scholarly journals Author Response: Biomechanical Responses of Lamina Cribrosa to Intraocular Pressure Change Assessed by Optical Coherence Tomography in Glaucoma Eyes

2017 ◽  
Vol 58 (9) ◽  
pp. 3377 ◽  
Author(s):  
Harry A. Quigley
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Pressure Change ◽  
Lamina Cribrosa ◽  
Author Response ◽  
Optical Coherence ◽  
Biomechanical Responses

scholarly journals Biomechanical Responses of Lamina Cribrosa to Intraocular Pressure Change Assessed by Optical Coherence Tomography in Glaucoma Eyes

2017 ◽  
Vol 58 (9) ◽  
pp. 3376 ◽  
Author(s):  
Gema Rebolleda ◽  
Laura Díez-Álvarez ◽  
Victoria de Juan ◽  
Francisco J. Muñoz-Negrete
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Pressure Change ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Biomechanical Responses

scholarly journals Biomechanical Responses of Lamina Cribrosa to Intraocular Pressure Change Assessed by Optical Coherence Tomography in Glaucoma Eyes

2017 ◽  
Vol 58 (5) ◽  
pp. 2566 ◽  
Author(s):  
Harry Quigley ◽  
Karun Arora ◽  
Sana Idrees ◽  
Francisco Solano ◽  
Sahar Bedrood ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Pressure Change ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Biomechanical Responses

Simultaneous evaluation of the lamina cribosa position and choroidal thickness changes following deep sclerectomy

2018 ◽  
Vol 28 (6) ◽  
pp. 662-669 ◽  
Author(s):  
Gema Rebolleda ◽  
Victoria de Juan ◽  
Francisco J Muñoz-Negrete ◽  
Laura Díez-Álvarez
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Choroidal Thickness ◽  
Open Angle Glaucoma ◽  
Lamina Cribrosa ◽  
Enhanced Depth Imaging ◽  
Deep Sclerectomy ◽  
Optical Coherence ◽  
Choroidal Thickening ◽  
The Mean

Purpose: To assess the changes in peripapillary and macular choroidal thickness, and in the lamina cribrosa position following deep sclerectomy. Methods: Prospective study, including 39 eyes with open-angle glaucoma following deep sclerectomy. Choroidal thickness was automatically measured using swept-source optical coherence tomography at four peripapillary locations (superior, temporal, inferior, and nasal) and at the macular area in nine fields plotted with Early Treatment Diabetic Retinopathy Study grid. Optic nerve head was evaluated by Spectralis optical coherence tomography with enhanced depth imaging technology. All measurements were performed preoperatively and at 1 week and 2 months after surgery. Results: The mean intraocular pressure significantly decreased 1 week and 2 months after surgery ( p < 0.001). A significant peripapillary choroidal thickening was observed at all locations 1 week postoperatively ( p ≤ 0.002) and in the temporal quadrant 2 months after surgery ( p = 0.027). There was a significant thickening in all macular choroidal thickness measurements at 1 week ( p < 0.001) and 2 months ( p < 0.05), except at subfoveal and inner nasal locations. The mean peripapillary and macular choroid thickness was 22.8% and 19.7% at 1 week and 6.2% and 7.8% at 2 months, respectively. A significant forward lamina cribrosa displacement occurred at every postoperative stage ( p < 0.001). Multivariate analysis showed a significant correlation between the magnitude of intraocular pressure reduction and the anterior lamina cribrosa movement (0.623, p = 0.000) and a negative correlation between the intraocular pressure change and the mean peripapillary and macular choroidal thickening (−0.527, p = 0.002; −0.568, p = 0.002, respectively). Conclusion: There was a significant reversal lamina cribrosa displacement measured from Bruch’s membrane opening reference despite a significant peripapillary choroidal thickening following deep sclerectomy. Both findings were significantly correlated with the change in intraocular pressure

scholarly journals Visualization of the Lamina Cribrosa of Sclera Using Optical Coherence Tomography. The Opportunities and Prospects for Diagnostics (Review)

