Effect of Cimetidine on Gastrointestinal Symptoms in Patients Taking Nonsteroidal Anti-inflammatory Drugs:A large Double-blind Placebo Controlled Study

1994 ◽  
Vol 23 (4) ◽  
pp. 177-182 ◽  
Author(s):  
H. E. Rugstad ◽  
K. E. Giercksky ◽  
G. Husby ◽  
I. Holme
Keyword(s):  
Gastrointestinal Symptoms ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Anti Inflammatory

RETRACTED: A Randomized, Double-Blind, Placebo-Controlled Study Assessing the Anti-inflammatory Effects of Ketamine in Cardiac Surgical Patients

2006 ◽  
Vol 20 (2) ◽  
pp. 217-222 ◽  
Author(s):  
Cristian Bartoc ◽  
Robert J. Frumento ◽  
Maya Jalbout ◽  
Elliott Bennett-Guerrero ◽  
Evelyn Du ◽  
...  
Keyword(s):  
Surgical Patients ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Anti Inflammatory

scholarly journals USING BREWER’S YEAST AND GINGER IN THE MANAGEMENT OF CONSTIPATION-PREDOMINANT IRRITABLE BOWEL SYNDROME: A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL

2019 ◽  
pp. 372-376 ◽  
Author(s):  
ZAINAB G AL-JASSIM
Keyword(s):  
Irritable Bowel Syndrome ◽  
Controlled Trial ◽  
Gastrointestinal Symptoms ◽  
Abdominal Distention ◽  
Controlled Study ◽  
Brewer’S Yeast ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Brewer's Yeast ◽  
Irritable Bowel

Objective: The objective of the present study is to confirm and/or prove the beneficial outcomes from using Brewer’s yeast and Ginger in constipation-predominant irritable bowel syndrome (IBS-C) subjects compared to placebo. Methods: A total of 45 patients suffering from IBS-C were enrolled in a double-blind placebo-controlled study as defined by Rome III criteria. Parallel groups were randomly assigned in this study: A placebo group, Brewer’s yeast group, and ginger group, taken daily for 20 days. IBS severity scale and visual analog scale for IBS (VAS-IBS) were used to assess the severity of pain, abdominal distention, and constipation (IBS-C) subjects. The data were measured at 3 times: At 0 time (T0), after 10 days of treatment (T10), and after 20 days of treatment (T20) for the three treatment groups. Results: Intragroup analysis showed a clinically significant reduction in the symptoms of abdominal pain, distention, and constipation, in the Brewer’s yeast group compared to placebo after the 20 days of the study. There was also a significant reduction of abdominal distention and constipation symptoms in the ginger group throughout the study. Conclusion: This study reveals the beneficial effects of Brewer’s yeast and ginger in reducing troublesome gastrointestinal symptoms in subjects with IBS-C and holds the promise to use them in IBS-C patient.

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