Longitudinal Healthcare Utilization and Costs in Parkinson’s Disease: Pre-Diagnosis to 9 Years After

2021 ◽  
pp. 1-10
Author(s):  
Ming Li Emily Soh ◽  
Xiumin Shermyn Neo ◽  
Seyed Ehsan Saffari ◽  
Sheng Yong Aidan Wong ◽  
Ganga Ganesan ◽  
...  

Background: There is currently insufficient long-term data on costs of treatment in patients with Parkinson’s disease (PD), which is chronic and progressive, and associated with substantial healthcare costs. Identifying patterns in healthcare utilization and cost may illuminate further discussion on early intervention. Objective: To characterize long-term healthcare utilization and costs of PD in newly diagnosed patients managed by movement disorder specialists. Methods: Using a longitudinal matched-cohort study of linked data from the National Neuroscience Institute Parkinson’s disease and Movement Disorder and healthcare administrative databases in Singapore from 2008–2017, we compared healthcare utilization and costs between patients and controls matched on age, sex, race, and Charlson Comorbidity Index score. Results: 1,162 patients met study inclusion criteria and 1,157 matched controls were identified. The total mean annual healthcare cost (at 2017 costs) was significantly increased in patients compared to controls from years 1–9 post-diagnosis. The increased cost was observed 2 years before diagnosis (USD2322 vs. 2052; p <  0.001). Mean annual cost attributable to PD increased from USD1854 at 1-year post-diagnosis to USD2652 at 9 years. Over 9 years, average costs were significantly higher across all domains of healthcare utilization except primary care—cost of intermediate and long-term care was increased by a factor of 2.5, specialist care by 2.3, emergency department visits by 1.6, and hospital admissions by 1.3. Conclusion: PD results in higher healthcare utilization and costs. Pre-diagnosis increase in healthcare utilization observed in patients supports the presence of prodromal PD symptoms and may present an opportunity for early diagnosis.

2016 ◽  
Vol 44 (2) ◽  
pp. 92-97 ◽  
Author(s):  
Peter J. Barbour ◽  
Jill Arroyo ◽  
Star High ◽  
Lisa B. Fichera ◽  
Marie M. Staska-Pier ◽  
...  

2020 ◽  
Vol Volume 12 ◽  
pp. 23-30 ◽  
Author(s):  
Farid Chekani ◽  
Holly M Holmes ◽  
Michael L Johnson ◽  
Hua Chen ◽  
Jeffrey T Sherer ◽  
...  

2018 ◽  
Vol 21 ◽  
pp. S204
Author(s):  
F Chekani ◽  
ML Johnson ◽  
H Chen ◽  
JT Sherer ◽  
HM Holmes ◽  
...  

Drugs & Aging ◽  
2012 ◽  
Vol 30 (1) ◽  
pp. 19-22 ◽  
Author(s):  
Nathan Herrmann ◽  
Connie Marras ◽  
Hadas D. Fischer ◽  
Xuesong Wang ◽  
Geoff M. Anderson ◽  
...  

2002 ◽  
Vol 14 (9) ◽  
pp. 23-29 ◽  
Author(s):  
Sue Thomas ◽  
Doug MacMahon

2021 ◽  
pp. 073346482098703
Author(s):  
Nazia Rashid ◽  
Andrew Shim ◽  
Sherry Andes ◽  
Sonja Quale ◽  
Victor Abler

This study assessed treatment change patterns in Parkinson’s disease psychosis (PDP) residents receiving antipsychotic (AP) therapies in U.S. long-term care (LTC) facilities. Residents with PDP in LTC between 01/01/13 and 06/30/16 were identified with ≥1 claim of psychosis, hallucinations, or delusions after PD diagnosis. Treatment patterns were evaluated during the 12 months post index. We identified 864 PDP residents: 408 (47.2%) on AP therapy and 456 (52.8%) on no AP therapy. A total of 335 residents (82.1%) continued, 13 (3.2%) discontinued, 11 (2.7%) switched, and 49 (12.0%) augmented (used ≥2 APs) their index AP therapy. Based on the multivariate regression analysis, younger age, male gender, anemia, anxiolytic use or anxiety, sedatives/hypnotic use, bladder disorders including urinary tract infections, coronary conditions, diabetes, hypertension, and dementia were associated with a higher likelihood of treatment change. Understanding the factors associated with treatment change may inform ways to improve management of PDP in the U.S. LTC setting.


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