scholarly journals The Rehberg–Tareev test in assessing the glomerular filtration rate

2021 ◽  
Vol 93 (10) ◽  
pp. 1246-1248
Author(s):  
Irina N. Bobkova ◽  
Elena S. Kamyshova ◽  
Natalia V. Chebotareva

The history of glomerular filtration rate assessment is presented, an important step of which was the glomerular filtration rate evaluation by the endogenous creatinine clearance (known as the RehbergTareev test). The article highlights the diagnostic value of the RehbergTareev test and its place among modern methods for assessing glomerular filtration rate.

1996 ◽  
Vol 37 (3P2) ◽  
pp. 582-586
Author(s):  
S. Lundqvist ◽  
G. Edbom ◽  
S. Groth ◽  
U. Stendahl ◽  
S.-O. Hietala

Purpose: To determine a valid and practical routine for glomerular filtration rate measurement in gynaecologic cancer patients. Material and Methods: The established method, endogenous creatinine clearance, was compared to 51Cr-EDTA clearance and contrast medium clearance in 68 women with various gynaecologic carcinomas. Contrast medium clearance was determined in association with conventional urography (iohexol 300 mg I/ml, 40 ml) for evaluation of urinary tract involvement by the tumour. Automated X-ray fluorescence analysis equipment was used for the plasma analysis of iohexol and clearance calculations. Endogenous creatinine clearance and 51Cr-EDTA clearance were determined according to standard routine procedures. Simultaneous determinations of contrast medium clearance and 51Cr-EDTA clearance (n=33), contrast medium clearance and endogenous creatinine clearance (n=50), as well as 51Cr-EDTA clearance and endogenous creatinine clearance (n=30) were compared. Results and Conclusion: The mean differences were −2.8 (SD 6.6), −1.8 (SD 22.3), and 2.7 (SD 18.3) ml/min/1.73 m2, respectively. It is concluded that contrast medium clearance is as adequate as 51Cr-EDTA clearance for glomerular filtration rate measurement. We suggest that contrast medium clearance should replace endogenous creatinine clearance, especially in patients referred for urography.


1967 ◽  
Vol 06 (03) ◽  
pp. 204-310
Author(s):  
B. Malamos ◽  
A. S. Dontas ◽  
D. A. Koutras ◽  
S. Marketos ◽  
J. Sfontouris ◽  
...  

SummaryOne hundred 125I-sodium iothalamate and endogenous creatinine clearances in 36 subjects were compared with standard inulin clearance measurements. There was a very close correlation of the urine/plasma ratios between any two of the three clearances studied, hence both labelled iothalamate and creatinine can be relied upon for the estimation of the glomerular filtration rate in clinical practice. The mean ratio of 125I-sodium iothalamate to inulin clearance was 1.01 and that of creatinine to inulin 1.03. It is concluded that the clearance of 125I-sodium iothalamate can be substituted for the clearance of inulin in clinical determinations of the glomerular filtration rate but that in centres without radioisotope facilities the endogenous creatinine clearance can be used instead.


The Lancet ◽  
1964 ◽  
Vol 284 (7365) ◽  
pp. 874-876 ◽  
Author(s):  
G.M. Berlyne ◽  
S. Nilwarangkur ◽  
H. Varley ◽  
M. Hoerni

Author(s):  
Gisele da Silva da Fonseca ◽  
Vandréa Carla de Souza ◽  
Sarah Assoni Bilibio ◽  
Vanessa Carobin ◽  
Lígia Facin ◽  
...  

Abstract Introduction: The guidelines recommend estimating the glomerular filtration rate using serum creatinine-based equations as a predictor of kidney disease, preferably adjusted for local population groups. Methods: Cross-sectional study that evaluated the performance of four equations used for estimating GFR compared to endogenous creatinine clearance (ClCr) in 1,281 participants. Modification of Diet equations in Renal Disease Study Group (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), CKD-EPI with adjustment for local population (CKD-EPI local) and Full Age Spectrum (FAS) in comparison with endogenous creatinine clearance (ClCr). We used the Quantile Regression to calculate the median bias, interquartile range (IQR), Bland-Altman agreement analysis and 30% margin of error (P30). Results: The mean age of participants was 52.5 ± 16.5 years with 466 women (38%), median ClCr[IQR] of 92.0 [58.0; 122.0] mL/min/1.73 m2, with 320 (25%) participants presenting ClCr < 60 mL/min/1.73 m2. The performance of the local CKD-EPI and FAS equations were superior to MDRD and CKD-EPI in relation to variability (0.92 [0.89; 0.94]) and P30 (90.5% [88.7; 92, 0]). In the group with ClCr < 60 mL/min/1.73 m2, the local CKD-EPI and FAS equations showed less variability than the CKD-EPI and MDRD (0.90 [0.86; 0.98] and 1.05 [0.97; 1.09] vs. 0.63 [0.61; 0.68] and 0.65 [0.62; 0.70], P < 0.01) and best P30 (85.5) % [81.0; 90.0], 88.0% [84.0; 92.0] vs. 52.0% (46.0; 58.0) and 53.0% [47.0; 58 .5], P < 0.01). Conclusion: Local CKD-EPI and FAS equations performed better than CKD-EPI and MDRD when compared to ClCr.


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