Solitary fibrous tumor with atypical features of the paravesical space: benign clinical course at the 10-years follow-up. Report of a case and review of the literature

Solitary fibrous tumors are rare mesenchymal tumors that typically arise from the pleura and rarely originate from the mesentery. We herein report a case involving a 66-year-old patient who presented with a mass on the left abdomen. This mass had been incidentally noticed 10 years earlier. The patient sometimes experienced abdominal pain. Physical examination revealed an irregular mass, which was resected. A biopsy of the mass revealed that it was a solitary fibrous tumor originating from the mesentery of the small intestine. The patient was discharged 1 week after surgery and had an uneventful clinical course throughout the 4-month postoperative follow-up.

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Synchronous Pulmonary Adenofibroma and Solitary Fibrous Tumor: Case Report and Review of the Literature

International Journal of Surgical Pathology ◽

10.1177/1066896918807302 ◽

2018 ◽

Vol 27 (3) ◽

pp. 322-327 ◽

Cited By ~ 2

Author(s):

Nicholas J. Olson ◽

Julianna M. Czum ◽

Francine B. de Abreu ◽

Konstantinos Linos ◽

Candice C. Black

Keyword(s):

Case Report ◽

Solitary Fibrous Tumor ◽

Clinical Course ◽

Significant Proportion ◽

Review Of The Literature ◽

Single Patient ◽

Rare Neoplasm ◽

Fibrous Tumor ◽

Aggressive Clinical Course

Pulmonary adenofibroma (PAF) is a rare neoplasm that may be related to solitary fibrous tumor (SFT). A subset of PAFs harbor the NAB2-STAT6 fusion that is typical of SFT, but a significant proportion do not. Their distinction is clinically important as SFTs can potentially have an aggressive clinical course, while there has been no report of a PAF behaving in a malignant fashion. We report a case of a 60-year-old male who developed a SFT and PAF in the same lung. The SFT harbored a NAB2-STAT6 fusion, while the PAF did not have any identifiable fusion. This case represents the first instance of a single patient with both of these tumors occurring simultaneously in the same lung.

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Synchronous Pancreatic and Pulmonary Metastases from Solitary Fibrous Tumor of the Pleura: Report of a Case

Tumori Journal ◽

10.5301/tj.5000592 ◽

2017 ◽

Vol 103 (1_suppl) ◽

pp. S9-S11 ◽

Cited By ~ 1

Author(s):

Nicola Tamburini ◽

Nicolò Fabbri ◽

Gabriele Anania ◽

Pio Maniscalco ◽

Francesco Quarantotto ◽

...

Keyword(s):

Solitary Fibrous Tumor ◽

Pulmonary Metastases ◽

Clinical Course ◽

Good Prognosis ◽

Pancreatic Metastasis ◽

Case Presentation ◽

First Case ◽

Fibrous Tumor ◽

Uncommon Tumor

Introduction Solitary fibrous tumor of the pleura is an uncommon tumor with an indolent course and a good prognosis after surgical resection. However, the tumor occasionally follows an unpredictable clinical course and malignant transformation has been reported to increase the rate of local recurrence. Solitary extrathoracic metastasis from solitary fibrous tumor of the pleura is an uncommon finding. Case Presentation In this case report we present the first case of a synchronous single pulmonary and pancreatic metastasis treated with minimally invasive surgery. Conclusions Pancreatic recurrence should be considered in the postoperative follow-up in patients with solitary fibrous tumor of the pleura.

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Solitary Fibrous Tumor of the Pleura: Surgery and Clinical Course in 18 Cases

Asian Cardiovascular and Thoracic Annals ◽

10.1177/0218492309338103 ◽

2009 ◽

Vol 17 (4) ◽

pp. 378-381 ◽

Cited By ~ 4

Author(s):

Alessandro Bini ◽

Jury Brandolini ◽

Fabio Davoli ◽

Giampiero Dolci ◽

Francesco Sellitri ◽

...

