
Genetic Biomarker

AbstractMucin 1/Krebs von den Lungen-6 (KL-6) is proposed as a serum biomarker of several interstitial lung diseases (ILDs), including connective tissue disorders associated with ILD. However, it has not been studied in a large cohort of Caucasian antisynthetase syndrome (ASSD) patients. Consequently, we assessed the role of MUC1 rs4072037 and serum KL-6 levels as a potential biomarker of ASSD susceptibility and for the differential diagnosis between patients with ILD associated with ASSD (ASSD-ILD +) and idiopathic pulmonary fibrosis (IPF). 168 ASSD patients (149 ASSD-ILD +), 174 IPF patients and 523 healthy controls were genotyped for MUC1 rs4072037 T > C. Serum KL-6 levels were determined in a subgroup of individuals. A significant increase of MUC1 rs4072037 CC genotype and C allele frequencies was observed in ASSD patients compared to healthy controls. Likewise, MUC1 rs4072037 TC and CC genotypes and C allele frequencies were significantly different between ASSD-ILD+ and IPF patients. Additionally, serum KL-6 levels were significantly higher in ASSD patients compared to healthy controls. Nevertheless, no differences in serum KL-6 levels were found between ASSD-ILD+ and IPF patients. Our results suggest that the presence of MUC1 rs4072037 C allele increases the risk of ASSD and it could be a useful genetic biomarker for the differential diagnosis between ASSD-ILD+ and IPF patients.

Cardiac MR Imaging: New Advances and Role of 3T

2007 ◽  
Vol 15 (3) ◽  
pp. 291-300 ◽  
Author(s):  
Kambiz Nael ◽  
Michael Fenchel ◽  
Roya Saleh ◽  
J. Paul Finn
Keyword(s):  
Mr Imaging ◽  
Cardiac Mr

The Role of Cardiac MR Imaging in the Assessment of Patients with Cardiac Amyloidosis

2019 ◽  
Vol 27 (3) ◽  
pp. 453-463 ◽  
Author(s):  
Filipe Penna de Carvalho ◽  
Fernanda Erthal ◽  
Clerio F. Azevedo
Keyword(s):  
Mr Imaging ◽  
Cardiac Amyloidosis ◽  
Cardiac Mr

scholarly journals Myocarditis: imaging up to date

2020 ◽  
Vol 125 (11) ◽  
pp. 1124-1134
Author(s):  
Carlo Liguori ◽  
Davide Farina ◽  
Filippo Vaccher ◽  
Giovanni Ferrandino ◽  
Davide Bellini ◽  
...  
Keyword(s):  
Relaxation Time ◽  
Clinical Practice ◽  
Mr Imaging ◽  
Gold Standard ◽  
Acute Myocarditis ◽  
Myocardial Edema ◽  
T2 Relaxation Time ◽  
T2 Relaxation ◽  
Cardiac Mr

Abstract Myocarditis is an inflammatory disease of the heart muscle, diagnosed by histological, immunological, and immunohistochemical criteria. Endomyocardial biopsy represents the diagnostic gold standard for its diagnosis but is infrequently used. Due to its noninvasive ability to detect the presence of myocardial edema, hyperemia and necrosis/fibrosis, Cardiac MR imaging is routinely used in the clinical practice for the diagnosis of acute myocarditis. Recently pixel-wise mapping of T1 and T2 relaxation time have been introduced into the clinical Cardiac MR protocol increasing its accuracy. Our paper will review the role of MR imaging in the diagnosis of acute myocarditis.

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor
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