scholarly journals Testicular stereological and histological changes in an experimental murine model of visceral leishmaniasis

2019 ◽  
Vol 24 (4) ◽  
pp. 86-94
Author(s):  
Erfan Yarahmadi ◽  
Ali Shalizar- Jalali ◽  
Nahid Jalallou ◽  
Minoo Shaddel ◽  
◽  
...  
2014 ◽  
Vol 40 (2) ◽  
pp. 436-443 ◽  
Author(s):  
Sanchita Datta ◽  
Supriya Khanra ◽  
Anindita Chakraborty ◽  
Syamal Roy ◽  
Madhumita Manna

1999 ◽  
Vol 43 (1) ◽  
pp. 172-174 ◽  
Author(s):  
Jean-Pierre Gangneux ◽  
Michael Dullin ◽  
Annie Sulahian ◽  
Yves Jean-Francois Garin ◽  
Francis Derouin

ABSTRACT In a murine model of Leishmania infantum visceral leishmaniasis, metronidazole, ketoconazole, fluconazole, itraconazole, and terbinafine were less effective than antimonial agents in reducing hepatic parasite load. Ketoconazole potentiated the effect of meglumine antimoniate reference therapy through its marked activity against spleen infection.


2014 ◽  
Vol 55 (3) ◽  
pp. J123-J129 ◽  
Author(s):  
Kazumi Hayama ◽  
Sanae Ishijima ◽  
Yoshiko Ono ◽  
Takayuki Izumo ◽  
Masayuki Ida ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-2
Author(s):  
Jorday Hernández-Aguas ◽  
José Luis Montiel-Hernández ◽  
Myriam A. De La Garza-Ramos ◽  
Rosa Velia Ruiz-Ramos ◽  
Erandi Escamilla García ◽  
...  

2018 ◽  
Vol 27 (1) ◽  
pp. 139-149 ◽  
Author(s):  
Snehalatha Diddi ◽  
Swarna Bale ◽  
Gauthami Pulivendala ◽  
Chandraiah Godugu

1987 ◽  
Vol 82 (3) ◽  
pp. 311-317 ◽  
Author(s):  
Zilton A. Andrade ◽  
Theomira Mauadie de Azevedo

In an attempt to establish an experimental model of acute schistosomiasis, sequential histological changes were investigated in the skin, lung, liver and spleen of mice infected with 30 or 100 cercariae of Schistosoma mansoni according to four sets of experiments: single infection, repeated infections, unisexual infection and infection in mice born from infected mothers. Animals were killed every other day from exposure up to 50 days after infection. Only mild, isolated, focal inflammatory changes were found before the appearance of mature eggs in the liver, even when repeated infections were made. Severe changes of reactive hepatitis and splenitis appeared suddenly when the first mature eggs were deposited, around the 37th to 42nd day after infection. The mature eggs induced lytic and coagulative necrosis of hepatocytes around them which was soon followed by dense infiltration of eosinophils. So, mature egg-induced lesions appeared as the major factors in the pathogenesis of acute schistosomiasis in mice. Mice born from infected mothers were apparently able to rapidly modulate the egg-lesions, forming early fibrotic granulomas. The murine model of acute schistosomiasis appeared adequate for the study of pathology and pathogenesis of acute schistosomiasis.


2018 ◽  
Vol 13 (10) ◽  
pp. 2247-2267 ◽  
Author(s):  
Julie Marchesan ◽  
Mustafa S. Girnary ◽  
Li Jing ◽  
Michael Zhe Miao ◽  
Shaoping Zhang ◽  
...  

2017 ◽  
Vol 73 (2) ◽  
pp. 448-451 ◽  
Author(s):  
Nathan P Wiederhold ◽  
Laura K Najvar ◽  
Rosie Jaramillo ◽  
Marcos Olivo ◽  
Jason Pizzini ◽  
...  

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