Effect on Neuropsychiatric Disorders of Organophosphate Pesticides Exposure among Rice Farmers in Sukoharjo, Central Java

ABSTRACT Background: Chronic exposure to organophosphate pesticides can increase the risk of neuropsychiatric disorders, including depression and anxiety. Unsafe behavior from farmers will endanger the health of farmers, especially in the form of neuropsychiatric disorders (depression and anxiety). This study aimed to analyze the effects of pesticide exposure and psychosocial determinants on depression and anxiety. Subjects and Method: A retrospective cohort study was conducted in Sukoharjo, Central Java. The study population was rice farmers. A sample of 200 rice farmers who use organophospate pesticide was selected by fixed exposure sampling. The dependent variable was neuropsychiatry (anxiety and depression). The independent variables were exposure to organophospate pesticide, had family history of depression, loss and grief, post trauma, work stress, and the use of personal protective equipment (PPE). The data were collected by questionnaire and analyzed by a multiple linear regression. Results: The risk of depression increased with high exposure to organophospate pesticide (b= 0.15; 95% CI= 0.05 to 0.26; p= 0.005), had family history of depression (b= 5.10; 95% CI= 2.60 to 7.60; p<0.001), loss and grief (b= 2.94; 95% CI= 0.76 to 5.11; p= 0.008), post trauma (b= 2.57; 95% CI= 0.24 to 4.89; p= 0.031), and work stress (b= 0.16; 95% CI= 0.05 to 0.27; p= 0.005). The risk of depression decreased with the use of PPE (b= -0.69; 95% CI= -1.32 to -0.076; p= 0.028). The risk of anxiety increased with high exposure to organophospate pesticide (b= 0.13; 95% CI= 0.02 to 0.24; p= 0.025), post trauma (b= 5.96; 95% CI= 3.48 to 8.44; p<0.001), loss and grief (b= 3.39; 95% CI= 1.07 to 5.71; p<0.001), had family history of depression (b= 2.95; 95% CI= 0.29 to 5.62; p= 0.004), and work stress (b= 0.19; 95% CI= 0.07 to 0.30; p=0.002). The risk of anxiety decreased with the use of PPE (b= -0.09; 95% CI= -1.57 to -0.024; p=0.008). Conclusion: The risk of depression increases with high exposure to organophospate pesticide, family history of depression, loss and grief, post trauma, and work stress. The risk of depression decreases with the use of PPE. The risk of anxiety increases with high exposure to organophospate pesticide, post trauma, loss and grief, had family history of depression, and work stress. The risk of anxiety decreases with the use of PPE. Keywords: Neuropsychiatry disorder, depression, anxiety Correspondence: Ayu Laela Fitriyani. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: +625796333986. DOI: https://doi.org/10.26911/the7thicph.01.48

Effectiveness of Dry Extract Mahoni Seed Consumption on Blood Sugar Level in Diabetes Mellitus

ABSTRACT Background: An increase in blood sugar levels caused diabetes mellitus, and various other health complications. One of the herbal therapy approaches can be used by consuming mahogany seeds which are believed to reduce blood glucose levels. The purpose of this study was to determine the effectiveness of consuming mahogany seeds to reduce blood sugar levels. Subjects and Method: This was a quasi-experiment with non-randomized control group pretest-posttest design conducted on March 24-26 2020. A sample of 22 respondents was divided into 2 groups: treatment group and control group selected by purposive sampling. The data was collected by observation. The data was analysed by Paired t-test. Results: The treatment group before consuming the dry extract of Mahogany seeds (Mean= 258.27; SD= 46.98), and after consuming the dry extract of Mahogany seeds (Mean= 185.36; SD= 38.85). In the control group, before consuming the extract of Mahogany seed ekring (Mean= 224.27; SD= 14.73), and after consuming Mahogany seed extract (Mean= 213.27; SD= 6.75). It was statistically significant (p= 0.001). Conclusion: Consumption of dry extract of Mahogany seeds effectively reduces blood sugar levels in patients with Diabetes Mellitus. Consumption of mahogany seeds can be used as a complementary therapy in nursing to reduce blood sugar. Keywords: Consumption of dry extract of Mahogany Seeds, Diabetes Mellitus. Correspondence: Ganda Ardiansyah. School of health science Satria Bhakti Nganjuk, East Java. Email: gandaa- [email protected] DOI: https://doi.org/10.26911/the7thicph.05.25

Acupuncture Therapy in Reducing Pain in Patients with Low Back Pain: Meta Analysis