Keyword(s):

Surgical Treatment ◽

Solitary Fibrous Tumor ◽

Clinical Course ◽

Survival Rates ◽

Pleural Mesothelioma ◽

Perioperative Mortality ◽

Solitary Fibrous Tumors ◽

Fibrous Tumor

Solitary fibrous tumors of the pleura are very rare neoplasms that can sometimes present with malignant features. Between 1984 and 2007, 18 cases were treated in our institution. There were 7 men and 11 women, with a median age of 56 years (range, 33-77 years). All patients underwent surgical treatment. Except for one case with hemangiopericytic features, all tumors were histologically the fibrous type of pleural mesothelioma. Resections were radical and there were no recurrences. There was no perioperative mortality. The outcome was excellent, and all patients have been followed up continuously. Survival rates at 3, 5, and 10 years were calculated as 86.7%, 75%, and 66.7%. One patient died after 18 months (malignant type of solitary fibrous tumor), and 2 died of unrelated disease after 24 and 53 months. Surgery is the treatment of choice, and careful long-term clinical follow-up is required.

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Intracranial Solitary Fibrous Tumor of the Skull Base: 2 Cases and Systematic Review of the Literature

World Neurosurgery ◽

10.1016/j.wneu.2021.02.026 ◽

2021 ◽

Vol 149 ◽

pp. e345-e359

Author(s):

Sricharan Gopakumar ◽

Visish M. Srinivasan ◽

Caroline C. Hadley ◽

Adrish Anand ◽

Marc Daou ◽

...

Keyword(s):

Systematic Review ◽

Skull Base ◽

Solitary Fibrous Tumor ◽

Review Of The Literature ◽

Fibrous Tumor

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Pazopanib-associated secondary adrenal insufficiency in a patient with malignant solitary fibrous tumor

Journal of Oncology Pharmacy Practice ◽

10.1177/10781552211016081 ◽

2021 ◽

pp. 107815522110160

Author(s):

Muhammed Muhiddin Er ◽

Murat Araz ◽

Meryem Karabacak ◽

Muzaffer Uğraklı ◽

Melek Karakurt Eryılmaz ◽

...

Keyword(s):

Adrenal Insufficiency ◽

Solitary Fibrous Tumor ◽

Single Case ◽

Soft Tissue Sarcomas ◽

Pituitary Hormones ◽

Secondary Adrenal Insufficiency ◽

Primary Adrenal Insufficiency ◽

Hypoglycemic Attack ◽

Fibrous Tumor

Introduction Pazopanib is an agent that is being successfully used in soft tissue sarcomas. Some endocrine side effects may develop during pazopanib treatment. Here, we presented a case diagnosed with secondary adrenal insufficiency while being investigated for etiology of hypoglycemia which developed after pazopanib. Case report A 69-year-old male patient was operated in June 2019 due to a lung mass 26 × 18 × 10 cm in size. Pathological diagnosis revealed a solitary fibrous tumor with malignant behavior. The patient received three lines of chemotherapy. After pazopanib treatment, a hypoglycemic attack was reported. Management and outcome: Blood cortisol and ACTH (Adrenocorticotropic hormone) levels were not increased at the time of the hypoglycemic attack, and levels of other pituitary hormones were found to be normal. Electrolyte levels were in normal range. Since the counteracting hormone did not reach a sufficient level, it was considered secondary adrenal insufficiency. Hypoglycemic attacks did not occur during follow-up while taking steroid therapy and pazopanib. Discussion A single case of primary adrenal insufficiency has been reported in the literature. We here present a case who developed hypoglycemia after pazopanib and was diagnosed with drug-associated secondary adrenal insufficiency. When hypoglycemia develops during pazopanib treatment, we must be aware of adrenal insufficiency.

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Solitary fibrous tumor of the lacrimal sac: A rare entity and a brief review of the literature

Indian Journal of Ophthalmology - Case Reports ◽

10.4103/ijo.ijo_158_21 ◽

2021 ◽

Vol 1 (4) ◽

pp. 731

Author(s):

Deepsekhar Das ◽

Sahil Agrawal ◽

Aishwarya Rathod ◽

Sujeeth Modaboyina ◽

Seema Sen ◽

...

