scholarly journals Rate of Distant Metastases on 18 F-FDG PET/CT at Initial Staging of Breast Cancer: Comparison of Women Younger and Older Than 40 Years

2016 ◽  
Vol 58 (2) ◽  
pp. 252-257 ◽  
Author(s):  
Vincent Lebon ◽  
Jean-Louis Alberini ◽  
Jean-Yves Pierga ◽  
Véronique Diéras ◽  
Nina Jehanno ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fdg Pet ◽  
Distant Metastases ◽  
Pet Ct ◽  
Fdg Pet Ct ◽  
Initial Staging

scholarly journals Dynamic FDG-PET/CT in the Initial Staging of Primary Breast Cancer: Clinicopathological Correlations

2019 ◽  
Vol 26 (2) ◽  
pp. 997-1006 ◽  
Author(s):  
Kornélia Kajáry ◽  
Zsolt Lengyel ◽  
Anna-Mária Tőkés ◽  
Janina Kulka ◽  
Magdolna Dank ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fdg Pet ◽  
Primary Breast Cancer ◽  
Pet Ct ◽  
Clinicopathological Correlations ◽  
Fdg Pet Ct ◽  
Initial Staging

scholarly journals FDG‐PET/CT Compared with Conventional Imaging in the Detection of Distant Metastases of Primary Breast Cancer

2011 ◽  
Vol 16 (8) ◽  
pp. 1111-1119 ◽  
Author(s):  
Naoki Niikura ◽  
Colleen M. Costelloe ◽  
John E. Madewell ◽  
Naoki Hayashi ◽  
Tse‐Kuan Yu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fdg Pet ◽  
Primary Breast Cancer ◽  
Distant Metastases ◽  
Conventional Imaging ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Diagnostic Performance of F18-FDG PET/CT in Male Breast Cancers Patients

Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 119
Author(s):  
Andra Piciu ◽  
Doina Piciu ◽  
Narcis Polocoser ◽  
Anita A. Kovendi ◽  
Iulia Almasan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fdg Pet ◽  
Distant Metastases ◽  
Lymph Node Involvement ◽  
Male Breast ◽  
Axillary Lymph ◽  
Pet Ct ◽  
Node Involvement ◽  
Male Patients ◽  
Fdg Pet Ct

Introduction: F18-FDG PET/CT is the most important hybrid imaging used in the diagnostic, staging, follow-up, and treatment evaluation response in cancer patients. However, it is well-known that in breast cancer the use of F18-FDG is not included in the first line protocol of initial diagnostic, both in female and male breast cancer patients. F18-FDG PET/CT is a valuable tool to provide information on extra-axillary lymph node involvement, distant metastases, and other occult primary cancers. This study assesses F18-FDG PET/CT systemic staging in male patients with diagnosed breast cancer and determines detection rates for unsuspected distant metastases and synchronous malignancies. Methods: We analyzed a number of 170 male patients with breast cancer, seen between 2000–2020, in a tertiary center. From this group, between 2013–2020 a number of 23 patients underwent F18-FDG PET/CT. Rates of upstaging were determined for each case and the detection of other primary malignancies was analyzed. Results: Median age of male breast cancer group was 61.3 y (range, 34–85 y), most had intraductal carcinoma (82.4%) and unsuspected distant metastases, which increased patient stage to IV, observed in 27%. In 4 out 23 patients (17.4%), F18-FDG PET/CT identified synchronous cancers (2 prostate cancers, 1 thyroid and 1 colon cancer). Conclusion: F18-FDG PET/CT is a valuable tool to provide information on extra-axillary lymph node involvement, distant metastases, and other occult primary cancers. Baseline F18-FDG PET/CT has a substantial impact on the initial staging and on clinical management in male breast patients and should be considered for use in newly diagnosed patients.

scholarly journals Clinical impact of 18F-FDG PET/CT on initial staging and therapy planning for breast cancer

2012 ◽  
Vol 4 (4) ◽  
pp. 693-698 ◽  
Author(s):  
BENGUL GUNALP ◽  
SEMRA INCE ◽  
ALPER OZGUR KARACALIOGLU ◽  
ASLI AYAN ◽  
OZDES EMER ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fdg Pet ◽  
Clinical Impact ◽  
Therapy Planning ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Initial Staging

scholarly journals Detection of distant metastases in patients with locally advanced breast cancer: role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography and conventional imaging with computed tomography scans

