scholarly journals Use of an inactivated vaccine in mitigating pandemic influenza A(H1N1) spread: a modelling study to assess the impact of vaccination timing and prioritisation strategies

2009 ◽  
Vol 14 (41) ◽  
Author(s):  
V Sypsa ◽  
I Pavlopoulou ◽  
A Hatzakis
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Inactivated Vaccine ◽  
Binary File ◽  
Influenza A H1n1 ◽  
The Impact ◽  
Modelling Study

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Mortality of 2009 pandemic influenza A(H1N1) in Germany

2010 ◽  
Vol 15 (49) ◽  
Author(s):  
H Wilking ◽  
S Buda ◽  
E von der Lippe ◽  
D Altmann ◽  
G Krause ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Contemporary Seasonal Influenza A (H1N1) Virus Infection Primes for a More Robust Response To Split Inactivated Pandemic Influenza A (H1N1) Virus Vaccination in Ferrets

2010 ◽  
Vol 17 (12) ◽  
pp. 1998-2006 ◽  
Author(s):  
Ali H. Ellebedy ◽  
Thomas P. Fabrizio ◽  
Ghazi Kayali ◽  
Thomas H. Oguin ◽  
Scott A. Brown ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Seasonal Influenza ◽  
H1n1 Virus ◽  
H1n1 Influenza ◽  
Influenza Viruses ◽  
Inactivated Vaccine ◽  
H1n1 Influenza Virus ◽  
Influenza A H1n1

ABSTRACT Human influenza pandemics occur when influenza viruses to which the population has little or no immunity emerge and acquire the ability to achieve human-to-human transmission. In April 2009, cases of a novel H1N1 influenza virus in children in the southwestern United States were reported. It was retrospectively shown that these cases represented the spread of this virus from an ongoing outbreak in Mexico. The emergence of the pandemic led to a number of national vaccination programs. Surprisingly, early human clinical trial data have shown that a single dose of nonadjuvanted pandemic influenza A (H1N1) 2009 monovalent inactivated vaccine (pMIV) has led to a seroprotective response in a majority of individuals, despite earlier studies showing a lack of cross-reactivity between seasonal and pandemic H1N1 viruses. Here we show that previous exposure to a contemporary seasonal H1N1 influenza virus and to a lesser degree a seasonal influenza virus trivalent inactivated vaccine is able to prime for a higher antibody response after a subsequent dose of pMIV in ferrets. The more protective response was partially dependent on the presence of CD8+ cells. Two doses of pMIV were also able to induce a detectable antibody response that provided protection from subsequent challenge. These data show that previous infection with seasonal H1N1 influenza viruses likely explains the requirement for only a single dose of pMIV in adults and that vaccination campaigns with the current pandemic influenza vaccines should reduce viral burden and disease severity in humans.

The Impact of Pandemic Influenza A H1N1 2009 on Australian Lung Transplant Recipients

2011 ◽  
Vol 11 (3) ◽  
pp. 568-574 ◽  
Author(s):  
B. J. H. Ng ◽  
A. R. Glanville ◽  
G. Snell ◽  
M. Musk ◽  
M. Holmes ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Influenza A H1n1 ◽  
Lung Transplant Recipients ◽  
The Impact

The impact of primer and probe-template mismatches on the sensitivity of pandemic influenza A/H1N1/2009 virus detection by real-time RT-PCR

2010 ◽  
Vol 48 (2) ◽  
pp. 91-95 ◽  
Author(s):  
Chonticha Klungthong ◽  
Piyawan Chinnawirotpisan ◽  
Kittinun Hussem ◽  
Thipwipha Phonpakobsin ◽  
Wudtichai Manasatienkij ◽  
...  
Keyword(s):  
Real Time ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Virus Detection ◽  
Rt Pcr ◽  
Influenza A H1n1 ◽  
The Impact

scholarly journals Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

2012 ◽  
Vol 12 (9) ◽  
pp. 687-695 ◽  
Author(s):  
Fatimah S Dawood ◽  
A Danielle Iuliano ◽  
Carrie Reed ◽  
Martin I Meltzer ◽  
David K Shay ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
Influenza A H1n1 ◽  
Modelling Study

Transmission and control in an institutional pandemic influenza A(H1N1) 2009 outbreak

2011 ◽  
Vol 140 (6) ◽  
pp. 1102-1110 ◽  
Author(s):  
N. ARINAMINPATHY ◽  
N. RAPHAELY ◽  
L. SALDANA ◽  
C. HODGEKISS ◽  
J. DANDRIDGE ◽  
...  
Keyword(s):  
High Risk ◽  
Infection Control ◽  
Pandemic Influenza ◽  
Summer School ◽  
Influenza A ◽  
Control Measures ◽  
Infection Control Measures ◽  
Influenza A H1n1 ◽  
Hygiene Measures ◽  
The Impact

SUMMARYA pandemic influenza A(H1N1) 2009 outbreak in a summer school affected 117/276 (42%) students. Residential social contact was associated with risk of infection, and there was no evidence for transmission associated with the classroom setting. Although the summer school had new admissions each week, which provided susceptible students the outbreak was controlled using routine infection control measures (isolation of cases, basic hygiene measures and avoidance of particularly high-risk social events) and prompt treatment of cases. This was in the absence of chemoprophylaxis or vaccination and without altering the basic educational activities of the school. Modelling of the outbreak allowed estimation of the impact of interventions on transmission. These models and follow-up surveillance supported the effectiveness of routine infection control measures to stop the spread of influenza even in this high-risk setting for transmission.

scholarly journals Seroprevalence of 2009 pandemic influenza A(H1N1) virus in Australian blood donors, October – December 2009

2010 ◽  
Vol 15 (40) ◽  
Author(s):  
J McVernon ◽  
K Laurie ◽  
T Nolan ◽  
R Owen ◽  
D Irving ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Blood Donors ◽  
H1n1 Virus ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Transmissibility of 2009 pandemic influenza A(H1N1) in New Zealand: effective reproduction number and influence of age, ethnicity and importations

2010 ◽  
Vol 15 (24) ◽  
Author(s):  
S Paine ◽  
G N Mercer ◽  
P M Kelly ◽  
D Bandaranayake ◽  
M G Baker ◽  
...  
Keyword(s):  
New Zealand ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Reproduction Number ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Pandemic influenza A(H1N1)v in New Zealand: the experience from April to August 2009

2009 ◽  
Vol 14 (34) ◽  
Author(s):  
M G Baker ◽  
N Wilson ◽  
Q S Huang ◽  
S Paine ◽  
L Lopez ◽  
...  
Keyword(s):  
New Zealand ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Effectiveness of pandemic and seasonal influenza vaccine in preventing pandemic influenza A(H1N1)2009 infection in England and Scotland 2009-2010

2011 ◽  
Vol 16 (2) ◽  
Author(s):  
P Hardelid ◽  
D M Fleming ◽  
J McMenamin ◽  
N Andrews ◽  
C Robertson ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Seasonal Influenza ◽  
Seasonal Influenza Vaccine ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

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