Risk Factors for Graft Occlusion after Coronary Artery Bypass Grafting

1995 ◽  
Vol 29 (2) ◽  
pp. 63-69 ◽  
Author(s):  
Jan Eritsland ◽  
Harald Arnesen ◽  
Nils B. Fjeld ◽  
Knut Grønseth ◽  
Michael Abdelnoor
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Graft Occlusion ◽  
Artery Bypass Grafting

Haemostatic Factors and Inhibitors and Coronary Artery Bypass Grafting: Preoperative Alterations and Relations to Graft Occlusion

1994 ◽  
Vol 72 (03) ◽  
pp. 335-342 ◽  
Author(s):  
Elisabeth Moor ◽  
Anders Hamsten ◽  
Margareta Blombäck ◽  
Istvan Herzfeld ◽  
Björn Wiman ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Factor Vii ◽  
Bypass Grafting ◽  
Graft Occlusion ◽  
Artery Bypass Grafting ◽  
The Third ◽  
Haemostatic Factors

SummaryGraft closure remains a major problem after coronary artery bypass surgery. While a number of graft characteristics influencing the risk of occlusion have been defined, the role of haemostatic factors and inhibitors has not been studied in detail. The present study examined the time course of changes in blood coagulation and fibrinolytic function after coronary artery bypass grafting in 20 consecutive patients. Pre- and postoperative determinations of haemostatic factors and inhibitors were also related to the presence of graft occlusion assessed by angiography at three months after surgery. A broad panel of haemostatic tests was used preoperatively, on the first, third and eight postoperative days, and at three months after surgery. A particular emphasis was placed on fibrinogen, factor VII activity, von Willebrand factor (vWF), plasminogen activator inhibitor-1 (PAI-1) activity, anticoagulant proteins C and S, thrombin-antithrombin complex and D-dimer. A marked activation of the coagulation cascade was noted postoperatively along with enhanced degradation of cross-linked fibrin. The degree of activation of blood coagulation and fibrinolysis differed widely between individuals and appeared to relate only partly to the acute phase reaction produced by the surgical trauma. Preoperative values of haemostatic factors and inhibitors showed fairly weak associations with the levels of postoperative determinations. Basal tPA and factor VIII levels, fibrinogen and TAT concentrations on the third and eighth postoperative day, and factor VII amidolytic activity on the third postoperative day differed (p <0.05) between patients with and without occluded grafts at reangiography. Accordingly, combined pre- and postoperative assessment of haemostatic function may contribute to the identification of individuals at risk for early graft closure after coronary artery bypass grafting.

Mortality Risk Factors in Chronic Renal Failure Patients after Coronary Artery Bypass Grafting

Renal Failure ◽  
2007 ◽  
Vol 29 (7) ◽  
pp. 823-828 ◽  
Author(s):  
Beril Akman ◽  
Ayse Bilgic ◽  
Gulsah Sasak ◽  
Siren Sezer ◽  
Atilla Sezgin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Failure ◽  
Coronary Artery ◽  
Chronic Renal Failure ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Mortality Risk ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

scholarly journals Pleiotropic Effects of Acetylsalicylic Acid after Coronary Artery Bypass Grafting—Beyond Platelet Inhibition

2021 ◽  
Vol 10 (11) ◽  
pp. 2317
Author(s):  
Dominika Siwik ◽  
Magdalena Gajewska ◽  
Katarzyna Karoń ◽  
Kinga Pluta ◽  
Mateusz Wondołkowski ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Acetylsalicylic Acid ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Platelet Inhibition ◽  
Pleiotropic Effects ◽  
Bypass Grafting ◽  
Graft Occlusion ◽  
Artery Bypass Grafting

Acetylsalicylic acid (ASA) is one of the most frequently used medications worldwide. Yet, the main indications for ASA are the atherosclerosis-based cardiovascular diseases, including coronary artery disease (CAD). Despite the increasing number of percutaneous procedures to treat CAD, coronary artery bypass grafting (CABG) remains the treatment of choice in patients with multivessel CAD and intermediate or high anatomical lesion complexity. Taking into account that CABG is a potent activator of inflammation, ASA is an important part in the postoperative therapy, not only due to ASA antiplatelet action, but also as an anti-inflammatory agent. Additional benefits of ASA after CABG include anticancerogenic, hypotensive, antiproliferative, anti-osteoporotic, and neuroprotective effects, which are especially important in patients after CABG, prone to hypertension, graft occlusion, atherosclerosis progression, and cognitive impairment. Here, we discuss the pleiotropic effects of ASA after CABG and provide insights into the mechanisms underlying the benefits of treatment with ASA, beyond platelet inhibition. Since some of ASA pleiotropic effects seem to increase the risk of bleeding, it could be considered a starting point to investigate whether the increase of the intensity of the treatment with ASA after CABG is beneficial for the CABG group of patients.