2017 ◽  
Vol 50 (4) ◽  
pp. 211-215 ◽  
Author(s):  
Almir Galvão Vieira Bitencourt ◽  
Wesley Pereira Andrade ◽  
Rodrigo Rodrigues da Cunha ◽  
Jorge Luis Fonseca de Acioli Conrado ◽  
Eduardo Nóbrega Pereira Lima ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Fdg Pet ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Distant Metastases ◽  
Conventional Imaging ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Abstract Objective: To evaluate positron emission tomography/computed tomography (PET/CT) and conventional imaging tests for the detection of distant metastases in patients with locally advanced breast cancer. Materials and methods: We included 81 patients with breast cancer who had undergone 18F-fluorodeoxyglucose (FDG) PET/CT before treatment. Conventional imaging included the following: bone scintigraphy; chest X-ray (in 14.5%) or CT (in 85.5%); and abdominal ultrasound (in 10.8%), CT (in 87.8%), or magnetic resonance imaging (in 1.4%). Histopathology and clinical/imaging follow-up served as reference. Results: Distant metastases were observed in nine patients (11.1%). On patient-based analysis, conventional imaging identified distant metastases in all 9 patients. In one patient, the initial 18F-FDG PET/CT failed to demonstrate bone metastases that was evident on bone scintigraphy. In two patients, the CT scan failed to show extra-axillary lymph node metastases that were identified on 18F-FDG PET/CT. There was no significant difference between 18F-FDG PET/CT and conventional imaging in terms of their sensitivity for the detection of distant metastases in patients with locally advanced breast cancer. Conclusion: This study showed that 18F-FDG PET/CT and conventional imaging with CT scans had similar sensitivity for the diagnosis of distant metastases in patients with locally advanced breast cancer. 18F-FDG PET/CT can add information about extra-axillary lymph node involvements.

scholarly journals Benefits and harms of implementing [18F]FDG-PET/CT for diagnosing recurrent breast cancer: a prospective clinical study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marianne Vogsen ◽  
Jeanette Dupont Jensen ◽  
Oke Gerke ◽  
Anne Marie Bak Jylling ◽  
Jon Thor Asmussen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Diagnostic Accuracy ◽  
Fdg Pet ◽  
Incidental Findings ◽  
Posterior Probability ◽  
Distant Metastases ◽  
Recurrent Breast Cancer ◽  
Pet Ct ◽  
Recurrent Breast ◽  
Fdg Pet Ct

Abstract Background [18F]-fluorodeoxyglucose-positron emission tomography/computed tomography ([18F]FDG-PET/CT) has been implemented sporadically in hospital settings as the standard of care examination for recurrent breast cancer. We aimed to explore the clinical impact of implementing [18F]FDG-PET/CT for patients with clinically suspected recurrent breast cancer and validate the diagnostic accuracy. Methods Women with suspected distant recurrent breast cancer were prospectively enrolled in the study between September 2017 and August 2019. [18F]FDG-PET/CT was performed, and the appearance of incidental benign and malignant findings was registered. Additional examinations, complications, and the final diagnosis were registered to reflect the clinical consequence of such findings. The diagnostic accuracy of [18F]FDG-PET/CT as a stand-alone examination was analyzed. Biopsy and follow-up were used as a reference standard. Results [18F]FDG-PET/CT reported breast cancer metastases in 72 of 225 women (32.0%), and metastases were verified by biopsy in 52 (52/225, 23.1%). Prior probability and posterior probability of a positive test for suspected metastatic cancer and incidental malignancies were 27%/85% and 4%/20%, respectively. Suspected malignant incidental findings were reported in 46 patients (46/225, 20.4%), leading to further examinations and final detection of nine synchronous cancers (9/225, 4.0%). These cancers originated from the lung, thyroid, skin, pancreas, peritoneum, breast, kidney, one was malignant melanoma, and one was hematological cancer. False-positive incidental malignant findings were examined in 37/225 patients (16.4%), mainly in the colon (n = 12) and thyroid gland (n = 12). Ten incidental findings suspicious for benign disease were suggested by [18F]FDG-PET/CT, and further examinations resulted in the detection of three benign conditions requiring treatment. Sensitivity, specificity, and AUC-ROC for diagnosing distant metastases were 1.00 (0.93–1.0), 0.88 (0.82–0.92), and 0.98 (95% CI 0.97–0.99), respectively. Conclusion [18F]FDG-PET/CT provided a high posterior probability of positive test, and a negative test was able to rule out distant metastases in women with clinically suspected recurrent breast cancer. One-fifth of patients examined for incidental findings detected on [18F]FDG-PET/CT were diagnosed with clinically relevant conditions. Further examinations of false-positive incidental findings in one of six women should be weighed against the high accuracy for diagnosing metastatic breast cancer. Trial registration Clinical.Trials.gov. NCT03358589. Registered 30 November 2017—Retrospectively registered, http://www.ClinicalTrials.gov

Additional value of F-18 FDG PET/CT for initial staging in breast cancer with clinically negative axillary nodes

2014 ◽  
Vol 145 (1) ◽  
pp. 137-142 ◽  
Author(s):  
Young Jin Jeong ◽  
Do-Young Kang ◽  
Hyun Jin Yoon ◽  
Hye Joo Son
Keyword(s):  
Breast Cancer ◽  
Fdg Pet ◽  
Axillary Nodes ◽  
Pet Ct ◽  
Additional Value ◽  
Fdg Pet Ct ◽  
Initial Staging

scholarly journals 18F-FDG PET/CT in breast cancer: Evidence-based recommendations in initial staging

Tumor Biology ◽  
2017 ◽  
Vol 39 (10) ◽  
pp. 101042831772828 ◽  
Author(s):  
Ana Paula Caresia Aroztegui ◽  
Ana María García Vicente ◽  
Soledad Alvarez Ruiz ◽  
Roberto Carlos Delgado Bolton ◽  
Javier Orcajo Rincon ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fdg Pet ◽  
Evidence Based ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Initial Staging
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