Lamina Cribrosa-Related Parameters Assessed by Optical Coherence Tomography for Prediction of Future Glaucoma Progression

2015 ◽  
Vol 41 (6) ◽  
pp. 806-813 ◽  
Author(s):  
Ho Seok Chung ◽  
Kyung Rim Sung ◽  
Jin Young Lee ◽  
Jung Hwa Na
Keyword(s):  
Optical Coherence Tomography ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Glaucoma Progression

scholarly journals Longitudinal assessment of optic nerve head changes using optical coherence tomography in a primate microbead model of ocular hypertension

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anita S. Y. Chan ◽  
Tin Aung Tun ◽  
John C. Allen ◽  
Myoe Naing Lynn ◽  
Sai Bo Bo Tun ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Ocular Hypertension ◽  
Optic Nerve Head ◽  
Structural Damage ◽  
Structural Changes ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Longitudinal Assessment ◽  
The Mean

Abstract In humans, the longitudinal characterisation of early optic nerve head (ONH) damage in ocular hypertension (OHT) is difficult as patients with glaucoma usually have structural ONH damage at the time of diagnosis. Previous studies assessed glaucomatous ONH cupping by measuring the anterior lamina cribrosa depth (LCD) and minimal rim width (MRW) using optical coherence tomography (OCT). In this study, we induced OHT by repeated intracameral microbead injections in 16 cynomolgus primates (10 unilateral; 6 bilateral) and assessed the structural changes of the ONH longitudinally to observe early changes. Elevated intraocular pressure (IOP) in OHT eyes was maintained for 7 months and serial OCT measurements were performed during this period. The mean IOP was significantly elevated in OHT eyes when compared to baseline and compared to the control eyes. Thinner MRW and deeper LCD values from baseline were observed in OHT eyes with the greatest changes seen between month 1 and month 2 of OHT. Both the mean and maximum IOP values were significant predictors of MRW and LCD changes, although the maximum IOP was a slightly better predictor. We believe that this model could be useful to study IOP-induced early ONH structural damage which is important for understanding glaucoma pathogenesis.

scholarly journals Three-dimensional High-speed Optical Coherence Tomography Imaging of Lamina Cribrosa in Glaucoma

Ophthalmology ◽  
2009 ◽  
Vol 116 (2) ◽  
pp. 214-222 ◽  
Author(s):  
Ryo Inoue ◽  
Masanori Hangai ◽  
Yuriko Kotera ◽  
Hideo Nakanishi ◽  
Satoshi Mori ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Three Dimensional ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Tomography Imaging ◽  
Optical Coherence Tomography Imaging

Prediction of Glaucoma Progression with Structural Parameters: Comparison of Optical Coherence Tomography and Clinical Disc Parameters

2019 ◽  
Vol 208 ◽  
pp. 19-29 ◽  
Author(s):  
Ramin Daneshvar ◽  
Adeleh Yarmohammadi ◽  
Reza Alizadeh ◽  
Sharon Henry ◽  
Simon K. Law ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Structural Parameters ◽  
Optical Coherence ◽  
Glaucoma Progression

Three-Dimensional Evaluation of the Lamina Cribrosa Using Spectral-Domain Optical Coherence Tomography in Glaucoma

2012 ◽  
Vol 53 (1) ◽  
pp. 198 ◽  
Author(s):  
Eun Ji Lee ◽  
Tae-Woo Kim ◽  
Robert N. Weinreb ◽  
Min Hee Suh ◽  
Myungjoo Kang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Three Dimensional ◽  
Lamina Cribrosa ◽  
Spectral Domain ◽  
Optical Coherence
Sign in / Sign up

Export Citation Format

Share Document