Neuroblastoma-like schwannoma of lumbar spinal nerve root

2010 ◽  
Vol 13 (1) ◽  
pp. 82-86 ◽  
Author(s):  
Giriraj K. Sharma ◽  
Jennifer M. Eschbacher ◽  
Timothy D. Uschold ◽  
Nicholas Theodore

Neuroblastoma-like schwannoma is a rare nerve sheath tumor with histological features resembling a neuroblastoma. A comprehensive literature review identified only 10 previous case reports of this condition. The authors present the first reported case of a neuroblastoma-like schwannoma at a spinal nerve root. The patient, a 61-year-old woman, presented with severe pain in the right lower extremity that failed to resolve after conservative management. Magnetic resonance imaging revealed an intradural enhancing lesion extending out of the right neural foramen at L1–2. A right L1–2 hemilaminectomy and facetectomy with gross-total resection of the tumor was performed without complications. Neuroblastoma-like schwannoma was diagnosed based on histopathological examination of the biopsied tumor specimen. A postoperative course of serial examination and imaging was chosen based on a suspected benign postoperative course as in the case of a completely resected schwannoma. The authors present the novel case of neuroblastoma-like schwannoma at a lumbar spinal nerve root and describe the distinguishing pathological features of this rare lesion.

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Panagiotis Zogopoulos ◽  
Anastasios Venetikidis ◽  
Georgios Vretakos ◽  
Dimitrios Rologis

2001 ◽  
Vol 41 (3) ◽  
pp. 154-159 ◽  
Author(s):  
Koji YOSHIMOTO ◽  
Iwao TAKESHITA ◽  
Takuya INOUE ◽  
Tatsumi YAMAGUCHI ◽  
Masaru OHTA ◽  
...  

Neurosurgery ◽  
2005 ◽  
Vol 56 (3) ◽  
pp. 510-515 ◽  
Author(s):  
Takahiro Jinnai ◽  
Minoru Hoshimaru ◽  
Tsunemaro Koyama

Abstract OBJECTIVE: Spinal nerve sheath tumors arise from the spinal nerve root and grow along it. There are two sites at which the growth of a tumor is restricted: the dural aperture for the spinal nerve root and the intervertebral foramen. This article describes the growth pattern of a spinal nerve sheath tumor along the spinal nerve root at various spinal levels. METHODS: We retrospectively reviewed the records for 149 patients with spinal nerve sheath tumors who were treated between 1980 and 2001. Of these, 176 resected tumors were classified into five groups according to the relationship to the dura mater and/or the intervertebral foramen. RESULTS: Strictly intradural tumors compose 8% of nerve sheath tumors of the first two cervical nerve roots. The percentage of these tumors increased gradually from the high cervical region to the thoracolumbar region, where it was more than 80%. In contrast, the percentage of strictly extradural tumors gradually decreased from the rostral portion to the caudal portion. Similarly, a percentage of tumors extending outside the spinal canal decreased from the rostral portion to the caudal portion. These changes of the growth pattern may be explained by the anatomic features of the spinal nerve roots, which have a longer intradural component at the more caudal portion of the spinal axis. CONCLUSION: The anatomic relationship of a nerve sheath tumor with the dura mater and the intervertebral foramen varies depending on the level of the tumor. This knowledge may help us to create a strategy for total resection of a nerve sheath tumor.


2005 ◽  
Vol 23 (1) ◽  
pp. 27-30 ◽  
Author(s):  
Motohiro Inoue ◽  
Tatsuya Hojo ◽  
Tadashi Yano ◽  
Yasukazu Katsumi

We applied electroacupuncture to the spinal nerve root by inserting needles under x ray imaging in three cases with radicular sciatica, as a non-pharmacological substitute for lumbar spinal nerve block. In all three cases, symptoms were markedly reduced immediately after electroacupuncture to the spinal nerve root. The sustained effect was noticeably longer than that of spinal nerve blocks previously performed, in two out of the three cases. We suggest that descending inhibitory control, inhibitory control at the spinal level, inhibition of potential activity by hyperpolarisation of nerve endings, or changes in nerve blood flow may be involved in the mechanism of the effect of electroacupuncture to the spinal nerve root. These results suggest that electroacupuncture to the spinal nerve root may be superior to lumbar spinal nerve block when it is applied appropriately in certain cases of radicular sciatica, taking into consideration patient age, severity of symptoms and duration of the disorder.


Sign in / Sign up

Export Citation Format

Share Document