scholarly journals Anthropogenic organic compounds in source water of select community water systems in the United States, 2002-10

2014 ◽  
Author(s):  
Joshua F. Valder ◽  
Gregory C. Delzer ◽  
James A. Kingsbury ◽  
Jessica A. Hopple ◽  
Curtis V. Price ◽  
...  
Keyword(s):  
United States ◽  
Organic Compounds ◽  
The United States ◽  
Water Systems ◽  
Source Water ◽  
Community Water Systems ◽  
Community Water

Associations of Community Water Lead Concentrations with Hemoglobin Concentrations and Erythropoietin-Stimulating Agent Use among Patients with Advanced CKD

2021 ◽  
pp. ASN.2020091281
Author(s):  
John Danziger ◽  
Kenneth J. Mukamal ◽  
Eric Weinhandl
Keyword(s):  
United States ◽  
Drinking Water ◽  
Kidney Disease ◽  
The United States ◽  
Water Systems ◽  
Adverse Outcomes ◽  
Content Type ◽  
Community Water Systems ◽  
Community Water ◽  
Lead Levels

BackgroundAlthough patients with kidney disease may be particularly susceptible to the adverse health effects associated with lead exposure, whether levels of lead found commonly in drinking water are associated with adverse outcomes in patients with ESKD is not known.MethodsTo investigate associations of lead in community water systems with hemoglobin concentrations and erythropoietin stimulating agent (ESA) use among incident patients with ESKD, we merged data from the Environmental Protection Agency (EPA) Safe Drinking Water Information System (documenting average 90th percentile lead concentrations in community water systems during 5 years before dialysis initiation, according to city of residence) with patient-level data from the United States Renal Data System.ResultsAmong 597,968 patients initiating dialysis in the United States in 2005 through 2017, those in cities with detectable lead levels in community water had significantly lower pre-ESKD hemoglobin concentrations and more ESA use per 0.01 mg/L increase in 90th percentile water lead. Findings were similar for the 208,912 patients with data from the first month of ESKD therapy, with lower hemoglobin and higher ESA use per 0.01 mg/L higher lead concentration. These associations were observed at lead levels below the EPA threshold (0.015 mg/L) that mandates regulatory action. We also observed environmental inequities, finding significantly higher water lead levels and slower declines over time among Black versus White patients.ConclusionsThis first nationwide analysis linking EPA water supply records to patient data shows that even low levels of lead that are commonly encountered in community water systems throughout the United States are associated with lower hemoglobin levels and higher ESA use among patients with advanced kidney disease.

scholarly journals Uranium and metal concentrations in community water systems across the United States, 2006-2011

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Filippo Ravalli ◽  
Yuanzhi Yu ◽  
Benjamin C. Bostick ◽  
Steven N. Chillrud ◽  
Kathrin Schilling ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Water Systems ◽  
Metal Concentrations ◽  
Community Water Systems ◽  
Community Water
Sign in / Sign up

Export Citation Format

Share Document