Solitary fibrous tumor of the pleura: A rare mesenchymal tumor presented with hypoglycemia

Solitary fibrous tumor (SFT) is a relatively rare primary tumor of the pleura, originating from the mesenchymal cells. The tumor has a non-specific clinical, laboratory, and radiological features. Patients may be asymptomatic or have non-specific clinical features including chest pain, dyspnea, cough, and paraneoplastic symptoms. Complete surgical resection is indicated in all cases to avoid recurrence of the tumor. We described a 49-yearold woman who presented with unexplained right chest pain and repeated attacks of hypoglycemia, associated with pleural SFT. Keywords: Pleura; thoracic oncology; solitary fibrous tumor; paraneoplastic hypoglycemia; Doege-Potter syndrome

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Two case reports of rare diseases occurring in rare parts: Splenic vein solitary fibrous tumor and Liver solitary fibrous tumor

10.21203/rs.3.rs-32710/v1 ◽

2020 ◽

Author(s):

Wenjing Wang ◽

Banghe Bao ◽

Anbin Hu ◽

Xiaofeng Zhu ◽

Qing Chen

Keyword(s):

Liver Transplantation ◽

Surgical Resection ◽

Orthotopic Liver Transplantation ◽

Solitary Fibrous Tumor ◽

Primary Tumor ◽

Splenic Vein ◽

Tumor Site ◽

Primary Tumor Site ◽

Fibrous Tumor

Abstract Background Solitary fibrous tumor (SFT) is a rare soft tissue tumor originating from mesenchyme. Two cases of SFT we report right now occurred in the splenic vein and liver respectively, this primary splenic vein SFT may be the first report case, and also the first report of liver recurrence SFT cured by orthotopic liver transplantation (OLT). Case presentation One case was a 37-year-old female patient whose primary tumor site was located in the splenic vein, which resulted in splenomegaly and hypersplenism; its recurrence again and again after surgical resection and eventually transferred to the liver, during 10 years of follow-up, 4 operations were performed, and he is in a good condition right now. The second case was a 54-year-old male patient whose primary tumor site was located in the liver, spleen and left side of the chest wall; however, he had no uncomfortable symptoms. Surgeons performed two operations to remove these tumors, totally. 6 years later, SFT recurrence in the liver, and given that the tumor was so large that it could not be completely surgical resected, we chose orthotopic liver transplantation (OLT), and no tumor recurrence during 12-month follow-up. Conclusion The reports of these two cases of SFT are very rare, especially the splenic vein SFT, which expand the understanding of SFT. The main treatment of SFT is still surgical resection, right now, and liver transplantation may be a new option treatment for the huge liver SFT.

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Diagnosis, treatment, and rehabilitation of a patient with inflammatory pseudotumor

European Journal of Dentistry ◽

10.4103/ejd.ejd_333_17 ◽

2018 ◽

Vol 12 (03) ◽

pp. 454-458

Author(s):

Flávio Tendolo Fayad ◽

Matheus Cavalcante Tomaz Bezerra ◽

Marina Rolo Pinheiro da Rosa ◽

Tiago Novaes Pinheiro

Keyword(s):

Surgical Resection ◽

Clinical Features ◽

Inflammatory Pseudotumor ◽

Multidisciplinary Treatment ◽

Unknown Etiology ◽

Functional Rehabilitation ◽

Multiple Biopsies ◽

Complete Surgical Resection ◽

Inflammatory Pseudotumors ◽

Maxillary Region

ABSTRACTInflammatory pseudotumors are a group of lesions of unknown etiology that mimic clinically and radiographically neoplasms. In the maxilla, inflammatory pseudotumors are presented with bone alterations of erosion, remodeling, and sclerosis. The diagnosis is of exclusion, where multiple biopsies are required. The present study aims to report the case of a male patient who presented with increased volume in the left maxillary region, with diagnosis after total left maxillectomy being inflammatory pseudotumor. The patient did not present recurrences with 3 years of preservation and underwent by multidisciplinary treatment with esthetic and functional rehabilitation with the preparation of a bucomaxilo prosthesis. Despite presenting some suggestive clinical features, the inflammatory pseudotumor has a difficult and of exclusion diagnosis, where multiple biopsies are required. They are lesions that simulate clinically and radiographically neoplasms. If it is surgically accessible, the treatment of choice is complete surgical resection.

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Prognostic factors influencing survival in small bowel neuroendocrine tumors with liver metastasis.

Journal of Clinical Oncology ◽

10.1200/jco.2017.35.15_suppl.e15688 ◽

2017 ◽

Vol 35 (15_suppl) ◽

pp. e15688-e15688

Author(s):

Nicholas Manguso ◽

Attiya Harit ◽

Nicholas N. Nissen ◽

James Mirocha ◽

Andrew Eugene Hendifar ◽

...