ABSTRACT Background: With growing evidence of high prevalence in developing countries, LBP is no longer recognized as a disorder confined to high-income nations but is a major health problem globally. The functional limitations and consequent disability create a heavy economic burden on individuals and society. This study aimed to acupuncture therapy in reducing pain in patients with low back pain. Subjects and Method: A meta-analysis and systematic review was conducted by search published articles from PubMed, Google Schoolar, Mendeley, Hindawi, and Clinical key databases. Keywords used “acupuncture low back pain” OR “acupuncture chronic pain” AND “efficacy acupuncture” AND “chronic low back pain” AND “effect acupuncture for low back pain” AND “randomized controlled trial” AND “visual analogue scale”. The inclusion criteria were full text and using randomized controlled trial (RCT) study design. The articles were selected by PRISMA flow chart and the quantitative data were analyzed by Revman 5.3. Results: 7 studies were met criteria. This study showed that acupuncture therapy reduced pain in patients with low back pain (Mean Difference= -0.40; 95% CI= -0.80 to 0.01; p= 0.05) with heterogeneity I2= 83%. Conclusion: Acupuncture therapy reduces pain in patients with low back pain. Keywords: low back pain, acupuncture chronic low back pain, randomized controlled trial. Correspondence: Elisa Novitasari. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 085727851938. DOI: https://doi.org/10.26911/the7thicph.05.43

The Correlation between Secretory Phospholipase A2 Type IIA Levels and Mean Platelet Volume among Type 2 Diabetes Mellitus Patients

Background: Platelet activity plays a role in the occurrence of diabetic angiopathy with an increase in mean platelet volume (MPV) as a marker of platelet activity. Platelet activity is influenced by phospholipase A2 type IIA (sPLA2 type IIA), which is a lipid-mediating enzyme that connects the pathogenesis of Diabetes Mellitus (DM) with complications of diabetic angiopathy. This study aimed to examine the relationship between levels of type IIA sPLA2 and MPV among type II DM patients. Subjects and Method: This was a cross-sectional study. A total of 63 patients with type II DM was selected for this study. The inclusion criteria for the study subjects were type 2 diabetes mellitus patients who did not experience an infectious disease, acute inflammation, trauma, surgery or malignancy, anemia, taking antiplatelet drugs, having abnormal platelet counts, and smoking. The dependent variable was levels of type IIA sPLA2. The independent variable was MPV. The data were obtained from the medical records of Prof. Dr. Soerojo Mental Hospital, Magelang. The data were analyzed using Spearman correlation test. Results: The study showed the median level of sPLA2 type IIA was 3841.50 ng / dL and the average MPV value was 7.36 fl. The results of the Spearman correlation analysis showed that there was no relationship between sPLA2 type IIA and MPV (p = 0.551), but there was a tendency for an increase in type IIA sPLA2 followed by an increase in MPV value (r = 0.077). There was a difference in the average MPV value in the subject group with DM ≤ 10 years and> 10 years (p = 0.009), and it was statistically significant. Conclusion: There is a tendency for an increase in type IIA sPLA2 followed by an increase in the MPV value among type II DM patients. Keywords: type II diabetes melitus, type IIA sPLA2 enzyme, mean platelet volume Correspondence: Woro Ayu Sekararum. Faculty of Medicine, Universitas Pembangunan Nasional ‘Veteran’ Jakarta. Jl, Rumah Sakit Fatmawati, Pondok Labu, South Jakarta, Indonesia. E-mail: [email protected]. Mobile: 0811975511 DOI: https://doi.org/10.26911/the7thicph.01.09

Association between Receptive Language Skill and Social Communication Skill among Preschool Children: Evidence from Surakarta, Central Java

ABSTRACT Background: Receptive language skills are crucial for the development of cognitive and social/emotional skills. Children with social communication problems are at risk of failure in the academic field, difficulty forming friendships, and social exclusion. This study aimed to examine the association between receptive language skill and social communication skill among preschool children. Subjects and Method: This was a cross sectional study conducted in Surakarta, Central Java, in January 2020. A sample of 200 pre-school children was selected by simple random sampling. The dependent variable was social communication. The independent variables were receptive language skill, parenting style, gender, and birth order. The data were collected by questionnaire and analyzed by a multiple linear regression. Results: Good social communication increased with good receptive language skill (OR= 3.21; 95% CI= 0.01 to 0.04; p= 0.002), first birth order (OR= 3.71; 95% CI= 0.79 to 1.47; p<0.001), democratic parenting style (OR= 5.21; 95% CI= 0.09 to 0.20; p<0.001), and female gender (OR= 5.23; 95% CI= 0.89 to 1.97; p<0.001). Conclusion: Good social communication increases with good receptive language skill, first birth order, democratic parenting style, and female gender. Keywords: social communication, receptive language skill Correspondence: Nadya Susanti. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: 081568222014 DOI: https://doi.org/10.26911/the7thicph.03.101

