scholarly journals Echocardiographic abnormalities in non-moderate drinking of alcohol for prolonged duration

1970 ◽  
Vol 6 (1) ◽  
pp. 18-28
Author(s):  
MP Gautam ◽  
U Ghimire Gautam ◽  
S Dwivedi ◽  
S Rijal
Keyword(s):  
Ejection Fraction ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Systolic Dysfunction ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Moderate Drinking ◽  
Ventricular Mass Index ◽  
Total Lifetime ◽  
Ventricular Mass

Background: Alcohol drinking is cardio-protective; however its beneficial and harmful effects depend on the amount consumed. This work is designed to assess the impact of prolonged non-moderate drinking in left ventricular mass index and left ventricular ejection fraction and the correlation of their severity with total lifetime intake amount. Materials and methods: Fifty non-moderate drinkers (>25 g/day) for last 10 years and 50 non-drinker-volunteers were selected. Detail echocardiographic assessment was done and findings were compared and severity was correlated with lifetime amount. Results: Mean daily intake, duration and lifetime intake amount of alcohol were 64.1 g, 21.9 years and 501.9 Kg respectively. The mean ejection fraction and left ventricular mass index were 47.2% and 105.3 g/m2. There was significant difference when compared with controls. Eighty-two percent drinking subjects had abnormal echo, most common were regurgitations (52%), diastolic dysfunction (46%), raised ventricular mass (44%), systolic dysfunction (40%), and dilated left atrium and ventricle (38%). Thirty-four percent of subjects had echo features consistent with dilated cardiomyopathy. Palpitation and dyspnea in combination were the only symptoms associated with severity of echo changes. There was strong negative correlation of lifetime intake amount with ejection fraction (r = -0.91, p<0.001); however its relationship with ventricular mass index was not statistically significant (r = 0.23, p>0.05). Conclusions: Prolonged non-moderate drinking causes significant echocardiographic abnormalities mainly systolic dysfunction and increased left ventricular mass index. The total lifetime and daily amount of alcohol are well correlated with systolic dysfunction; however their relationships with the left ventricular mass index were non-conclusive. Key words: Alcohol; left ventricular mass; cardiomyopathy DOI: 10.3126/jcmsn.v6i1.3598 Journal of College of Medical Sciences-Nepal, 2010, Vol. 6, No. 1, 18-28

Effect of Therapy on Left Ventricular Function in Hypertension

1980 ◽  
Vol 59 (s6) ◽  
pp. 435s-439s ◽  
Author(s):  
I. Khatri ◽  
J. Gottdiener ◽  
A. Notargiacomo ◽  
E. Freis
Keyword(s):  
Blood Pressure ◽  
Ejection Fraction ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Blood Pressure Reduction ◽  
Control Level ◽  
Left Ventricular ◽  
Temporary Increase ◽  
Ventricular Mass Index ◽  
Ventricular Mass

1. Twelve untreated hypertensive patients whose blood pressure was 171.8 ± 5.5 mmHg systolic and 119.7 ± 3.4 mmHg diastolic (mean ± sem) were treated aggressively with diuretics plus other antihypertensive agents. Echocardiograms were performed before, and 2 weeks, 3 months and 6 months after therapy. Blood pressures were lowered to an average of 142/98 mmHg over the 6 month period. 2. Mean velocity of circumferential fibre shortening rose from 1.1 ± 0.09 to 1.3 ± 0.06 diameters/s at 2 weeks and remained elevated at the end of 3 months (1.3 ± 0.03 diameters/s) (P&lt;0.025), but returned to the control level in 6 months. Similarly, ejection fraction increased significantly during the same period from a control value of 65.1 ± 4.4 to 73.4 ± 1.8% (P&lt;0.025) and persisted in this range at 3 months. At 6 months the ejection fraction had returned to pretreatment levels. There were significant reductions in left ventricular end-systolic and end-diastolic dimensions. Left ventricular mass index decreased from 182.3 ± 18.3 to 163.8 ± 12.4 g/m2 after 6 months of therapy. 3. These results indicate that in the early stages of blood pressure reduction there is a temporary increase in ejection phase indices, probably related to afterload reduction. The reduction in the left ventricular mass index suggests that increased cardiac muscle mass due to elevated blood pressure may be partially reversible after long-term reduction in blood pressure.

scholarly journals Complete correction of anemia with Recormon® (Wrythropoietin β) in patients on chronic hemodialysis

2015 ◽  
Vol 68 (9-10) ◽  
pp. 324-330 ◽  
Author(s):  
Nada Dimkovic ◽  
Igor Mitic ◽  
Branislav Andric ◽  
Branislav Lilic-Havidza ◽  
Rosa Jelacic ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Left Ventricular Mass ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Mass Index ◽  
Hemodialysis Patients ◽  
Left Ventricular ◽  
Hemoglobin Level ◽  
Left Ventricular Ejection ◽  
Ventricular Mass Index ◽  
Ventricular Mass

