Three-component reaction between trivalent phosphorus nucleophiles, dialkyl acetylenedicarboxylates and (2,4-dinitrophenyl) acetic acid

2012 ◽  
Vol 36 (8) ◽  
pp. 497-499 ◽  
Author(s):  
Alireza Hassanabadi ◽  
Mohammad H. Mosslemin ◽  
Elaheh Abyar ◽  
Mohammad Taleb-Malamiri
Keyword(s):  
Acetic Acid ◽  
Trivalent Phosphorus ◽  
Dialkyl Acetylenedicarboxylates ◽  
Three Component Reaction

ChemInform Abstract: Three-Component Reaction Between Alkyl(aryl) Isocyanides and Dialkyl Acetylenedicarboxylates in the Presence of Ethyl Trifluoroacetate.

ChemInform ◽  
2011 ◽  
Vol 42 (40) ◽  
pp. no-no
Author(s):  
Khatereh Khandan-Barani ◽  
Malek Taher Maghsoodlou ◽  
Sayyed Mostafa Habibi-Khorasani ◽  
Nourallah Hazeri ◽  
Seyyed Sajad Sajadikhah
Keyword(s):  
Alkyl Aryl ◽  
Dialkyl Acetylenedicarboxylates ◽  
Three Component Reaction

scholarly journals Synthesis of spiro[dihydropyridine-oxindoles] via three-component reaction of arylamine, isatin and cyclopentane-1,3-dione

2013 ◽  
Vol 9 ◽  
pp. 8-14 ◽  
Author(s):  
Yan Sun ◽  
Jing Sun ◽  
Chao-Guo Yan
Keyword(s):  
Acetic Acid ◽  
Reaction Mechanism ◽  
Room Temperature ◽  
The Other ◽  
Other Hand ◽  
Three Component Reaction ◽  
High Yields

A fast and convenient protocol for the synthesis of novel spiro[dihydropyridine-oxindole] derivatives in satisfactory yields was developed by the three-component reactions of arylamine, isatin and cyclopentane-1,3-dione in acetic acid at room temperature. On the other hand the condensation of isatin with two equivalents of cyclopentane-1,3-dione gave 3,3-bis(2-hydroxy-5-oxo-cyclopent-1-enyl)oxindole in high yields. The reaction mechanism and substrate scope of this novel reaction is briefly discussed.

Nucleophilic Phosphine-Promoted Domino Reaction of Dialkyl Acetylenedicarboxylates and 3-Arylamino-1-methyl-1H-pyrrole-2,5-diones

Synthesis ◽  
2018 ◽  
Vol 50 (18) ◽  
pp. 3715-3722 ◽  
Author(s):  
Ying Han ◽  
Chao-Guo Yan ◽  
Chang-Zhou Liu ◽  
Yuan-Yuan Zhang ◽  
Jing Sun
Keyword(s):  
Room Temperature ◽  
Domino Reaction ◽  
Dimethyl Acetylenedicarboxylate ◽  
Dialkyl Acetylenedicarboxylates ◽  
Three Component Reaction

The three-component reaction of triphenylphosphine, dimethyl acetylenedicarboxylate and 3-arylamino-1-methyl-1H-pyrrole-2,5-diones in CH2Cl2 at room temperature resulted in functionalized 3-(triphenyl-λ5-phosphanylidene)succinates in nearly quantitative yields. However, tri(n-butyl)phosphine promoted reaction of dialkyl acetylenedicarboxylates and 3-arylamino-1-methyl-1H-pyrrole-2,5-diones in CH2Cl2 afforded functionalized pyrrolo[3,4-b]pyridine-4-carboxylates in satisfactory yields.

scholarly journals A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh
Keyword(s):  
Room Temperature ◽  
Facile Synthesis ◽  
One Pot ◽  
Pyrrole Derivatives ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Neutral Conditions

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.

Hantzsch-Like Three-Component Synthesis of 9,10-Dihydro-3H-10a-azaphenanthrene-2,4-dicarbonitriles

Synlett ◽  
2020 ◽  
Vol 31 (11) ◽  
pp. 1126-1128 ◽  
Author(s):  
Ismail A. Abdelhamid ◽  
Fatma M. Saleh ◽  
Hamdi M. Hassaneen
Keyword(s):  
Acetic Acid ◽  
Three Component Reaction ◽  
Bridgehead Nitrogen

A novel series of 9,10-dihydro-3H-10a-azaphenanthrene-2,4-dicarbonitrile derivatives that contain a bridgehead nitrogen were prepared by a three-component reaction of aldehydes, 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile, and 3-aminocrotononitrile in acetic acid.

Sign in / Sign up

Export Citation Format

Share Document