The Difference of Development in Children Aged 6 Months Received Exclusive Breastfeeding Versus Formula Milk in Ciptomulyo Health Center, Malang, East Java

ABSTRACT Background: Development during infancy occurs rapidly. Parent ability to meet their nutritional needs is needed to obtain optimal infants development. This study was to investigate the difference of development in children aged 6 months received exclusive breastfeeding versus formula milk Subjects and Method: A cross-sectional study was conducted at Ciptomulyo health center, Malang, East Java, from April to May 2017. A sample of 17 infants who received exclusive breastfeeding and 19 infants who received formula milk was selected by total sampling. The dependent variable was child development. The independent variables were exclusive breastfeeding and formula milk. Child development was measured by Denver Development Screening Test. Mean difference of child development between groups was measured by Mann Whitney. Results: Development score in children aged 6 months who received exclusive breastfeeding (Mean= 0.53; SD= 0.24) was higher than children who received formula milk (Mean= 0.47; SD= 0.01), and it was statistically significant (p= 0.003). Conclusion: Development score in children aged 6 months who received exclusive breastfeeding is higher than children who received formula milk. Keywords: child development, exclusive breastfeeding, formula milk Correspondence: Milatur Rosyidah. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 089620575849. DOI: https://doi.org/10.26911/the7thicph.03.111

Nitrate in Groundwater and Health Risk Assessment: A Cross-Sectional Study in Three Villages in Tanah Merah District, Kelantan, Malaysia During Paddy Pre-Planting Season

ABSTRACT Introduction: Contamination of nitrate is one of the most common groundwater problems worldwide. Around 70% of residents in the state of Kelantan still rely on groundwater as their primary source of water supply. Extensive usage of fertilizer in agricultural areas may cause nitrate leaching into the groundwater. This study aimed to determine the level of nitrate in groundwater and health risk assessment at three villages in Tanah Merah District, Kelantan, Malaysia. Subjects and Method: This was a cross-sectional study conducted at Tanah Merah district, Kelantan, in January 2020. A total of 52 residents was selected by purposive sampling. The inclusion criteria for study subjects were long life residents, age ≥18 years old, and groundwater as a primary source of drinking supply. The study variables were (1) Level of nitrate in groundwater measured according to age (year), depth (meter), and distance (meter) of well from the agricultural area; and (2) Health risk assessment measured by hazard quotient (HQ). A set of questionnaires consisted of four sections to gather information related to socio-demographic, water usage, living environment, and health status. Groundwater samples were collected in duplicates and were analysed using a Hanna Instruments portable pH/ORP/ISE meter with an attached nitrate electrode. The data were reported descriptively. Results: Nitrate levels were found to be under the maximum acceptable value of 10 mg/L, as stated by the Drinking Water Quality Standard of Malaysia. Nitrate level ranged from 0.22 to 8.81 mg/L (Mean= 2.94; SD= 2.27). Spearman rho correlation showed that nitrate level was significantly and negatively correlated the age of wells (r= -0.31; p= 0.025). Nitrate level was not significantly correlated with the depth (r= 0.19; p= 0.183) and distance of wells (r= -0.05; p= 0.751). Hazard quotient (HQ) for all study subjects was <1, which means that exposure to nitrate contained drinking water in study subjects was not detrimental to health. Conclusion: Nitrate levels were below the maximum acceptable value, but continuous monitoring from health authorities is essential since other seasons of paddy planting may contribute higher deposition of nitrate into groundwater. Keywords: nitrate, groundwater, levels, hazard quotient, Tanah Merah Correspondence: Muhammad Syafiq N. Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia. UPM Serdang, Selangor, Malaysia. Email: [email protected]. Mobile: +601140731881. DOI: https://doi.org/10.26911/the7thicph.01.27

Determinants of Health Visit among Mothers with Toddlers at the Integrated Health Post, Nganjuk District, East Java

ABSTRACT Background: Regular visit to the integrated health post is essential to monitor health and nutritional status of children under five years of age. However, the frequency of visits remained low in Nganjuk District, East Java. This study aimed to determine the factors affecting health visit of children under five at the integrated health post in Nganjuk District, East Java. Subjects and Method: This was a cross-sectional study conducted at Ngetos Integrated Health Post, Nganjuk, East Java, in April 2019. A sample of 100 children under five was selected for this study. The dependent variable was visit to the integrated health post. The independent variables were child age, maternal education, maternal work status, and motivation. The data were collected using questionnaires. The data were analyzed by multiple logistic regression. Results: Visit of children under five years of age to the integrated health post increased with child age (OR= 1.60; 95% CI= 0.90 to 12.20; p= 0.071), higher maternal education (OR= 4.66; 95% CI= 2.13 to 28.14; p= 0.002), working mothers (OR= 2.90; 95% CI= 1.57 to 26.45; p= 0.010), and higher motivation (OR= 2.45; 95% CI= 1.35 to 19.05; p= 0.016). Conclusion: Visit of children under five years of age to the integrated health post increases with child age, higher maternal education, working mothers, and higher motivation. Keywords: children under five years of age, mothers, integrated health post Correspondence: Ike Nurrochmawati. School of Health Sciences Satria Bhakti, Nganjuk. Jl. Panglima Sudirman VI Nganjuk, East Java. Email: [email protected]. Mobile: +6282141578108. DOI: https://doi.org/10.26911/the7thicph.03.71

