Epigenetic Activation of Ribosomal Cistrons in Chromatids of Acrocentric Chromosome 15 in Lung Cancer

2021 ◽  
Vol 55 (5) ◽  
pp. 491-497
Author(s):  
T. Lezhava ◽  
T. Buadze ◽  
N. Mikaia ◽  
T. Jokhadze ◽  
T. Sigua ◽  
...  
2003 ◽  
Vol 44 (1) ◽  
pp. 65 ◽  
Author(s):  
Hyun Jung Kee ◽  
Ju Hye Shin ◽  
Joon Chang ◽  
Kyung Young Chung ◽  
Dong Hwan Shin ◽  
...  

2015 ◽  
Vol 36 (11) ◽  
pp. 1275-1283 ◽  
Author(s):  
Xuemei Ji ◽  
Jiang Gui ◽  
Younghun Han ◽  
Paul Brennan ◽  
Yafang Li ◽  
...  

Author(s):  
David J. Wu ◽  
Carolyn Schanen

Chapter 17 discusses Chromosome 15, which is a small, satellited acrocentric chromosome that shows remarkable structural complexity in the proximal long arm, and which leads to a host of rearrangements that have been implicated in human genetic disorders. Interpretation of potential genotype–phenotype relationships for the unique and overlapping deletions and duplications that have been identified must consider key structural and functional elements that impact the complement of genes that are ultimately misexpressed.


JAMA ◽  
1966 ◽  
Vol 195 (6) ◽  
pp. 471-475 ◽  
Author(s):  
M. J. Krant

2016 ◽  
Vol 1 (13) ◽  
pp. 162-168
Author(s):  
Pippa Hales ◽  
Corinne Mossey-Gaston

Lung cancer is one of the most commonly diagnosed cancers across Northern America and Europe. Treatment options offered are dependent on the type of cancer, the location of the tumor, the staging, and the overall health of the person. When surgery for lung cancer is offered, difficulty swallowing is a potential complication that can have several influencing factors. Surgical interaction with the recurrent laryngeal nerve (RLN) can lead to unilateral vocal cord palsy, altering swallow function and safety. Understanding whether the RLN has been preserved, damaged, or sacrificed is integral to understanding the effect on the swallow and the subsequent treatment options available. There is also the risk of post-surgical reduction of physiological reserve, which can reduce the strength and function of the swallow in addition to any surgery specific complications. As lung cancer has a limited prognosis, the clinician must also factor in the palliative phase, as this can further increase the burden of an already compromised swallow. By understanding the surgery and the implications this may have for the swallow, there is the potential to reduce the impact of post-surgical complications and so improve quality of life (QOL) for people with lung cancer.


1999 ◽  
Vol 30 (1) ◽  
pp. 67-68
Author(s):  
M. R. V. Amarante ◽  
C. R. Lopes ◽  
J. E. Womack

1994 ◽  
Vol 8 (3) ◽  
pp. 507-532 ◽  
Author(s):  
Gary M. Strauss ◽  
Arthur T. Skarin
Keyword(s):  

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