Neuromyelitis optica spectrum disorder complicated with Sjogren syndrome successfully treated with tocilizumab: A case report

2013 ◽  
Vol 26 (2) ◽  
pp. 294-296 ◽  
Author(s):  
Toshihiko Komai ◽  
Hirofumi Shoda ◽  
Kenichi Yamaguchi ◽  
Keiichi Sakurai ◽  
Mihoko Shibuya ◽  
...  
Medicine ◽  
2020 ◽  
Vol 99 (45) ◽  
pp. e23029
Author(s):  
Wei Zheng ◽  
Xiaoping Liu ◽  
Xiujuan Hou ◽  
Yuelan Zhu ◽  
Taotao Zhang ◽  
...  

2013 ◽  
Vol 53 (9) ◽  
pp. 695-700 ◽  
Author(s):  
Yasutaka Iwanaga ◽  
Shintaro Hayashi ◽  
Nobutoshi Kawamura ◽  
Yasumasa Ohyagi ◽  
Jun-ichi Kira

2014 ◽  
Vol 20 (10) ◽  
pp. 1413-1416 ◽  
Author(s):  
Jun Sawada ◽  
Ryosuke Orimoto ◽  
Tatsuro Misu ◽  
Takayuki Katayama ◽  
Hitoshi Aizawa ◽  
...  

A woman with Sjögren syndrome manifesting as aphasia with a left deep cerebral white matter lesion tested positive for anti-aquaporin 4 (AQP4) antibody. Open biopsy of the lesion revealed active demyelination with edematous changes and the preservation of most axons, indicating a non-necrotic demyelinating lesion. Immunostaining for AQP4 was diffusely lost, whereas the loss of glial fibrillary acidic protein immunostaining was limited but with highly degenerated astrocytic foot processes in perivascular areas. These results suggested neuromyelitis optica spectrum disorder (NMOSD) pathology rather than Sjögren-related vasculitis. Only cerebral cortical symptoms with a cerebral white matter lesion could be observed in NMOSDs.


2019 ◽  
Vol 30 ◽  
pp. vi131
Author(s):  
Piyakarn Watcharenwong ◽  
Touch Ativitavas ◽  
Thanate Dajsakdipon ◽  
Charungthai Dejthevaporn

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