scholarly journals Review on the Statistics of Cervical Cancer and its Biomarkers

2021 ◽  
Vol 8 (6) ◽  
pp. 72-78
Author(s):  
Aditi Prasad ◽  
Sruthi SS Kumar ◽  
Vaishnavi A
Keyword(s):  
Cervical Cancer ◽  
Cancer Detection ◽  
Statistical Data

The study's goal is to examine DNA-based nanobiosensors for cervical cancer detection, with an emphasis on statistical data on cervical cancer, which characterizes the problem of this illness impacting society and aids in better understanding the disease and its functioning in society affecting patients. From the point of diagnosis, numerous biomarkers for the detection of cervical cancer are also investigated.

The Pulse Wash Instrument A New Sampling Method for Uterine Cervical Cancer Detection

1986 ◽  
Vol 9 (4) ◽  
pp. 327-333
Author(s):  
Ingemar Näslund ◽  
Gert Auer ◽  
Folke Pettersson ◽  
Kerstin Sjövall
Keyword(s):  
Cervical Cancer ◽  
Cancer Detection ◽  
Sampling Method ◽  
Uterine Cervical Cancer

scholarly journals Cervical cytochemistry: a potential adjunct to cytomorphology for detection of abnormal cells in cervical cancer screening

2020 ◽  
Vol 10 (1) ◽  
pp. 1639-1644
Author(s):  
Indrani Krishnappa ◽  
Kalyani R. ◽  
Raja Parthiban ◽  
Abhishek Agrawal
Keyword(s):  
Cervical Cancer ◽  
Acid Phosphatase ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Cancer Detection ◽  
Pap Smear ◽  
Pap Test ◽  
Low Grade ◽  
Smear Examination ◽  
Intraepithelial Lesion

Background: Pap smear examination has been universally used as an effective screening tool for early detection of cervical carcinoma. The aim of this study was to assess the utility of Cervical Acid Phosphatase staining as an adjunct to routine Pap smear testing to improvethe sensitivity and specificity of routine Pap smear examination for cervical cancer detection. Materials and Methods: Cervical smears were taken from patients attending the gynecology department and a few cervical cancer screening programmes. One set of slides were alcohol fixed and stained with rapid pap stain and another set of slides were fixed in a special fixative and stained with Cervical Acid Phosphatase -Pap stain. The nuclear features of these Cervical Acid Phosphatase stained dysplastic cells was studied on Pap stain to diagnose cervical intraepithelial lesion/ malignancy. Results: Out of 489 cases included in the study 6 cases were diagnosed with intraepithelial lesion/ malignancy. On Cervical Acid Phosphatase -Pap stain 2 of the cases diagnosed as inflammatory smears on pap stain showed Cervical Acid Phosphatase positivity and thus were re evaluated. Mild nuclear atypia was observed in the Cervical Acid Phosphatase positive cells and these cases were diagnosed as Low grade squamous intraepithelial lesion and later biopsy proven to be Cervical intraepithelial Neoplasia I. Therefore Cervical Acid Phosphatase -Pap test was 100% sensitive and specific for cervical cancer detection. Conclusions: With 100% sensitivity Cervical Acid Phosphatase -Pap test satisfies the criteria of an efficient screening test.

Interval cancer audit and disclosure in cervical screening programmes: An international survey

2021 ◽  
pp. 096914132110623
Author(s):  
Patricia Fitzpatrick ◽  
Therese Mooney ◽  
Helen Byrne ◽  
Orla Healy ◽  
Noirin Russell ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Detection ◽  
Cervical Screening ◽  
Interval Cancer ◽  
Population Based ◽  
Audit Process ◽  
Detection Rates ◽  
Legal Cases ◽  
Cervical Cancers ◽  
International Comparative

Background Legal cases involving the National Cervical Screening Programme in Ireland following non-disclosure of an interval cervical cancer audit prompted this first international comparative survey of interval cervical cancer audit. Methods A survey of 22 international population-based cervical screening programmes was conducted, to determine if they undertook audit of invasive cervical cancers. Those countries/regions that perform reviews were asked (i) how the audit was undertaken, including how the reviews were performed and how they controlled for retrospective bias, (ii) how women are informed of the audit process and how their consent is obtained, and (iii) how audit results were disclosed to patients. Results Seventeen countries/regions invited completed the survey (77%); 65% (11/17) have an audit process for interval cervical cancers. Five perform individual patient reviews; three perform programme-wide review, with calculation of interval cancer detection rates; one routinely performs programme-wide review with calculation of interval cancer detection rates and offers individual reviews, and one routinely performs local hospital-level reviews. In the remaining country/region, hospital laboratories audit cancers, with a national audit process for all cervical cancers. Varying methodologies for retrospective cytology review were employed; four include control samples, with a ratio varying from 1:1 to 1:2. Three conduct a blinded review. Most countries/regions do not discuss interval cancer audit with participants and 3/11 (27.3%) inform women when a cervical cancer audit takes place. Disclosure is limited and variable. Conclusion The responses suggest that there is no consistent approach to audit of interval cervical cancers or to disclosure of audit results.

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