Primary closure versus delayed primary closure in reducing surgical site infection in dirty midline abdominal operative wounds- A randomized controlled trial

2019 ◽  
Vol 9 (2) ◽  
pp. 86-90
Author(s):  
Rakesh Pandey ◽  
◽  
G K Venkatachalam ◽  
B Kanchana ◽  
◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Surgical Site Infection ◽  
Primary Closure ◽  
Controlled Trial ◽  
Site Infection ◽  
Randomized Controlled ◽  
Delayed Primary Closure

Circular pOlyethylene drape in preVEntion of suRgical site infection (COVER Trial): Study protocol of a randomized controlled trial

2018 ◽  
Author(s):  
Ri Na Yoo ◽  
Hyung Jin Kim ◽  
Jae Im Lee ◽  
Won-Kyung Kang ◽  
Bong-Hyeon Kye ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Abdominal Surgery ◽  
Surgical Site Infection ◽  
Controlled Trial ◽  
Dropout Rate ◽  
Site Infection ◽  
Gi Tract ◽  
Randomized Controlled ◽  
Wound Protector ◽  
Open Abdominal Surgery

Abstract Background: Surgical site infection (SSI) after abdominal surgery is still a significant morbidity associated with an increased socioeconomic burden and poor quality of life. SSI prevalence rates as high as 40% in cases of fecal contamination have been reported; however, current methods to reduce SSI are limited to elective abdominal surgery. Further evaluation of preventive measures for reducing SSI is necessary. Methods/design: The COVER trial investigates whether the application of a dual-ring circular plastic wound protector reduces the rate of SSI in patients undergoing open abdominal surgery related to the gastrointestinal (GI) tract, regardless of the type of wound classified by the Center for Disease Control (CDC). The COVER trial is a multicenter, randomized controlled clinical trial with two parallel arms – one using a wound protector and the other using conventional surgical dressing gauze. The primary outcome will measure the rate of SSI in two groups. Statistical analysis of the primary end point will be based on the intention-to-treat population. The sample size is determined to achieve a study power of 80% at 95% 2-sided confidence limits. Considering a dropout rate of up to 5%, a total of 458 patients, 229 patients in each group, will be enrolled in this study. Discussion: The COVER trial will provide high-quality evidence for using a circular polyethylene drape in open abdominal surgery for the GI tract in all types of wound. The design of the trial will deliver high external validity and clinical significance. Trial registration: The trial protocol was registered at ClinicalTrials.gov (NCT 03170843) on May 31, 2017. https://clinicaltrials.gov/ct2/show/NCT03170843?term=NCT+03170843&rank=1 Keywords: Circular polyethylene drape, Abdominal surgery, Gastrointestinal tract, Surgical site infection, Randomized controlled trial

scholarly journals Triclosan-coated sutures reduce surgical site infection after open vein harvesting in coronary artery bypass grafting patients: a randomized controlled trial†

2013 ◽  
Vol 44 (5) ◽  
pp. 931-938 ◽  
Author(s):  
Linda Thimour-Bergström ◽  
Christine Roman-Emanuel ◽  
Henrik Scherstén ◽  
Örjan Friberg ◽  
Tomas Gudbjartsson ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Surgical Site Infection ◽  
Controlled Trial ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Site Infection ◽  
Randomized Controlled ◽  
Vein Harvesting

A randomized controlled trial on irrigation of open appendectomy wound with gentamicin- saline solution versus saline solution for prevention of surgical site infection

2020 ◽  
Vol 81 ◽  
pp. 140-146 ◽  
Author(s):  
Sameh Hany Emile ◽  
Ahmed Hossam Elfallal ◽  
Mohamed Anwar Abdel-Razik ◽  
Mohamed El-Said ◽  
Ayman Elshobaky
Keyword(s):  
Randomized Controlled Trial ◽  
Surgical Site Infection ◽  
Saline Solution ◽  
Controlled Trial ◽  
Open Appendectomy ◽  
Site Infection ◽  
Solution Versus ◽  
Randomized Controlled

Effect of Peri-Operative Hyperoxygenation on Surgical Site Infection in Patients Undergoing Emergency Abdominal Surgery: A Randomized Controlled Trial

2021 ◽  
Author(s):  
Prasad Yerra ◽  
Sarath Chandra Sistla ◽  
Balamourougan Krishnaraj ◽  
Gomathi Shankar ◽  
Sujatha Sistla ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Abdominal Surgery ◽  
Surgical Site Infection ◽  
Controlled Trial ◽  
Site Infection ◽  
Randomized Controlled ◽  
Emergency Abdominal Surgery

scholarly journals Comparing Surgical Site Infection and Scar Cosmesis Between Conventional Linear Skin Closure Versus Purse-string Skin Closure in Stoma Reversal - A Randomized Controlled Trial

Cureus ◽  
2018 ◽  
Author(s):  
Sathasivam Sureshkumar ◽  
Kunnathoor Jubel ◽  
Manwar S Ali ◽  
Chellappa Vijayakumar ◽  
Anandhi Amaranathan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Surgical Site Infection ◽  
Controlled Trial ◽  
Skin Closure ◽  
Site Infection ◽  
Purse String ◽  
Stoma Reversal ◽  
Randomized Controlled
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