The Effect of Depression Comorbidity on the Quality of Life of Patients with Type 2 Diabetes Mellitus: Meta-Analysis

Author(s):  
Rofana Aghniya ◽  
◽  
Bhisma Murti ◽  
Didik Gunawan Tamtomo ◽  
Hanung Prasetya ◽  
...  

Background: The prevalence of depression is two to three times higher in diabetic patients, while most cases remain undiagnosed. The quality of life is substantially and adversely affected by depression. This study aimed to estimate the effect of depression comorbidity on patients’ quality of life with type 2 diabetes mellitus. Subjects and Method: This was a meta-analysis and systematic review. The study was conducted by collecting published articles from PubMed, ProQuest, Science Direct, Scopus, Spinger Link, Clinical Key, and Google Scholar databases. Keywords used “comorbidity depression and DM”, “depression and quality of life and DM and cross sectional study”, “depression and quality of life and DM and adjusted odd ratio”, “depression or diabetes”, “depression or quality of life or DM or adjusted odd ratio”. The study criteria were full text, using cross-sectional study design, and reporting adjusted Odds Ratio (aOR). The selected articles were analyzed using Revman 5.3 with fixed effect models. Results: 8 studies from Uganda, Iran, United States, United Kingdom, Australia, Nigeria, Brazil, and Nepal, were selected for this study. Current study reported that type 2 DM patients with depression had lower quality of life than those without depression (aOR= 2.72; 95% CI= 0.73 to 10.07; p<0.0001) Conclusion: Type 2 DM patient with depression has lower quality of life than those without depression. Keywords: depression, quality of life, diabetes mellitus Correspondence: Rofana Aghniya. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: +685523528340.

2021 ◽  
Author(s):  
Wu Chao ◽  
Ge Yiling ◽  
Zhang Xinyan ◽  
Liu Mingchao ◽  
Heng Chunni ◽  
...  

Abstract Purpose This study aims to explore the incidence of hypoglycemia in patients with type 2 diabetes mellitus (T2DM) and the influence of hypoglycemia on the specific quality of life in T2DM patients.Methods It was a comparative cross-sectional study consisting of 519 T2DM patients in Xi'an, China and patients were investigated by self-reported hypoglycemia and specific quality of life questionnaires during September 2019 to January 2020. Descriptive analysis, t-test, Chi-square test, hierarchical regression analysis and stepwise multiple regression analysis were used to assess the influence of hypoglycemia on the specific quality of life. Results The incidence of hypoglycemia in T2DM patients was 32.18%. The mean score of specific quality of life in diabetes without hypoglycemia was 57.33±15.36 and was 61.56±17.50 in those with hypoglycemia, which indicated that hypoglycemia had a serious impact on the quality of life diabetics (t=-5.172, p=0.000). In the Univariate analysis of specific quality of life, age, education background, marital status, living status, duration of diabetes, monthly income per capita were independent and significant factors associated with specific quality of life of two groups of T2DM patients (P<0.05). In the hierarchical regression analysis, the duration of the diabetes more than 11 years and the frequency of hypoglycemia more than 6 times in half a year entered the equation of specific quality of life of 519 diabetics respectively (P<0.001). In multiple linear regression analysis, age, marital status and income both entered the regression equation of quality of life of the two groups (P<0.05).Conclusion Hypoglycemia will have a serious impact on the quality of life of T2DM patients. In order to improve the living quality in diabetics, effective measurements should be taken to strengthen the management of blood glucose and avoid hypoglycemia.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Chao Wu ◽  
Yi-Ling Ge ◽  
Xin-Yan Zhang ◽  
Ming-Chao Liu ◽  
Chun-Ni Heng ◽  
...  

Abstract Purpose This study aims to explore the incidence of hypoglycemia in patients with type 2 diabetes mellitus (T2DM) and the influence of hypoglycemia on the specific quality of life in T2DM patients. Methods It was a comparative cross-sectional study consisting of 519 T2DM patients in Xi'an, China and patients were investigated by self-reported hypoglycemia and specific quality of life questionnaires from September 2019 to January 2020. Descriptive analysis, t-test, Chi-square test, hierarchical regression analysis and stepwise multiple regression analysis were applied to assess the influence of hypoglycemia on the specific quality of life. Results The incidence of hypoglycemia in T2DM patients was 32.18%. The mean score of specific quality of life in diabetes without hypoglycemia was 57.33 ± 15.36 and was 61.56 ± 17.50 in those with hypoglycemia, which indicated that hypoglycemia had a serious impact on the quality of life of diabetics (t = − 5.172, p = 0.000). In the Univariate analysis of specific quality of life, age, education background, marital status, living status, duration of diabetes, monthly income per capita were independent and significant factors associated with specific quality of life of two groups of T2DM patients (p < 0.05). In the hierarchical regression analysis, the duration of the diabetes more than 11 years and the frequency of hypoglycemia more than 6 times in half a year entered the equation of specific quality of life of 519 diabetics respectively (p < 0.001). In multiple linear regression analysis, age, marital status and income all entered the regression equation of quality of life of the two groups (p < 0.05). Conclusion Hypoglycemia will have a serious impact on the quality of life of T2DM patients. In order to improve the living quality in diabetics, effective measurements should be taken to strengthen the management of blood glucose and to avoid hypoglycemia.


2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Jessie N. Zurita-Cruz ◽  
Leticia Manuel-Apolinar ◽  
María Luisa Arellano-Flores ◽  
Alejandro Gutierrez-Gonzalez ◽  
Alma Gloria Najera-Ahumada ◽  
...  

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