1H-MRS Evaluation of Therapeutic Effect of Neural Stem Cell Transplantation on Alzheimer's disease in AβPP/PS1 Double Transgenic Mice

2012 ◽  
Vol 28 (1) ◽  
pp. 71-80 ◽  
Author(s):  
Shuang-Qing Chen ◽  
Qing Cai ◽  
Yu-Ying Shen ◽  
Pei-Jun Wang ◽  
Gao-Jun Teng ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cell ◽  
Transgenic Mice ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Neural Stem Cell ◽  
Therapeutic Effect ◽  
1H Mrs ◽  
Double Transgenic Mice

scholarly journals New Prospects for Stem Cell Therapy in Alzheimer’s Disease

2021 ◽  
Author(s):  
Kun Jiang ◽  
Yongqi Zhu ◽  
Lei Zhang
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Stem Cell Therapy ◽  
Amyloid Β ◽  
Amyloid Β Protein ◽  
Therapy Strategies

Alzheimer’s disease (AD) is a kind of neurodegenerative disease with insidious onset and progressive progression. The etiology of AD may be related to the loss of neurons, astrocytes, and microglial in the nervous system. Exogenous stem cell transplantation has brought hope to the treatment of AD. Stem cell transplantation can reduce amyloid β-protein (Aβ) deposition and Tau phosphorylation, and provide secretory factor support to improve learning and memory deficits. The purpose of this review is to provide an overview of the relationship between different stem cell species and the treatment of AD, and also summarize current experimental stem cell therapy strategies and their potential clinical applications in the future.

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