Over the past few years, an increase in intraoperative and obstetric anaphylactic episodes has been related to rubber exposure. Individuals at high-risk for sensitization to latex include health care workers,1,2 rubber industry professionals,3 and children with spina bifida or congenital urogenital abnormalities who undergo frequent medical procedures.4,5 However, severe reactions have been observed in other subjects.6,7 Therefore, identifying patients at risk for anaphylaxis is essential before performing medical procedures involving rubber exposure.
Recently,8 similarities in the protein content between natural rubber and several fruits have been found. Those proteins are cross-reactive and may cause severe allergic reactions if the patient comes in contact with rubber products and eats fruit.