Keyword(s):

Liver Metastasis ◽

Small Bowel ◽

Surgical Resection ◽

Primary Tumor ◽

Cox Regression ◽

Tumor Grade ◽

Median Number ◽

Risk Of Death ◽

Increased Risk ◽

Complete Surgical Resection

e15688 Background: Management of liver metastasis in patients with small bowel neuroendocrine tumors (SBNET) remains unclear. Complete surgical resection improves long term survival however factors that influence overall prognosis are not clear. Methods: Database review identified 301 patients diagnosed with SBNET from 1990 to 2013. Only patients with known liver metastasis who underwent resection of the primary tumor were included. Outcomes among patients who underwent complete surgical resection, incomplete debulking of liver metastasis, and resection of the primary tumor alone were compared. The Kaplan-Meier method was used for survival estimates and Cox regression was used to identify predictors of death. Results: 111 patients met study criteria. Median age was 59 years (range 16-80); 49% were male. The terminal ileum (47/111, 42%) was the most common primary tumor location. The median number of liver lesions was 8.5 (range 1-31) and median lesions resected was 1 (range 0-31). In addition to resection of the primary tumor, 36 patients (32%) had no liver resection (NR), 41 (36.9%) had complete resection of liver disease (R0) and 34 (30%) had incomplete resection of liver metastasis (R1). 58 patients (36%) had one or more wedge resections, 12 (10.8%) underwent segmentectomy and 5 (4.5%) had a lobectomy. 33 (29.7%) patients underwent post-operative chemoembolization, 25 (22.5%) had radioembolization and 23 (20.7%) had radiofrequency ablation. The R1 group differed from the R0 group in median size of primary tumor (2.5 cm R1 vs 1.6 cm R0, p = 0.05) and median number of positive lymph nodes (5.0 R1 vs 3.0 R0, p = 0.05). The 5-year OS was 80.9%, 81.1% and 100% for NR, R1 and R0 groups respectively (p = 0.01). 10-year OS did not differ between groups (72.8% NR vs 81.1% R1vs 82.5% NR, p = 0.31). Cox regression showed post-operative administration of chemotherapy (HR = 3.68, p < 0.01) and higher tumor grade (HR = 18.4, p = 0.02) increased risk of death. Conclusions: In patients with SBNET with liver metastasis, higher tumor grade and post-operative chemotherapy increased risk of death. However, resection of the primary tumor along with liver metastasis improves the 5-year OS with complete cytoreduction providing the most benefit.

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Solitary fibrous tumor of the pleura: 3 case reports

Revista da Associação Médica Brasileira ◽

10.1590/1806-9282.61.03.207 ◽

2015 ◽

Vol 61 (3) ◽

pp. 207-208 ◽

Cited By ~ 1

Author(s):

Elias Amorim

Keyword(s):

Solitary Fibrous Tumor ◽

Case Reports ◽

Benign Lesion ◽

Complete Resection ◽

The Other ◽

Posterolateral Thoracotomy ◽

Pertinent Literature ◽

Complete Surgical Resection ◽

Fibrous Tumor

Summary Introduction: solitary fibrous tumor of the pleura (SFTP) is a rare tumor arising from mesenchymatous cells in submesothelial pleural tissue which, unlike mesothelioma, is not related to asbestos or smoking. Methods: report of four patients who underwent surgical treatment for giant SFTP and review of the pertinent literature. Results: of the four patients operated, two presented symptoms including cough, chest pain and feeling of compression, whereas the other two subjects were asymptomatic. All patients underwent complete surgical resection by wide posterolateral thoracotomy, and surgical specimens removed with minimum bleeding. None of the cases required complementary lobectomy or segmentectomy. All tumors were histologically benign. Conclusion: complete resection of the lesion is the treatment of choice in all SFTP cases. Prognosis of the benign lesion is excellent, although close follow-up is necessary. In the rarer, more aggressive forms, treatment may be complemented by adjunctive chemotherapy or radiotherapy, the benefits of which have yet to be confirmed.

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Giant solitary fibrous tumor of the pelvis successfully treated with preoperative embolization and surgical resection: a case report

World Journal of Surgical Oncology ◽

10.1186/s12957-015-0578-6 ◽

2015 ◽

Vol 13 (1) ◽

Cited By ~ 13

Author(s):

Yuichiro Yokoyama ◽

Keisuke Hata ◽

Takamitsu Kanazawa ◽

Hironori Yamaguchi ◽

Soichiro Ishihara ◽

...

Keyword(s):

Case Report ◽

Surgical Resection ◽

Solitary Fibrous Tumor ◽

Preoperative Embolization ◽

Fibrous Tumor

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A rare cause of chest pain: pleuropulmonary solitary fibrous tumor

Current Thoracic Surgery ◽

10.26663/cts.2019.00126 ◽

2019 ◽

Vol 4 (3) ◽

pp. 136

Author(s):

Raúl Gonzalez Luna ◽

Gerardo Rea Mendoza ◽

Christian Ramirez Sanchez

Keyword(s):

Chest Pain ◽

Solitary Fibrous Tumor ◽

Fibrous Tumor

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Solitary Fibrous Tumor: Case Report of Intrapulmonary Location

Case Reports in Oncological Medicine ◽

10.1155/2018/5745471 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4

Author(s):

Adil Arsalane ◽

Abdelfetah Zidane ◽

Hicham Fenane ◽

Amine Azami ◽

Ismail Essadi ◽

...

Keyword(s):

Case Report ◽

Surgical Resection ◽

Solitary Fibrous Tumor ◽

Visceral Pleura ◽

Clinical Imaging ◽

Histological Features ◽

Solitary Fibrous Tumors ◽

Fibrous Tumor ◽

Malignant Behavior

Solitary fibrous tumors are relatively rare neoplasms that commonly occur in the pleura, especially visceral pleura. However, an intrapulmonary site of this kind of tumors is even rarer. These tumors can be characterized by a heterogeneous evolution and have a benign or malignant behavior. Wide surgical resection is essential to cure the patient and to avoid recurrence. We present here the clinical, imaging, and histological features of a case with solitary fibrous tumor growing inside the lung.

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