Effects of In-Center Resistance Training in End-Stage Renal Disease: A Pilot Study

ABSTRACT Background: Patients with end-stage renal disease are sedentary, frail, and have low functional ability (FA) compared to healthy age-matched controls. The purpose of this study was to examine the effects of an intradialytic, supervised, 8-week resistance training (RT) program on strength (ST), FA, and quality of life (QOL) in a sample of patients with end-stage renal disease. Methods: Twenty hemodialysis patients were randomized to an exercise (E, n = 12) or control (C, n = 8) group. Patients randomized to E received intradialytic RT immediately before and during treatment, 3 d per week for 8 weeks. Patients randomized to C received usual care and no exercise. ST and FA were assessed at baseline and at 4 and 8 weeks with manual muscle testing and the Short Physical Performance Battery. QOL was assessed at baseline and 8 weeks with the 36-item Short Form Health Survey (SF-36). Mixed factorial ANOVAs were used to determine the effects of RT on ST, FA, and QOL. Results: Significant interactions were found for ST for the right (p = 0.006) and left (p = 0.008) gastrocnemius, right quadriceps (p = 0.003), right (p = 0.005) and left (p = 0.004) hamstrings, and right adductor (p = 0.020). ST improved for E but not C across time (p < 0.05). Significant time effects for FA were found for chair (p = 0.001) and total (p = 0.008) SPPB scores but were not different between groups (p > 0.05). Similar effects were found for the physical performance component of the SF-36 (p = 0.023). Conclusion: A supervised 8-week, intradialytic RT program improved lower body ST in patients with end-stage renal disease; however, these improvements did not impact FA or QOL.

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Progressive Resistance Training in End-Stage Renal Disease: Systematic Review

American Journal of Nephrology ◽

10.1159/000446847 ◽

2016 ◽

Vol 44 (1) ◽

pp. 32-45 ◽

Cited By ~ 20

Author(s):

Danwin Chan ◽

Birinder S. Cheema

Keyword(s):

Systematic Review ◽

Resistance Training ◽

Renal Disease ◽

End Stage Renal Disease ◽

Protein Energy Malnutrition ◽

Control Period ◽

Progressive Resistance Training ◽

Stage Renal Disease ◽

End Stage ◽

Progressive Resistance

Background: This systematic review provides an overview of the extant literature on progressive resistance training (PRT) in patients with end-stage renal disease (ESRD) and outlines recommendations for future trials. Methods: A systematic review of all published literature evaluating the chronic (>6 weeks) application of PRT in patients with ESRD using electronic databases. Results: The search yielded 16 clinical trials, including 11 randomized controlled trials (RCT), 4 uncontrolled trials and one trial involving a within-subjects control period plus RCT. RCT quality, assessed via the CONSORT statement, ranged from low (4/10) to high (10/10) with a mean score of 7.3/10; 7/11 RCT had a quality score ≥7.5. All trials evaluated chronic adaptation to PRT across a range of important outcomes. PRT can induce muscle hypertrophy and improve aspects of physical functioning and health-related quality of life in ESRD. There is preliminary evidence that PRT may reduce protein-energy malnutrition and cardiovascular disease risk factors, including C-reactive protein, total cholesterol, triglyceride, and measures of insulin resistance in patients with or at-risk of comorbid type 2 diabetes. The evidence base for PRT adapting some of the endpoints investigated to date remains inconsistent (e.g. physical performance tests, obesity outcomes), and many other pertinent clinical outcomes remain to be investigated. Conclusion: RCT are required to investigate a range of novel research questions related to the benefits and application of PRT in this cohort and its patient subgroups (e.g. diabetes, depression, dyslipidemia, etc.). Future studies must be of high methodological quality to inform clinical practice guidelines.