Keyword(s):

Solitary Fibrous Tumor ◽

Rare Entity ◽

Review Of The Literature ◽

Lacrimal Sac ◽

Fibrous Tumor

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Orbital Solitary Fibrous Tumor: A Case Report and Review of the Literature

Pathology & Oncology Research ◽

10.1007/s12253-008-9055-7 ◽

2008 ◽

Vol 14 (2) ◽

pp. 213-217 ◽

Cited By ~ 20

Author(s):

Giuseppe Leoncini ◽

Vincenza Maio ◽

Marco Puccioni ◽

Alessandro Franchi ◽

Vincenzo De Giorgi ◽

...

Keyword(s):

Case Report ◽

Solitary Fibrous Tumor ◽

Review Of The Literature ◽

Fibrous Tumor

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Intrapulmonary Solitary Fibrous Tumor of the Lung: A Rare Case Presentation

The Journal of Medical Sciences ◽

10.5005/jp-journals-10045-0034 ◽

2016 ◽

Vol 2 (2) ◽

pp. 42-44

Author(s):

S Parinita ◽

KN Mohan Rao ◽

Vivek LNU

Keyword(s):

Solitary Fibrous Tumor ◽

Rare Case ◽

Pleural Cavity ◽

Visceral Pleura ◽

Review Of The Literature ◽

Case Presentation ◽

Fibrous Tumor

ABSTRACT Localized fibrous tumors of the lung arise from the visceral pleura and are pedunculated. They also project into the pleural cavity. The tumor with an entirely pulmonary location is extremely rare. We present here a rare case of intrapulmonary localized fibrous tumor with review of the literature. How to cite this article Parinita S, Rao KNM, Vivek. Intrapulmonary Solitary Fibrous Tumor of the Lung: A Rare Case Presentation. J Med Sci 2016;2(2):42-44.

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Solitary Fibrous Tumors of the Chest: An Analysis of Fifty Patients

Frontiers in Oncology ◽

10.3389/fonc.2021.697156 ◽

2021 ◽

Vol 11 ◽

Author(s):

Jingwen Zhang ◽

Jumin Liu ◽

Zhihao Zhang ◽

Beizong Tian

Keyword(s):

Solitary Fibrous Tumor ◽

Chest Tightness ◽

Ki 67 ◽

Imaging Characteristics ◽

Enhanced Ct ◽

The Common ◽

The Difference ◽

Low Incidence ◽

Fibrous Tumor

BackgroundA solitary fibrous tumor of the chest (SFTC) is a subtype of solitary fibrous tumor (SFT) with a low incidence rate. The purpose of this study is to analyze the diagnosis and treatment of SFTC and the difference between benign and malignant solitary fibrous tumor of the pleura (SFTP) to improve the understanding of this rare disease.MethodsA retrospective analysis of fifty patients with SFTC (33 cases in the pleura and 17 in the lung) was performed. Clinical and imaging characteristics, pathological features, and treatment follow-up outcomes were analyzed.ResultsThe common symptoms of the 50 patients included a cough, expectoration, chest tightness, fever, and chest pain. Space occupying lesions were found via plain computed tomography (CT) and enhanced CT was used for enhancement of the tumors. It was also found that 18 cases had necrosis, and 5 cases had calcification. The histopathology results showed that frequent nuclear division, obvious morphological variation, necrosis, and the high expression of Ki-67 cells are markers of malignant SFTC. There were significant differences in age, chest tightness, necrotic foci in CT, and expression of Ki-67 between the benign and malignant SFTP cases. All the patients who received treatment were given an excellent prognosis.ConclusionA combination of enhanced CT, histopathology, and immunohistochemistry can be used for the accurate diagnosis of SFTC. Advanced age, chest tightness, necrotic foci in CT, and a high Ki-67 index were more likely to be malignant SFTP. Operation and radiofrequency ablation can provide favorable outcomes for both benign and malignant SFTC.

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