scholarly journals Risk factors for the return of mitral regurgitation after coronary artery bypass grafting and mitral valve reconstruction in patients with ischemic cardiomyopathy

2021 ◽  
Author(s):  
Iuliia Kareva ◽  
Vidadiue Efendiev ◽  
Alexey Nesmachnyy ◽  
Sardor Rakhmonov ◽  
Alexander Chernyavskiy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Mitral Insufficiency ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Background and Aim: We aimed to identify risk factors for recurrent mitral regurgitation in two surgical treatment groups: isolated coronary artery bypass grafting (CABG) and CABG combined with mitral valve (MV) repair in patients with moderate ischemic mitral regurgitation (IMR). Methods: A single-centre, prospective, randomised study, which included 76 patients with ICM and moderate mitral regurgitation (MR). Study included two groups: isolated CABG and CABG with MV repair (MVR). Isolated annuloplasty was used to correct mitral insufficiency in the CABG + MVR group. Results: Isolated CABG or CABG combined with MVR in patients with ICM does not lead to a statistically significant decreasing of MR in the long-term period compared to baseline values. However, in one year after surgery, the degree of MR after combined surgery is lower than the initial values. The identification of predictors of the progression of IMR in ICM made it possible to determine the threshold values for the effectiveness of MVR, and the assessment of echocardiographic predictors for annuloplasty helps to choose the right surgical tactic of patients. Conclusions: Coronary revascularization with surgical of IMR in patients with ICM does not increase the number of complications in the early postoperative period compared to the group of isolated CABG. In patients with ICM and moderate MR after isolated CABG, the progression of MR (MR of the 3rd degree, initially 0%, after 12 months 31%, after 36 months 71%; p <0.001) was observed even with an initially moderate expansion of the fibrous ring of the MV.

Risk Factors for Late Stroke After Coronary Artery Bypass Grafting

2005 ◽  
Vol 14 (12) ◽  
pp. 48-49
Author(s):  
T. Schachner ◽  
A. Zimmer ◽  
G. Nagele ◽  
G. Laufer ◽  
J. Bonatti
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Prevalence of leg wound complications after coronary artery bypass grafting: determination of risk factors

1999 ◽  
Vol 8 (3) ◽  
pp. 149-153 ◽  
Author(s):  
MA Goldsborough ◽  
MH Miller ◽  
J Gibson ◽  
S Creighton-Kelly ◽  
CA Custer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Wound Complications ◽  
Bypass Grafting ◽  
Community Settings ◽  
Artery Bypass Grafting

BACKGROUND: The reported prevalence of leg wound complications after coronary artery bypass grafting is 2% to 24%. Decreased length of hospital stay for patients who have this surgical procedure poses new care requirements in both acute care and community settings. OBJECTIVE: To determine the prevalence of postoperative leg wound complications in patients undergoing coronary artery bypass grafting and the risk factors associated with these complications. METHOD: In this prospective, observational study, 547 consecutive patients who had coronary artery bypass grafting alone or in combination with other cardiac surgical procedures were examined for evidence of leg wound complications each day after surgery during hospitalization. After discharge, problems were detected by home care nurses. RESULTS: The prevalence of leg wound complications was 6.8%. Factors significant by multiple logistic regression included preoperative hospitalization, use of an Ace elastic bandage in the operating room, the length of time the leg incision remained open in the operating room, and administration of nicardipine intravenously in the intensive care unit. Odds ratios were calculated for each variable. Premorbid factors such as diabetes or peripheral vascular disease were not predictive of complications. On average, most problems occurred on postoperative day 10, when many patients were at home. CONCLUSIONS: The results highlight the need to detect complications early, in both the hospital and the community settings. The determination of factors related to poor outcomes may assist clinicians in improving healthcare delivery.

Risk Factors and Outcomes in Redo Coronary Artery Bypass Grafting

2020 ◽  
Vol 29 (3) ◽  
pp. 384-389 ◽  
Author(s):  
Michele Gallo ◽  
Jaimin R. Trivedi ◽  
Gretel Monreal ◽  
Brian L. Ganzel ◽  
Mark S. Slaughter
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Artery Bypass Grafting
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