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Effects of resistance training on hepcidin levels and iron bioavailability in older individuals with end-stage renal disease: A randomized controlled trial

Experimental Gerontology ◽

10.1016/j.exger.2020.111017 ◽

2020 ◽

Vol 139 ◽

pp. 111017

Author(s):

Sting Ray Gouveia Moura ◽

Hugo Luca Corrêa ◽

Rodrigo Vanerson Passos Neves ◽

Cláudio Avelino Rodrigues Santos ◽

Luiz Sinésio Silva Neto ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Resistance Training ◽

Renal Disease ◽

End Stage Renal Disease ◽

Controlled Trial ◽

Iron Bioavailability ◽

Older Individuals ◽

Randomized Controlled ◽

Stage Renal Disease ◽

End Stage

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Development, feasibility, and efficacy of a customized exercise device to deliver intradialytic resistance training in patients with end stage renal disease: Non-randomized controlled crossover trial

Hemodialysis International ◽

10.1111/hdi.12432 ◽

2016 ◽

Vol 20 (4) ◽

pp. 650-660 ◽

Cited By ~ 8

Author(s):

Danwin Chan ◽

Simon Green ◽

Maria Fiatarone Singh ◽

Robert Barnard ◽

Birinder S. Cheema

Keyword(s):

Resistance Training ◽

Renal Disease ◽

End Stage Renal Disease ◽

Crossover Trial ◽

Randomized Controlled ◽

Stage Renal Disease ◽

End Stage

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PUK18 A MULTICENTRE STUDY OF RENAL TRANSPLANT PATIENTS USING THE SF-36 AND THE END STAGE RENAL DISEASE SYMPTOM CHECK-LIST (ESRD-SCL)

Value in Health ◽

10.1016/s1098-3015(10)63785-0 ◽

2006 ◽

Vol 9 (6) ◽

pp. A390

Author(s):

T Ortega ◽

F Ortega ◽

C Valdés

Keyword(s):

Renal Transplant ◽

Renal Disease ◽

Multicentre Study ◽

End Stage Renal Disease ◽

Check List ◽

Transplant Patients ◽

Sf 36 ◽

Symptom Check List ◽

Stage Renal Disease ◽

End Stage

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KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIS YANG MENJALANI HEMODIALISIS DI RSUD CHASAN BOESOIRIE TERNATE

Kieraha Medical Journal ◽

10.33387/kmj.v1i2.1726 ◽

2019 ◽

Vol 1 (2) ◽

Author(s):

FATHUL RISKY

Keyword(s):

Quality Of Life ◽

Kidney Disease ◽

Renal Disease ◽

End Stage Renal Disease ◽

Short Form ◽

Primary Data ◽

P Value ◽

Stage Renal Disease ◽

End Stage

Introduction. Chronic kidney disease (CKD) as a result of structural and functional renal failure has a high progressivity leading to an end stage renal disease (ESRD), thus a therapy is needed to replace the renal function such as hemodialysis. Long term hemodialysis therapy affects many aspects of life and degrading the quality of life of the patient. Method. This cross-sectional study was conducted at Chasan Boesoirie Hospital, Ternate. Primary data, such as socio-demography were taken through history taking and medical records. Quality of life was assessed using Kidney Disease Quality of Life - Short Form (KDQOL-SF)-36 TM which has been used to measure quality of life of patients undergoing hemodialysis. Results. From this study a sample of 77 patients was obtained, of which 41 were male (53.25%) and 36 were female (46.75%). Of the three quality of life components assessed, KDCS components were 78.65 ± 13.39; the MCS component 54.67 ± 7.53; and PCS components 42.47 ± 7.76. Conclusions. From the results of the study it was found that the highest KDQOL-36TM score was obtained for the kidney disease component (KDCS), then the mental health component (MCS), and the lowest score for the physical health component (PCS). Of all the variables hypothesized to affect the quality of life of kidney failure patients undergoing hemodialis, not a single variable was found to be significantly affected (P value> 0.05).Keywords: end-stage renal disease, hemodialysis, quality of life.

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Quality of Life in Predialysis End-Stage Renal Disease Patients at the Initiation of Dialysis Therapy

Peritoneal Dialysis International ◽

10.1177/089686080002000113 ◽

2000 ◽

Vol 20 (1) ◽

pp. 69-75 ◽

Cited By ~ 41

Author(s):

◽

Johanna C. Korevaar ◽

Maarten A.M. Jansen ◽

Maruschka P. Merkus ◽

Friedo W. Dekker ◽

...