Introduction. Suboptimal correction of anemia is associated with increased prevalence of cardiovascular diseases and increased morbidity and mortality of pre-dialysis and dialysis patients. The aim of the study was to compare the effect of optimal vs. suboptimal correction of anemia in hemodialysis patients with left ventricular hypertrophy. Material and Methods. The study included 50 patients, 32 males and 18 females, their mean age being 49.4?11.8 years, from five hemodialysis centers (Clinical Hospital Center Zvezdara, Beograd, Clinical Center Novi Sad, hospitals in Krusevac, Pirot and Zrenjanin). The patients had suboptimal hemoglobin level in spite of therapy (7.8?3.8 g/dl). In addition, the most important inclusion criteria was the left ventricular mass index above 160 g/m2 and the primary efficacy parameter was a decrease in the left ventricular mass index during 12 month study period. Results. During the study, the number of patients who reached their hemoglobin >12 g/dl increased and the target hemoglobin (12-13 g/dl) was achieved in 24 (52%) of patients at the end of the study. At the same time, the left ventricular mass index significantly decreased as compared with the initial values (p=0.014). The left ventricular mass index was not significantly decreased in the patients who did not achieve the target hemoglobin level (207?65 vs. 217?38 g, p=ns) as compared with the patients who achieved the target hemoglobin (179?32 g/ m2 vs. 197?38 g/m2, p=0.007). The left ventricular ejection fraction did not change significantly during the study period. Conclusion. Anemia correction with erythropoietin ? resulted in the significantly corrected left ventricular hypertrophy in hemodialysis patients who had had a suboptimal hemoglobin level. Our results have shown that correction of left ventricular hypertrophy is possible with hemoglobin value of 12 g/dl at least.

The association of ankle brachial index with left ventricular hypertrophy and left ventricular mass index: the Dong-gu study

VASA ◽  
2013 ◽  
Vol 42 (4) ◽  
pp. 284-291 ◽  
Author(s):  
Seong-Woo Choi ◽  
Hye-Yeon Kim ◽  
Hye-Ran Ahn ◽  
Young-Hoon Lee ◽  
Sun-Seog Kweon ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Left Ventricular Mass ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Mass Index ◽  
Ankle Brachial Index ◽  
Intima Media Thickness ◽  
Left Ventricular ◽  
Baseline Survey ◽  
Ventricular Mass Index ◽  
Ventricular Mass

Background: To investigate the association between ankle-brachial index (ABI), left ventricular hypertrophy (LVH) and left ventricular mass index (LVMI) in a general population. Patients and methods: The study population consisted of 8,246 people aged 50 years and older who participated in the baseline survey of the Dong-gu Study conducted in Korea between 2007 and 2010. Trained research technicians measured LV mass using mode M ultrasound echocardiography and ABI using an oscillometric method. Results: After adjustment for risk factors and common carotid artery intima-media thickness (CCA-IMT) and the number of plaques, higher ABIs (1.10 1.19, 1.20 - 1.29, and ≥ 1.30) were significantly and linearly associated with high LVMI (1.10 - 1.19 ABI: β, 3.33; 95 % CI, 1.72 - 4.93; 1.20 - 1.29 ABI: β, 6.51; 95 % CI, 4.02 - 9.00; ≥ 1.30 ABI: β, 14.83; 95 % CI, 6.18 - 23.48). An ABI of 1.10 - 1.19 and 1.20 - 1.29 ABI was significantly associated with LVH (1.10 - 1.19 ABI: OR, 1.35; 95 % CI, 1.19 - 1.53; 1.20 - 1.29 ABI: OR, 1.59; 95 % CI, 1.31 - 1.92) and ABI ≥ 1.30 was marginally associated with LVH (OR, 1.73; 95 % CI, 0.93 - 3.22, p = 0.078). Conclusions: After adjustment for other cardiovascular variables and CCA-IMT and the number of plaques, higher ABIs are associated with LVH and LVMI in Koreans aged 50 years and older.

Association between left ventricular mass index and cardiac function in pediatric dialysis patients

2011 ◽  
Vol 27 (5) ◽  
pp. 835-841 ◽  
Author(s):  
Pirouz Shamszad ◽  
Timothy C. Slesnick ◽  
E. O’Brian Smith ◽  
Michael D. Taylor ◽  
Daniel I. Feig
Keyword(s):  
Cardiac Function ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
Dialysis Patients ◽  
Pediatric Dialysis ◽  
Ventricular Mass Index ◽  
Ventricular Mass ◽  
Pediatric Dialysis Patients
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