scholarly journals PET microdose study

2011 ◽  
Vol 26 (4) ◽  
pp. 410-417
Author(s):  
Michio Senda ◽  
Hiromitsu Kageyama
Keyword(s):  
Microdose Study

scholarly journals O-203b Paediatric Microdose Study Of [14c]paracetamol To Study Drug Metabolism Using Accelerated Mass Spectrometry: Proof Of Concept

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A102.1-A102
Author(s):  
MG Mooij ◽  
E van Duijn ◽  
CA Knibbe ◽  
W Vaes ◽  
B Fabriek ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Drug Metabolism ◽  
Study Drug ◽  
Proof Of Concept ◽  
Microdose Study

An Assessment of the Oral Bioavailability of Three Ca-Channel Blockers Using a Cassette-Microdose Study: A New Strategy for Streamlining Oral Drug Development

2015 ◽  
Vol 104 (9) ◽  
pp. 3154-3161 ◽  
Author(s):  
Shinji Yamashita ◽  
Makoto Kataoka ◽  
Yuki Suzaki ◽  
Hiromitsu Imai ◽  
Takuya Morimoto ◽  
...  
Keyword(s):  
Drug Development ◽  
Oral Bioavailability ◽  
Oral Drug ◽  
Channel Blockers ◽  
Ca Channel ◽  
Ca Channel Blockers ◽  
New Strategy ◽  
Microdose Study

A microdose study of 14C-AR-709 in healthy men: pharmacokinetics, absolute bioavailability and concentrations in key compartments of the lung

2013 ◽  
Vol 69 (9) ◽  
pp. 1673-1682 ◽  
Author(s):  
G. Lappin ◽  
M. J. Boyce ◽  
T. Matzow ◽  
S. Lociuro ◽  
M. Seymour ◽  
...  
Keyword(s):  
Absolute Bioavailability ◽  
Healthy Men ◽  
Microdose Study

Microdose Study of 14C-Acetaminophen With Accelerator Mass Spectrometry to Examine Pharmacokinetics of Parent Drug and Metabolites in Healthy Subjects

2010 ◽  
Vol 88 (6) ◽  
pp. 824-830 ◽  
Author(s):  
Z Tozuka ◽  
H Kusuhara ◽  
K Nozawa ◽  
Y Hamabe ◽  
I Ikushima ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Accelerator Mass Spectrometry ◽  
Healthy Subjects ◽  
Parent Drug ◽  
Microdose Study

Clinical microdose study of gossypol: Effect on sperm motility and renal function

Contraception ◽  
1988 ◽  
Vol 37 (2) ◽  
pp. 153-162 ◽  
Author(s):  
J. Frick ◽  
W. Aulitzky ◽  
N.R. Kalla
Keyword(s):  
Renal Function ◽  
Sperm Motility ◽  
Microdose Study

Absolute oral bioavailability and pharmacokinetics of canagliflozin: A microdose study in healthy participants

2014 ◽  
Vol 4 (4) ◽  
pp. 295-304 ◽  
Author(s):  
Damayanthi Devineni ◽  
Joseph Murphy ◽  
Shean-Sheng Wang ◽  
Hans Stieltjes ◽  
Paul Rothenberg ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
Microdose Study ◽  
Absolute Oral Bioavailability ◽  
Healthy Participants

scholarly journals Utility of a microdose study for drug discovery and development

2013 ◽  
Vol 141 (3) ◽  
pp. 126-130 ◽  
Author(s):  
Yoshiyuki Yamaura
Keyword(s):  
Drug Discovery ◽  
Drug Discovery And Development ◽  
Microdose Study

Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS

2010 ◽  
Vol 35 (2) ◽  
pp. 169-175 ◽  
Author(s):  
A. Yamazaki ◽  
Y. Kumagai ◽  
N. Yamane ◽  
Z. Tozuka ◽  
Y. Sugiyama ◽  
...  
Keyword(s):  
P Glycoprotein ◽  
Microdose Study

scholarly journals A Combined Accelerator Mass Spectrometry-Positron Emission Tomography Human Microdose Study with 14C- and 11C-Labelled Verapamil

2011 ◽  
Vol 50 (2) ◽  
pp. 111-120 ◽  
Author(s):  
Claudia C. Wagner ◽  
Marie Simpson ◽  
Markus Zeitlinger ◽  
Martin Bauer ◽  
Rudolf Karch ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Positron Emission Tomography ◽  
Accelerator Mass Spectrometry ◽  
Emission Tomography ◽  
Positron Emission ◽  
Microdose Study
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