Treatment of Chronic Central Serous Chorioretinopathy Via Electromagnetic Stimulation and Platelet- Rich Plasma

2020 ◽  
Author(s):  
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Platelet Rich Plasma ◽  
Chronic Central Serous Chorioretinopathy ◽  
Electromagnetic Stimulation

Treatment of resistant chronic central serous chorioretinopathy via platelet-rich plasma with electromagnetic stimulation

2020 ◽  
Author(s):  
Umut Arslan ◽  
Emin Özmert
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Platelet Rich Plasma ◽  
Chronic Central Serous Chorioretinopathy ◽  
Electromagnetic Stimulation ◽  
Micropulse Laser ◽  
Corrected Visual Acuity ◽  
Before And After ◽  
Subtenon Injection ◽  
The Mean ◽  
Best Corrected Visual Acuity

Background: To evaluate whether subtenon injection of platelet-rich plasma (PRP) with retinal electromagnetic stimulation (rEMS) is effective in therapy-resistant chronic central serous chorioretinopathy (CSCR). Design: Prospective, sequential. Materials & methods: The study included 22 eyes with resistant chronic CSCR. Cases receiving micropulse laser or additional photodynamic therapy, subtenon PRP, and subtenon PRP + rEMS were classified as times 1, 2 and 3, respectively. Results: At time 3, the mean best-corrected visual acuity was 85.7 and 97.0 letters before and after the procedures, respectively (p = 0.01). Submacular thickness improved by 17, 27 and 51% at times 1, 2 and 3 respectively. Conclusion: For treating resistant CSCR, subtenon PRP + rEMS should be considered as an effective and safe option. Trial Registration: ClinicalTrials.gov ID: NCT04224831

scholarly journals Macular pigment optical density in central serous chorioretinopathy

2021 ◽  
Vol 13 ◽  
pp. 251584142199719
Author(s):  
Burcu Polat Gultekin ◽  
Esra Sahli
Keyword(s):  
Confidence Interval ◽  
Optical Density ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Macular Pigment ◽  
Central Retinal Thickness ◽  
Macular Pigment Optical Density ◽  
Chronic Central Serous Chorioretinopathy ◽  
Acute Central Serous Chorioretinopathy

Purpose: The aim of our study was to evaluate the macular pigment optical density in patients with acute and chronic central serous chorioretinopathy and to describe the association between central retinal thickness and choroidal thickness with the macular pigment optical density. Materials and Methods: Eyes with acute central serous chorioretinopathy and chronic central serous chorioretinopathy (patients, who were diagnosed as having disease activity for 6 months) were included in this study. Macular pigment was measured using the heterochromatic flicker technique of the MPS II device for both eyes in patients with acute and chronic central serous chorioretinopathy and in control subjects. Results: Twenty-seven eyes with acute central serous chorioretinopathy, 23 eyes with chronic central serous chorioretinopathy, and 25 control eyes were enrolled. The mean macular pigment optical density in chronic central serous chorioretinopathy (0.480 ± 0.16 density unit (95% confidence interval: 0.390–0.570) was found to be significantly lower than in the control eyes (0.571 ± 0.128 density unit) (95% confidence interval: 0.480–0.670) ( p = 0.007). In correlation analysis, no significant association was detected between the central retinal thickness, choroidal thickness, and macular pigment optical density values in central serous chorioretinopathy group ( p = 0.31, p = 0.71). Conclusion: Macular pigment optical density levels were significantly lower in chronic central serous chorioretinopathy patients than in controls, possibly due to degeneration of the neurosensorial retina, as a result of the long-term persistence of subretinal fluid. There was not a significant correlation between choroidal thickness and macular pigment optical density levels in central serous chorioretinopathy group.

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