Asymmetric Synthesis of Chiral δ-lactones using BINAP-ruthenium(II) Complexes Hydrogenation Catalysts

2002 ◽  
Vol 2002 (11) ◽  
pp. 567-569 ◽  
Author(s):  
Yanjun Li ◽  
Taeko Izumi
Keyword(s):  
Asymmetric Synthesis ◽  
Ruthenium Complexes ◽  
Asymmetric Hydrogenation ◽  
Optical Purity ◽  
Hydrogenation Catalysts ◽  
Keto Acids ◽  
Chiralcel Od ◽  
High Yields

Asymmetric hydrogenation of keto-acids was accomplished by catalytic amounts of BINAP-ruthenium complexes to afford the corresponding δ-lactones in high yields. The optical purity of the synthesised δ-lactones was determined by chiralcel (OD) in the 9–56% range.

Reaction Mechanisms of Inorganic and Organometallic Systems

2007 ◽  
Author(s):  
Robert B. Jordan
Keyword(s):  
Electron Transfer ◽  
Heterogeneous Systems ◽  
Asymmetric Hydrogenation ◽  
Pressure Effects ◽  
General Level ◽  
Hydrogenation Catalysts ◽  
Methyl Transferase ◽  
Transfer Region ◽  
Previous Edition ◽  
Oxide Synthase

This third edition retains the general level and scope of earlier editions, but has been substantially updated with over 900 new references covering the literature through 2005, and 140 more pages of text than the previous edition. In addition to the general updating of materials, there is new or greatly expanded coverage of topics such as Curtin-Hammett conditions, pressure effects, metal hydrides and asymmetric hydrogenation catalysts, the inverted electron-transfer region, intervalence electron transfer, photochemistry of metal carbonyls, methyl transferase and nitric oxide synthase. The new chapter on heterogeneous systems introduces the basic background to this industrially important area. The emphasis is on inorganic examples of gas/liquid and gas/liquid/solid systems and methods of determining heterogeneity.

scholarly journals A two step synthesis of a key unit B precursor of cryptophycins by asymmetric hydrogenation

2011 ◽  
Vol 7 ◽  
pp. 243-245 ◽  
Author(s):  
Benedikt Sammet ◽  
Mathilde Brax ◽  
Norbert Sewald
Keyword(s):  
Asymmetric Hydrogenation ◽  
Synthetic Route ◽  
Reaction Conditions ◽  
High Yields

A novel highly enantioselective two step access to a unit B precursor of cryptophycins in good yields from commercially available starting materials has been developed. The key step is an asymmetric hydrogenation using the commercially available [(COD)Rh-(R,R)-Et-DuPhos]BF4 catalyst. The synthetic route provides the advantage of less synthetic steps, proceeds with high yields and enantioselectivity, and avoids hazardous reaction conditions.

Asymmetric synthesis by chiral ruthenium complexes

1980 ◽  
Vol 198 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Mario Bianchi ◽  
Ugo Matteoli ◽  
Gloria Menchi ◽  
Piero Frediani ◽  
Stefano Pratesi ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Ruthenium Complexes

Noncovalent Anchoring of Asymmetric Hydrogenation Catalysts on a New Mesoporous Aluminosilicate: Application and Solvent Effects

2004 ◽  
Vol 10 (22) ◽  
pp. 5829-5835 ◽  
Author(s):  
Chr�tien Simons ◽  
Ulf Hanefeld ◽  
Isabel W. C. E. Arends ◽  
Roger A. Sheldon ◽  
Thomas Maschmeyer
Keyword(s):  
Solvent Effects ◽  
Asymmetric Hydrogenation ◽  
Hydrogenation Catalysts ◽  
Mesoporous Aluminosilicate

Asymmetric synthesis by chiral ruthenium complexes

1977 ◽  
Vol 141 (1) ◽  
pp. 107-111 ◽  
Author(s):  
Mario Bianchi ◽  
Franco Piacenti ◽  
Piero Frediani ◽  
Ugo Matteoli ◽  
Carlo Botteghi ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Ruthenium Complexes
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