Bipolar Disorders: Antipsychotic Drug Therapy of Aripiprazole an Open Label Study

Patients with bipolar disorder are exceptionally challenging to manage because of the dynamic, chronic, and fluctuating nature of their disease. Typically, the symptoms of bipolar disorder first appear in adolescence or early adulthood, and are repeated over the patient's lifetime, expressed as unpredictable recurrences of hypomanic/manic or depressive episodes. The lifetime prevalence of bipolar disorder in adults is reported to be approximately 4%, and its management was estimated to cost the US healthcare system in 2009 $150 billion in combined direct and indirect costs.

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Bipolar Disorders: Antipsychotic Drug Therapy of Aripiprazole an Open Label Study

Neuroscience and Neurological Surgery ◽

10.31579/2578-8868/036 ◽

2018 ◽

Vol 3 (1) ◽

pp. 01-02

Author(s):

Amycus Alecto

Keyword(s):

Bipolar Disorder ◽

Early Adulthood ◽

Indirect Costs ◽

Bipolar Disorders ◽

Open Label ◽

Open Label Study ◽

Label Study ◽

Direct And Indirect Costs ◽

The Us ◽

Depressive Episodes

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Efficacy and tolerability of quetiapine in the treatment of bipolar disorder: preliminary evidence from a 12-month open-label study

Journal of Affective Disorders ◽

10.1016/s0165-0327(02)00075-7 ◽

2003 ◽

Vol 76 (1-3) ◽

pp. 267-271 ◽

Cited By ~ 31

Author(s):

A Altamura

Keyword(s):

Bipolar Disorder ◽

Preliminary Evidence ◽

Open Label ◽

Open Label Study ◽

Label Study

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A three-year, open label study of adjunctive memantine in treatment-resistant bipolar disorder

International Clinical Psychopharmacology ◽

10.1097/01.yic.0000423268.17563.2b ◽

2012 ◽

Vol 28 ◽

pp. e22

Author(s):

G. Serra

Keyword(s):

Bipolar Disorder ◽

Treatment Resistant ◽

Open Label ◽

Open Label Study ◽

Label Study

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Clinical experience with gabapentin in patients with bipolar disorder: Results of an open label study

European Psychiatry ◽

10.1016/s0924-9338(99)80404-0 ◽

1998 ◽

Vol 13 (S4) ◽

pp. 244s-244s

Author(s):

P.L. Cabras ◽

J. Hardoy ◽

C. Hardoy

Keyword(s):

Bipolar Disorder ◽

Clinical Experience ◽

Open Label ◽

Open Label Study ◽

Label Study

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In de Quervain’s with a separate EPB compartment, ultrasound-guided steroid injection is more effective than a clinical injection technique: a prospective open-label study

Journal of Hand Surgery (European Volume) ◽

10.1177/1753193411427829 ◽

2011 ◽

Vol 37 (6) ◽

pp. 523-527 ◽

Cited By ~ 34

Author(s):

K. Kume ◽

K. Amano ◽

S. Yamada ◽

K. Amano ◽

N. Kuwaba ◽

...

Keyword(s):

Analogue Scale ◽

Steroid Injection ◽

Injection Technique ◽

Ultrasound Guided ◽

Open Label ◽

Open Label Study ◽

Label Study ◽

De Quervain’S Disease ◽

The Us ◽

Manual Group

We compared ultrasonography (US)-guided injection, targeting the extensor pollicis brevis (EPB) in de Quervain’s disease (dQD) with septation, to clinical injection. Forty-four wrists were randomly allocated to US-guided or manual (non-US-guided) injection. At 4 weeks, pain was significantly reduced in both groups. Pain on the 100 mm visual analogue scale (VAS) for the US group was 80.3 (SD 19.6) mm at baseline and 25.6 (SD 15.1) mm at 4 weeks after injection ( p = 0.004). Values for the manual group were 78.0 (SD 18.5) mm at baseline and 58.2 (SD 21.9) mm at 4 weeks after injection ( p = 0.04). Pain on the VAS showed a more significant decrease in the US-guided than in the manual injection group ( p = 0.0007) from baseline to 4 weeks after injection. The results of this study suggest US-guided injection targeting the EPB in dQD patients with septation is more effective than manual injection.

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