scholarly journals Echocardiographic evaluation of complete and incomplete Kawasaki disease in terms of coronary and non coronary cardiac involvement

2017 ◽  
Vol 13 (1) ◽  
pp. 220-224 ◽  
Author(s):  
Uttam Kumar Sarkar ◽  
Anish Chatterjee ◽  
Sumit Periwal ◽  
Suprit Basu ◽  
Indranil Dutta
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Early Diagnosis ◽  
Cardiac Involvement ◽  
Incomplete Kawasaki Disease ◽  
Prompt Treatment ◽  
Echocardiographic Evaluation ◽  
Atypical Kawasaki Disease

Background & Objectives: With increasing incidence of Kawasaki disease and its associated complications, the need of the hour is early diagnosis. Incomplete  Kawasaki is often diagnosed late and is frequently associated with morbidities and mortalities. Our study aims to emphasize the importance of echocardiography in detection of incomplete Kawasaki disease.Materials & Methods: A total of 150 children, clinically diagnosed as Kawasaki disease were evaluated echocardiographically and involvement of coronary artery and associated cardiac involvements were studied.Results: Amongst the incomplete Kawasaki disease patients 76% were from extremes of ages and 19.2% of them had coronary involvement. Myocarditis(38.1%) was the commonest non-coronary findings.Conclusion: Atypical Kawasaki disease is more common in extremes of ages and echocardiography helps in detecting atypical disease at the earliest, thus facilitating prompt treatment and reducing complications.

scholarly journals Combination Thrombolytic and Anti-Platelet Therapies in an Infant with Incomplete Kawasaki Disease and Coronary Aneurysms

2008 ◽  
Vol 13 (4) ◽  
pp. 242-250
Author(s):  
Peter N. Johnson ◽  
Robert J. Kuhn
Keyword(s):  
Septic Shock ◽  
Coronary Artery ◽  
Kawasaki Disease ◽  
Thrombus Formation ◽  
Coronary Aneurysm ◽  
Intravenous Immunoglobulins ◽  
Minimal Change ◽  
Incomplete Kawasaki Disease ◽  
Persistent Fever ◽  
Coronary Aneurysms

A 3-month-old infant was transferred to our facility with persistent fever and concerns for septic shock. A 2-D echocardiogram revealed multiple coronary aneurysms and axillary and coronary artery thrombi, and a diagnosis of incomplete Kawasaki disease (KD) was established. Aggressive therapies including intravenous immunoglobulins, enoxaparin, abciximab, aspirin, and alteplase were used to decrease the size of the coronary aneurysms and inhibit further thrombus formation. After minimal change in the size of coronary aneurysms and in thrombus formation, clopidogrel was added. Approximately 2 weeks after initiation of these therapies, a decrease in the coronary aneurysm size was noted with no signs of thrombus. This case documents successful use of thrombolytic and combination anti-platelet agents (i.e., clopidogrel, abciximab, and aspirin) in an infant with KD and cardiovascular sequelae.

Kawasaki Disease in a Patient With Williams Syndrome

2018 ◽  
Vol 11 (4) ◽  
pp. NP144-NP147
Author(s):  
Aleisha M. Nabower ◽  
Lois J. Starr ◽  
Jonathan Cramer
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Williams Syndrome ◽  
Coronary Arteries ◽  
Incomplete Kawasaki Disease ◽  
Cardiac Anomalies ◽  
Coronary Artery Dilatation ◽  
Coronary Aneurysms

Kawasaki disease can be difficult to diagnose in infants, putting them at higher risk for developing coronary artery dilatation. It can be even more difficult to diagnose in the setting of preexisting cardiac anomalies such as those found in Williams syndrome. We present a case of a three-month-old male with Williams syndrome with rapidly developing giant coronary aneurysms due to Kawasaki disease. This case demonstrates the importance of repeat echocardiography in diagnosing incomplete Kawasaki disease in infants. We speculate that elastin changes, as present in Williams syndrome, may put affected children at higher risk for development of giant coronary arteries should they acquire Kawasaki disease.

scholarly journals Treatment change and coronary artery abnormality in incomplete Kawasaki disease

2020 ◽  
Vol 62 (7) ◽  
pp. 779-784
Author(s):  
Yuichi Nomura ◽  
Mayumi Yashiro ◽  
Kiminori Masuda ◽  
Yoshikazu Nakamura
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Incomplete Kawasaki Disease ◽  
Treatment Change ◽  
Coronary Artery Abnormality

scholarly journals Giant coronary artery aneurysms in a 12-week-old infant with incomplete Kawasaki disease

2018 ◽  
pp. bcr-2018-224479 ◽  
Author(s):  
Lucy Guile ◽  
Simon Parke ◽  
Alison Kelly ◽  
Robert Tulloh
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Incomplete Kawasaki Disease ◽  
Coronary Artery Aneurysms

Abstract 103: Incomplete Kawasaki Disease - Patients With ≦ 5 Days Of Fever Successfully Treated By Antibiotics But Left With Coronary Aneurysms -

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Kenji Suda ◽  
Hiroshi Nishino ◽  
Yoshiyuki Kudo ◽  
Hironaga Yoshimoto ◽  
Shintaro Kishimoto ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Case Series ◽  
Artery Aneurysm ◽  
Ivig Treatment ◽  
Incomplete Kawasaki Disease ◽  
Antithrombotic Treatment ◽  
Coronary Aneurysms ◽  
Appropriate Treatment ◽  
Echocardiographic Examination

Objective: We report four patients with incomplete Kawasaki disease (KD) successfully treated by antibiotics without intravenous immunoglobulin (IVIG) treatment with ≦ 5 days of fever but left with coronary artery lesion. Result: The patients were 2 babies and 2 young children age ranged from 2 months to 2 years old and 9 months. They showed fever and other signs of KD, but did not fulfill diagnostic criteria. The numbers of symptoms compatible with KD were 2 or 3 and included conjunctival injection, oral or lip injection, and eruption. Within 5 days, they became afebrile by antibiotics without IVIG treatment. However, they were noted to have coronary artery aneurysm (CAA) on day from 7 to 33 of illness. All patients had been placed on antithrombotic treatment including aspirin or aspirin plus warfarin and, fortunately, showed regression of CAA within 2 years. Conclusions: This case series indicates that there are patients with incomplete KD successfully treated by antibiotics without IVIG but left with CAA. These cases must be underdiagnosed if intentional echocardiographic examination are scheduled and might be left without appropriate treatment, antithrombotic treatment. Further collection of data of these patients is indispensable.

Atypical Kawasaki Disease with Coronary Artery Involvement

1998 ◽  
Vol 18 (4) ◽  
pp. 345-346
Author(s):  
Sulaiman Al-Mayouf ◽  
Sami Al-Hajjar ◽  
Sultan Bahabri
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Coronary Artery Involvement ◽  
Atypical Kawasaki Disease
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