NIOSH alert: preventing allergic reactions to natural rubber latex in the workplace.

1997 ◽  
PEDIATRICS ◽  
1994 ◽  
Vol 94 (5) ◽  
pp. 736-737
Author(s):  
Rafael Llátser ◽  
Concepción Zambrano ◽  
Baltasar Guillaumet

Over the past few years, an increase in intraoperative and obstetric anaphylactic episodes has been related to rubber exposure. Individuals at high-risk for sensitization to latex include health care workers,1,2 rubber industry professionals,3 and children with spina bifida or congenital urogenital abnormalities who undergo frequent medical procedures.4,5 However, severe reactions have been observed in other subjects.6,7 Therefore, identifying patients at risk for anaphylaxis is essential before performing medical procedures involving rubber exposure. Recently,8 similarities in the protein content between natural rubber and several fruits have been found. Those proteins are cross-reactive and may cause severe allergic reactions if the patient comes in contact with rubber products and eats fruit.


2019 ◽  
Vol 268 ◽  
pp. 01011
Author(s):  
Lih Jiun Yu ◽  
Christopher Wong Yoke Chi ◽  
Vishantini Tangavaloo ◽  
Keuw Wei Lim ◽  
Mou’ad A Tarawneh

The finished product natural rubber latex gloves consist of latex proteins, which may pose a risk of allergic reactions in some latex-sensitive individuals. The allergic reactions depend on mild exposure to heavy exposure. An alternative solution to allergic users, usage of latex-free gloves are lack of elasticity and less comfort. This study aims to investigate natural rubber films protein reduction via three types of leaching solvent: acetic acid, sodium hydroxide, and ethanol in the leaching process. Then the influence of leaching solvent concentration on the physical properties of natural rubber gloves was analyzed. It was found that the acetic acid performed greater protein reduction effect (30.07%), followed by sodium hydroxide (27.77%), whereas the ethanol was shown to be less significant to protein reduction. All samples were fulfilling the mechanical properties as required in ASTM standard.


Pharmacology ◽  
2020 ◽  
Vol 105 (11-12) ◽  
pp. 719-722 ◽  
Author(s):  
Mattia Giovannini ◽  
Francesca Mori ◽  
Simona Barni ◽  
Giulia Liccioli ◽  
Lucrezia Sarti ◽  
...  

Adverse reactions to natural rubber latex (NRL) represent a group of clinical manifestations that include non-allergic reactions and immediate-type or delayed-type allergic reactions. NRL sublingual immunotherapy (SLIT) has been demonstrated to be an effective and safe practice for latex clinical manifestations with good patient tolerance. A pediatric case of NRL allergy managed with an effective tailored SLIT is described. This case is compelling because the girl, who did not have an atopic background, suffered from NRL allergy with high reactivity and unique monosensitization. To the best of our knowledge, this is the first case with this characteristic described to date. Moreover, the SLIT follow-up time reported was unusually long, extending from childhood to adulthood. The case described highlights several problems of real-life management, and it demonstrates how the pediatric allergist plays a key role in the management of all these issues in order to succeed in guiding the patient through the immunotherapy process with a personalized approach, in line with the precision medicine principles. However, further long-term clinical studies are needed to better define the natural history of NRL allergy and find new potential biomarkers of response to NRL immunotherapy.


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