Toxicological Profile for Polycyclic Aromatic Hydrocarbons, U.S. Department of Health & Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Washington, D.C., August, 1985

1999 ◽  
Vol 18 (2) ◽  
pp. 141-147 ◽  
2001 ◽  
Vol 17 (2) ◽  
pp. 41-62 ◽  
Author(s):  
Obaid M Faroon ◽  
Sam Keith ◽  
Dennis Jones ◽  
Christopher De Rosa

As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These profiles comprehensively summarize toxicological and environmental information. This article constitutes the release of an important section of the Toxicological profile for polychlorinated biphenyls [ATSDR. 2000: Toxicological profile for polychlorinated biphenyls. Atlanta, GA: US Department of Health and Human Services, Agency for Toxic Substances and Disease Registry.] into the scientific literature. This article focuses on the carcinogenic effects of this group of synthetic organic chemicals (polychlorinated biphenyls) in humans and animals. Information on other health effects, toxicokinetics, mechanisms of toxicity, biomarkers, interactions, chemical and physical properties, potential for human exposure, and regulations and advisories is detailed in the profile.


2006 ◽  
Vol 22 (10) ◽  
pp. 423-493 ◽  
Author(s):  
Nickolette Roney ◽  
Mark Osier ◽  
Sari J. Paikoff ◽  
Cassandra V. Smith ◽  
Malcolm Williams ◽  
...  

As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites, which have the greatest public health impact. These profiles comprehensively summarise toxicological and environmental information. This article constitutes the release of portions of the Toxicological Profile for Zinc. The primary purpose of this article is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of zinc. It contains descriptions and evaluations of toxicological studies and epidemiological investigations, and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic data to public health. Toxicology and Industrial Health 2006; 22: 423-493.


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