2019 ◽  
Vol 16 (2) ◽  
pp. 159-162
Author(s):  
V. V. Kurenkov ◽  
V. S. Klyuganov ◽  
N. V. Kuznetsova ◽  
K. V. Chinenova ◽  
M. E. Konovalov ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Connective Tissue ◽  
Study Groups ◽  
Lamina Cribrosa ◽  
Nerve Fibers ◽  
Small Sample ◽  
Optical Coherence ◽  
Methods Of Treatment ◽  
Standard Software

The lamina cribrosa of the sclera is a multilayer structure consisting of layers of connective tissue represented by collagen of various types. The ratio of collagen fibers I, II and IV types, as well as elastin protein provide support and elastic properties of the lamina cribrosa. Increased intraocular pressure on the background of involutional changes in the composition of the connective tissue of the lamina cribrosa leads to deformation of the latter, compression of nerve fibers passing through the holes in the lamina cribrosa and violation of the axoplasmic current. Modern high-resolution optical coherence tomographs allow to visualize the confines of the lamina cribrosa, and the standard software integrated into each device allows to measure the parameters of the lamina cribrosa. The visualization of the lamina cribrosa in the early stages of glaucoma due to the severity of the pre-laminar tissue and the screening of the surface of the lamina cribrosa is still a problem. The presented review contains the results of studies of various ophthalmologists from different countries. The dependence of such parameters of the lamina cribrosa as depth, thickness, angle of inclination and curvature on the increased of intraocular pressure and the stage of glaucoma process was found. These studies confirm the possibility of visualization of the lamina cribrosa, open prospects in the study of the pathogenesis of glaucoma and expand the possibilities in the search for new methods of treatment of glaucoma optical neuropathy based on pathogenetic aspects. However, a small number of articles on this subject, found in the literature, and a small sample of the study groups in most works require further study of the visualization of the lamina cribrosa using optical coherence tomography.

Author response for "Utility of optical coherence tomography in the diagnosis and management of optic neuropathy in patients with fibrous dysplasia"

2020 ◽  
Author(s):  
Kristen S. Pan ◽  
Edmond J. FitzGibbon ◽  
Susan Vitale ◽  
Janice S. Lee ◽  
Michael T. Collins ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fibrous Dysplasia ◽  
Optic Neuropathy ◽  
Author Response ◽  
Optical Coherence ◽  
Diagnosis And Management

scholarly journals The Use of Anterior-Segment Optical-Coherence Tomography for the Assessment of the Iridocorneal Angle and Its Alterations: Update and Current Evidence

2021 ◽  
Vol 10 (2) ◽  
pp. 231
Author(s):  
Giacinto Triolo ◽  
Piero Barboni ◽  
Giacomo Savini ◽  
Francesco De Gaetano ◽  
Gaspare Monaco ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Clinical Relevance ◽  
Anterior Segment ◽  
Angle Closure ◽  
Current Evidence ◽  
Optical Coherence ◽  
Iridocorneal Angle ◽  
Wide Range

The introduction of anterior-segment optical-coherence tomography (AS-OCT) has led to improved assessments of the anatomy of the iridocorneal-angle and diagnoses of several mechanisms of angle closure which often result in raised intraocular pressure (IOP). Continuous advancements in AS-OCT technology and software, along with an extensive research in the field, have resulted in a wide range of possible parameters that may be used to diagnose and follow up on patients with this spectrum of diseases. However, the clinical relevance of such variables needs to be explored thoroughly. The aim of the present review is to summarize the current evidence supporting the use of AS-OCT for the diagnosis and follow-up of several iridocorneal-angle and anterior-chamber alterations, focusing on the advantages and downsides of this technology.

Author Response to Diagnostic Characteristics of B-Scan Swept-Source Optical Coherence Tomography for Patients With Polypoidal Choroidal Vasculopathy

Retina ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ai Fujita ◽  
Keiko Kataoka ◽  
Jun Takeuchi ◽  
Yuyako Nakano ◽  
Etsuyo Horiguchi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Polypoidal Choroidal Vasculopathy ◽  
Author Response ◽  
Optical Coherence ◽  
Swept Source ◽  
Diagnostic Characteristics ◽  
Choroidal Vasculopathy
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