Skeletal muscle lactate dehydrogenase isozymes and fibre composition in viral, mycoplasma and bacterial infections in young and old men

1981 ◽  
Vol 41 (6) ◽  
pp. 551-556 ◽  
Author(s):  
G. Friman ◽  
N.-G. Ilbäck ◽  
L. Pilström
Keyword(s):  
Skeletal Muscle ◽  
Lactate Dehydrogenase ◽  
Bacterial Infections ◽  
Muscle Lactate ◽  
Lactate Dehydrogenase Isozymes ◽  
Fibre Composition ◽  
Old Men

scholarly journals THE DISTRIBUTION OF LACTATE DEHYDROGENASE ISOZYMES IN HUMAN SKELETAL MUSCLE FIBERS

1964 ◽  
Vol 12 (8) ◽  
pp. 608-614 ◽  
Author(s):  
M. VAN WIJHE ◽  
M. C. BLANCHAER ◽  
S. ST. GEORGE-STUBBS
Keyword(s):  
Skeletal Muscle ◽  
Lactate Dehydrogenase ◽  
Human Skeletal Muscle ◽  
Muscle Fibers ◽  
Isozyme Pattern ◽  
Electrophoretic Separation ◽  
Lactate Dehydrogenase Isozymes ◽  
Dehydrogenase Isozyme ◽  
Lactate Dehydrogenase Isozyme ◽  
Normal Human

A study of the distribution of lactate dehydrogenase isozymes in single fibers from normal human skeletal muscle is presented. The fibers were classified into red, intermediate and white types on histochemical grounds and their lactate dehydrogenase isozyme content assessed by electrophoretic separation in veronal buffered agar. The results generally agreed with previous homogenate studies on animal skeletal muscle, in that the white fibers contained almost exclusively isozymes IV and V, whereas red fibers were rich in isozymes I, II and III, but IV and V also appeared indigenous to these fibers. The intermediate fibers had an isozyme pattern combining the features of red and white fibers. The metabolic implications of these findings are discussed.

Effects of Early Severe Malnutrition on Heart and Skeletal Muscle Lactate Dehydrogenase

1976 ◽  
Vol 106 (9) ◽  
pp. 1235-1240 ◽  
Author(s):  
David Penney ◽  
Debra Anderson ◽  
John Dongas
Keyword(s):  
Skeletal Muscle ◽  
Lactate Dehydrogenase ◽  
Severe Malnutrition ◽  
Muscle Lactate

scholarly journals Affinity chromatography of lactate dehydrogenase on immobilized nucleotides

1973 ◽  
Vol 133 (3) ◽  
pp. 515-520 ◽  
Author(s):  
C. R. Lowe ◽  
P. D. G. Dean
Keyword(s):  
Skeletal Muscle ◽  
Lactate Dehydrogenase ◽  
Affinity Chromatography ◽  
Heart Muscle ◽  
Adenine Nucleotides ◽  
Free Solution ◽  
Muscle Lactate ◽  
Effects Of Ph ◽  
Influence Of Substrate ◽  
Lactate Dehydrogenase Isoenzymes

The interaction of two isoenzymes of lactate dehydrogenase from pig heart muscle (H4) and rabbit skeletal muscle (M4), with immobilized nucleotides was examined: the effects of pH and temperature on the binding of lactate dehydrogenase were studied with immobilized NAD+ matrices. The influence of substrate, product and sulphite on the binding of heart muscle lactate dehydrogenase to immobilized NAD+ was investigated. The interaction of both lactate dehydrogenase isoenzymes with immobilized pyridine and adenine nucleotides and their derivatives were measured. The effects of these parameters on the interaction of lactate dehydrogenase with immobilized nucleotides were correlated with the known kinetic and molecular properties of the enzymes in free solution.

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