AbstractWorkload-indexed blood pressure response (wiBPR) to exercise has been shown
to be superior to peak systolic blood pressure (SBP) in predicting mortality
in healthy men. Thus far, however, markers of wiBPR have not been evaluated
for athletes and the association with vascular function is unclear. We
examined 95 male professional athletes (26±5 y) and 30 male controls
(26±4 y). We assessed vascular functional parameters at rest and
wiBPR with a graded bicycle ergometer test and compared values for athletes
with those of controls. Athletes had a lower pulse wave velocity
(6.4±0.9 vs. 7.2±1.5 m/s, p=0.001) compared
to controls. SBP/Watt slope (0.34±0.13 vs.
0.44±0.12 mmHg/W), SBP/MET slope
(6.2±1.8 vs. 7.85±1.8 mmHg/MET) and peak
SBP/Watt ratio (0.61±0.12 vs.
0.95±0.17 mmHg/W) were lower in athletes than in
controls (p<0.001). The SBP/Watt and SBP/MET slope
in athletes were comparable to the reference values, whereas the peak
SBP/Watt-ratio was lower. All vascular functional parameters
measured were not significantly correlated to the wiBPR in either athletes
or controls. In conclusion, our findings indicate the potential use of the
SBP/Watt and SBP/MET slope in pre-participation screening of
athletes. Further, vascular functional parameters, measured at rest, were
unrelated to the wiBPR in athletes and controls.