scholarly journals Utility of fine needle aspiration cytology in head and neck lesions and its correlation with histopathology- a study in tertiary care hospital

2020 ◽  
Vol 10 (2) ◽  
pp. 1733-1741
Author(s):  
Sushma Thapa ◽  
Arnab Ghosh ◽  
Dilasma Ghartmagar ◽  
Sudeep Regmi ◽  
OP Talwar

Background: Fine Needle Aspiration Cytology has rapidly gained acceptance due to the easy accessibility of target sites and minimally invasive nature. It is a very simple, quick, cost-effective method of sampling alternative to the time consuming complicated and invasive excision biopsy. The study aimed to access the utility of fine needle aspiration cytology in the diagnosis of various head and neck lesions and also to establish the diagnostic accuracy between the cytological and histopathological diagnosis. Materials and Methods: A retrospective observational study of 380 cases of FNACs on head and neck swellings performed in various age groups in the Department of Pathology of a tertiary care hospital from January 2018 to December 2019.  Results: Out of 380 patients, the maximum number of cases were seen in the thyroid (40.8%), followed by lymph nodes (39.5%), skin, soft tissue, miscellaneous (10.8%) and salivary glands (8.9%). Benign and non-neoplastic cases outnumbered (88.1%) the malignant (10.8%) cases. Histopathological follow-up was available in 28 (7.4%) cases among which 25 (89.3%) cases were consistent with the cytodiagnosis. The sensitivity, specificity, and diagnostic accuracy were evaluated to be 80%, 94.4%, and 89.3% respectively. Conclusions: The majority of the cases of head and neck swellings were seen in the thyroid followed by lymph nodes, skin, soft tissue, miscellaneous, and salivary glands. In thyroid, colloid goiter and papillary carcinoma were the commonest benign and malignant lesions respectively. In the lymph node, reactive lymphadenitis, and metastatic squamous cell carcinoma were the commonest benign and malignant lesions respectively.

2021 ◽  
Vol Volume 9 (upjohns/volume9/Issue2) ◽  
pp. 15-21
Author(s):  
Sachin Jain

ABSTRACT Aims: This prospective study was carried out to compare findings of the four procedures namely FNAC (fine-needle aspiration cytology), USG (ultrasonography), US-FNAC (Ultrasound-guided fine-needle aspiration cytology), and HPE (histopathological examination). MATERIAL AND METHODS Total 80 cases of different neck swellings were selected from ENT OPD at tertiary care hospital Prayagraj Uttar Pradesh. All cases underwent the preoperative procedure of FNAC,USG, US-FNAC and postoperative HPE for diagnosing the neck swelling. The results of FNAC, USG, US-FNAC w e r e c o m p a r e d a n d c o r r e l a t e d w i t h histopathology findings and conclusions drawn after statistical analysis. RESULTS More than half (56.25%) of neck swellings were of thyroid swellings. It was observed that sensitivity, specificity, PPV, NPV, accuracy of FNAC of all neck swellings were 85.71%, 91.78% ,50%, 98.53% ,91.25% respectively. Sensitivity ,specificity, PPV ,NPV , accuracy of all neck swellings of USG were 71.43%, 98.63%, 83.33% , 97.26% 96.25 respectively. Sensitivity ,specificity, PPV ,NPV , accuracy of all neck swellings of US-FNAC were 85.71% ,97.26% ,75% , 98.61%, 96.25 respectively. CONCLUSION The combined use of USG and FNAC give more accuracy for proper diagnosis of neck swelling than FNAC alone. The most accurate diagnosis of


2020 ◽  
Vol 7 (10) ◽  
pp. 3333
Author(s):  
Meena Asokan ◽  
Shanavas Cholakkal ◽  
Bibilash Babu Susheela ◽  
Hima Abdurahiman

Background: Multinodular goiter (MNG) occurs due to repeated hyperstimulation of thyroid gland due to iodine deficiency, goitrogens, antithyroid drugs and genetic defects. MNG can have different complications which include treacheal compression, retrosternal extension, malignancy and secondary thyrotoxicosis. The aim of the work was to study the clinical features and histopathology of MN in patients admitted for thyroidectomy in surgical wards of a tertiary care hospital in north Kerala.Methods: A prospective hospital based observational study in the patients in surgical wards of a tertiary care hospital in north Kerala from April 2011 to March 2012. The clinical data of patients who are subjected to thyroidectomy for MNG (clinical and fine needle aspiration cytology diagnosis) were included in this study. Patients undergoing completion thyroidectomy for recurrence or malignancy were excluded from this study.Results: MNG is more common in females. Female to male ratio 24:1 Majority are in the age group of 30-50 years (64%) with a mean age of 41 years. 38% (38 cases) had pressure symptoms in the form of dysphagia or dyspnea. Secondary thyrotoxicosis seen in 17% (17 cases). Fine needle aspiration cytology (FNAC) is not an error-proof investigation in MNG. 14 % of our patients had malignancy inspite of being reported as benign in FNAC. Among the malignancies papillary carcinoma thyroid was found to be most common accounting for 12% of cases (12/100) followed by follicular carcinoma.Conclusions: FNAC is not an error proof investigation in MNG. Incidental thyroid cancer in MNG is about 14 % with papillary carcinoma thyroid being the commonest.


Author(s):  
Musfika Tabassum ◽  
Monoj Kumar Deka ◽  
Nitu Mani Khakhlari

Background: Fine Needle Aspiration Cytology (FNAC) of the salivary gland is one of the most challenging in the field of cytopathology due to the wide spectrum of lesions. There is significant cytomorphologic diversity and overlap between many benign and malignant salivary gland tumours. Though FNAC is quite an effective tool for the diagnosis of salivary gland lesions, it has always been under scrutiny and histopathology continues to be the final method to establish a diagnosis.Methods: A total of 80 patients who presented with clinical diagnosis of salivary gland mass at the Department of Pathology, SMCH, Assam from August 2017 to August 2019 were included in the study. FNAC was performed in all the cases and the cytological findings were correlated with that of the histopathological findings (wherever possible).Results: The median age group of patients was in the range of 30-40 years (30%). 60 patients underwent surgical procedure and hence histopathological correlation could be done in these patients. Among the various diagnosis in FNAC, benign tumours constitute the majority with 36 cases (60%). The most commonly involved benign tumour was pleomorphic adenoma (27 cases). The overall sensitivity, specificity & diagnostic accuracy of FNAC were found to be 87.3%, 93.9% and 93.33% respectively.Conclusions: FNAC is a safe, reliable, time saving, cost-effective, convenient and accurate method and should be considered as one of the pivotal investigations in the evaluation of salivary gland lesions.


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