Keyword(s):

Quality Of Life ◽

Renal Disease ◽

End Stage Renal Disease ◽

Case Mix ◽

Dialysis Therapy ◽

Sf 36 ◽

Initiation Of Dialysis ◽

Stage Renal Disease ◽

End Stage

Objective To assess health-related quality of life (QL) in a group of Dutch predialysis end-stage renal disease (ESRD) patients prior to the initiation of dialysis, and to compare QL between patients with different intended initial dialysis treatments. Design In a prospective cohort study, demographic, clinical, and QL data were obtained from Dutch adult patients who were consecutively enrolled from 27 different centers 0 – 4 weeks prior to the beginning of their chronic dialysis treatment. Patients Of the 301 patients who completed the QL questionnaires (of a possible 337 enrolled patients), 152 intended to start with hemodialysis (pre-HD) and 149 patients with peritoneal dialysis (pre-PD). Main Outcome Measure Perceived QL of pre-HD and pre-PD patients. Quality of life was assessed with two generic health assessment instruments: the SF-36 and the EuroQol. Results After correction for group differences, pre-HD patients scored consistently, but not significantly, lower for all separate dimensions of the SF-36 and the overall health score of the EuroQol compared to pre-PD patients. However, analyzing the dimensions of the SF-36 together, adjusted for case-mix, pre-HD patients scored significantly lower than pre-PD patients. Mean difference was 6.5 points ( p = 0.04). Conclusion Multivariate adjustment for known case-mix differences at the start of dialysis therapy was not sufficient to adjust for all patient selection effects on QL. Consequently, published QL comparisons between HD and PD in nonrandomized cohort studies should be interpreted with caution. Assessment of QL just before start of dialysis therapy and subsequent adjustment for baseline values may be the only valid alternative for randomized studies.

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The scope of homoeopathy in improving the quality of life in patients with end-stage renal disease: A case series

Journal of Integrated Standardized Homoeopathy ◽

10.25259/jish_24_2020 ◽

2021 ◽

Vol 4 ◽

pp. 4-11 ◽

Cited By ~ 1

Author(s):

Mehvish Haris Dandoti ◽

Anand Ramchandra Kapse

Keyword(s):

Quality Of Life ◽

Renal Failure ◽

Renal Disease ◽

End Stage Renal Disease ◽

Short Form ◽

Case Series ◽

Well Being ◽

Stage Renal Disease ◽

End Stage

Objectives: Lifestyle disorders such as diabetes mellitus, hypertension and cardiovascular diseases eventually affect the kidneys, often causing renal failure. The current gold standard methods for managing renal failure are renal replacement therapy and haemodialysis. Unfortunately, dialysis deteriorates the patient’s quality of life (QOL). Homoeopaths rarely treat cases with such advanced irreversible pathology; the scope of homoeopathy in such cases is, therefore, unclear. We observed the effect of homoeopathy as an adjuvant on the QOL in patients with end-stage renal disease (ESRD). The QOL was assessed using the Marathi version of the Kidney Disease QOL Short Form 1.3 (KDQOL SF version 1.3). Materials and Methods: Three Indian patients with ESRD (two men and one woman, individualized ages 38, 50 and 54 years) consented to have their data published. The cases were managed with constitutional homoeopathic remedies in the 50 millesimal (LM) potency as an adjuvant to their current allopathic medications and were observed for 6 months. They were assessed with the Marathi version of the KDQOL SF 1.3 before and after homoeopathic management along with regular haemodialysis. Results: The patients showed significant improvements in the QOL, especially in the areas of sleep, pain, symptoms and problems, cognitive functioning, emotional well-being and social functioning, as assessed based on the increase in scores in their respective domains. Conclusion: The results of the observations are promising and in concurrence with homoeopathic philosophy; the benefits of constitutional medicines were seen. All three patients showed an improvement in their QOL. However, studies with larger sample size and randomised controlled trial study design are suggested. Homoeopathic constitutional treatment has a significant impact on the QOL in patients with ESRD.

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