Use of Gadget on Child Development in Children Aged 3-5 Years: Evidence from Melawi, West Kalimantan

ABSTRACT Background: Children nowadays use gadgets intensively, which can lead to addiction. The frequency or intensity of the children in using gadgets may affect their development. This study aimed to examine the use of gadgets on child development in children aged 3-5 years. Subjects and Method: A cross sectional study was conducted in Melawi, East Kalimantan, Indonesia, from August to September 2019. A sample of 200 children 3-5 years old was selected by fixed exposure sampling. The dependent variable was child development. The independent variables were gadget use, maternal age, maternal education, maternal employment, family income, number of children, and type of family. The data were collected by questionnaire and analyzed by a multiple linear regression. Results: Children development aged 3-5 years increased with maternal age ≥20 years old (b= 0.73; 95% CI= 0.11 to 1.35; p= 0.020), maternal education ≥Senior high school (b= 0.71; 95% CI= 0.34 to 1.08; p<0.001), family income ≥Rp 2,288,000 (b= 0.85; 95% CI= 0.42 to 1.28; p<0.001), and nuclear family type (b= 0.57; 95% CI= 0.25 to 0.89; p= 0.001). Children development aged 3-5 years decreased with gadget use (b= -0.69; 95% CI= -0.98 to -0.40; p<0.001), employed mother (b= -0.75; 95% CI= -1.05 to -0.45; p <0.001), and number of children >2 (b= -1.13; 95% CI= -1.46 to -0.80; p<0.001). Conclusion: Perkembangan anak usia 3-5 tahun meningkat dipengaruhi oleh usia ibu, pendidikan ibu, pendapatan keluarga, dan tipe keluarga inti. Perkembangan anak usia 3-5 tahun menurun pada anak yang menggunakan gadget, pekerjaan ibu, dan jumlah anak. Keywords: gadget use, children aged 3-5 years Correspondence: Livia Calorina. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta, Central Java, Indonesia. Email: [email protected]. Mobile: 081346595497 DOI: https://doi.org/10.26911/the7thicph.03.87

Factors Affecting Stunting among Children Under Five Years of Age in Banyuwangi, East Java

ABSTRACT Background: Stunting, chronic malnutrition, results from the exposure of the fetus and young child to nutritional deficiency and infectious disease. In Indonesia, 30.8% of children were stunted, in which 26.2% was in East Java and 8.1% Banyuwangi Regency. This study aimed to investigate the factors affecting stunting among children under five years of age in Banyuwangi, East Java. Subjects and Method: This was a cross-sectional study conducted at Klatak and Wonosobo Community Health Centers, Central Java. a sample of 60 children under five years of age was selected for this study. The study variables were child’s gender, maternal age at pregnancy, maternal education, maternal work status, iron intake, history of chronic energy deficiency, exclusive breastfeeding, supplementary feeding, and history of infectious disease. The frequency distribution data were reported descriptively. Results: The majority of stunted children under study were male (53.3%). Most of the women were at age 20 to 34 years during pregnancy (58.3%). As many as 73.3% mothers were low educated. Most of the mothers were housewives (85%). 78.3% of women took iron supplement during pregnancy. Most of the children did not have the history of chronic energy deficiency (60%). Most of the children received exclusive breastfeeding (61.7%) and supplementary feeding (65%). Only a few children had the history of infectious disease (6.7%). Conclusion: The characteristics of subjects under study vary with maternal age at pregnancy, maternal education, maternal work status, iron intake, history of chronic energy deficiency, exclusive breastfeeding, supplementary feeding, and history of infectious disease. Keywords: stunting, children under five years of age, factors Correspondence: Endah Kusuma Wardani. Midwifery Program, School of Health Sciences Banyuwangi. Jl. Letkol Istiqlah No. 109, Banyuwangi, East Java, 68422. Email: [email protected]. Mobile: +6282257193736. DOI: https://doi.org/10.26911/the7thicph.03.80