Motivational Interviewing: Addressing Ambivalence to Improve Medication Adherence in Patients with Bipolar Disorder

2011 ◽  
Vol 33 (1) ◽  
pp. 8-14 ◽  
Author(s):  
Laura J. Laakso
2012 ◽  
Vol 172 (17) ◽  
pp. 1351
Author(s):  
Daniel H. Solomon ◽  
Maura Daly Iversen ◽  
Jeffrey N. Katz

Author(s):  
David J. Miklowitz ◽  
W. Edward Craighead

Whereas pharmacological interventions remain the primary treatment for bipolar disorder, adjunctive psychosocial interventions have the potential to increase adherence to medication regimens, decrease hospitalizations and relapses, improve quality of life, and enhance mechanisms for coping with stress. Controlled studies have established that individual, family, and group psychoeducation, designed to provide information to bipolar patients and their families about the disorder, its pharmacological treatment, and the treatments’ side effects, leads to lower rates of recurrence and greater adherence to pharmacological treatment among bipolar patients. Type 1 and 2 studies have evaluated cognitive behavioral therapy (CBT) as an ancillary treatment. These studies indicate that CBT is associated with better medication adherence and significantly fewer recurrences and/or rehospitalizations. One Type 1 study has evaluated the effectiveness of IPSRT (interpersonal and social rhythm therapy) for bipolar disorder. IPSRT demonstrated its greatest symptomatic effects during a maintenance treatment period, especially if bipolar patients had been successful in stabilizing their daily and nightly routines during an acute treatment period. Finally, four Type 1 studies in adult and pediatric patients have shown that marital/ family therapy may be effectively combined with pharmacotherapy to reduce recurrences and improve medication adherence and family functioning.


2017 ◽  
Vol 23 (5) ◽  
pp. 549-560 ◽  
Author(s):  
Susan Abughosh ◽  
Xin Wang ◽  
Omar Serna ◽  
Tara Esse ◽  
Amanda Mann ◽  
...  

2017 ◽  
Vol 47 (14) ◽  
pp. 2528-2539 ◽  
Author(s):  
A. H. Pakpour ◽  
A. Modabbernia ◽  
C.-Y. Lin ◽  
M. Saffari ◽  
M. Ahmadzad Asl ◽  
...  

BackgroundThe present research aimed to investigate the efficacy of a multifaceted intervention that included motivational interviewing (MI) and psychoeducation in improving medication adherence (MA) among patients with bipolar disorder (BD).MethodA multicenter, cluster randomized, observer-blind, controlled, parallel-group trial was conducted in ten academic centers in Iran. Patients with BD were randomly assigned to the experimental group (EXP; n = 136) or the usual care group (UC; n = 134). The EXP group received five sessions of MI and psychoeducation together with their family members. The primary outcome measure was changes in scores on the Medication Adherence Rating Scale from baseline to 6 months post-intervention. Other outcome measures included serum levels of mood stabilizers, clinical symptoms, quality of life, as well as measures of intention, beliefs about medicine, perceived behavioral control, automaticity, action and coping planning, and adverse reactions.ResultsMedication adherence improved over time in both groups, but patients in the EXP group improved more (baseline score: 6.03; score at the sixth month: 9.55) than patients in the UC group (baseline score: 6.17; score at the sixth month: 6.67). In addition, patients in the EXP group showed greater improvement than patients in the UC group in almost all secondary outcomes 6 months following the intervention.ConclusionsMultifaceted interventions that include motivational-interviewing and psychoeducation can significantly improve MA and clinical and functional outcomes in patients with BD.Trial Registration Number: The trial was registered with theClinicalTrials.gov database (NCT02241863) https://clinicaltrials.gov/ct2/show/NCT02241863


2005 ◽  
Vol 62 (12) ◽  
pp. 1311-1314 ◽  
Author(s):  
Carl J. Possidente ◽  
Kathryn K. Bucci ◽  
Walter J. McClain

2018 ◽  
Vol 4 (1) ◽  
pp. 25 ◽  
Author(s):  
Carol Blixen ◽  
Martha Sajatovic ◽  
David J. Moore ◽  
Colin Depp ◽  
Clint Cushman ◽  
...  

Objective: Individuals living with bipolar disorder (BD) have poorer management of chronic medical conditions such as hypertension (HTN), and worse treatment adherence than the general population. The study objective was to obtain information from patients with both BD and HTN that would inform the development of an m-Health intervention to improve medication adherence for poorly adherent individuals living with both these chronic illnesses.Methods: Focus group methodology was used to collect information from 13 participants on perceived barriers and facilitators to BD and HTN medication adherence, as well as feedback on the demonstration and use of a bidirectional text messaging system for medication reminders. Focus groups were audiotaped, transcribed verbatim, and analyzed using content analysis with an emphasis on dominant themes.Results: Forgetfulness was the most frequently mentioned barrier to taking antihypertensive medications, and decisions about taking them were often influenced by BD mood fluctuations and the burden of having to take “too many pills” for both chronic illnesses. Participants’ feedback about the use of a text-messaging system to help with medication adherence for BD and HTN was very positive, and their suggestions for modification were incorporated into a more customized system for testing in a Phase 2 trial.Conclusions: Our findings indicate that patient engagement in the development of an m-Health intervention has the potential to improve adherence with both BD and HTN medications in individuals with known sub-optimal adherence. Patient engagement in health care is essential if we are to optimize patient outcomes.


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