scholarly journals Sugammadex for the reversal of muscle relaxation in general anaesthesia: a systematic review and economic assessment

2010 ◽  
Vol 14 (39) ◽  
Author(s):  
D Chambers ◽  
M Paulden ◽  
F Paton ◽  
M Heirs ◽  
S Duffy ◽  
...  
Author(s):  
T. Brighton Dzikiti

Intravenous anaesthesia is gradually becoming popular in veterinary practice. Traditionally, general anaesthesia is induced with intravenous drugs and then maintained with inhalation agents. Inhalation anaesthetic agents cause more significant dose-dependent cardiorespiratory depression than intravenous anaesthetic drugs, creating a need to use less of the inhalation anaesthetic agents for maintenance of general anaesthesia by supplementing with intravenous anaesthesia drugs. Better still, if anaesthesia is maintained completely with intravenous anaesthetic drugs, autonomic functions remain more stable intra-operatively. Patient recovery from anaesthesia is smoother and there is less pollution of the working environment than happens with inhalation anaesthetic agents. Recently, a number of drugs with profiles (pharmacokinetic and pharmacodynamic) suitable for prolonged intravenous anaesthesia have been studied, mostly in humans and, to a certain extent, in dogs and horses. There is currently very little scientific information on total intravenous anaesthesia in goats, although, in the past few years, some scholarly scientific articles on drugs suitable for partial intravenous anaesthesia in goats have been published. This review article explored the information available on drugs that have been assessed for partial intravenous anaesthesia in goats, with the aim of promoting incorporation of these drugs into total intravenous anaesthesia protocols in clinical practice. That way, balanced anaesthesia, a technique in which drugs are included in anaesthetic protocols for specific desired effects (hypnosis, analgesia, muscle relaxation, autonomic stabilisation) may be utilised in improving the welfare of goats undergoing general anaesthesia.


This chapter summarizes the different techniques available for analgesia, anaesthesia, and sedation in dentistry. This includes the use of benzodiazepines while highlighting the indications and contraindications for each technique and approach. The varying methods of administration of local analgesia are outlined, with information on the commonly used preparations and techniques. The use of both oral and intravenous sedation is discussed, including important points on drug interactions and reversal agents. This chapter considers the triad of unconsciousness, muscle relaxation, and analgesia that makes up general anaesthesia and details the drugs used to achieve this in a hospital setting.


2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Stefan Schraag ◽  
Lorenzo Pradelli ◽  
Abdul Jabbar Omar Alsaleh ◽  
Marco Bellone ◽  
Gianni Ghetti ◽  
...  

2020 ◽  
Vol 124 (4) ◽  
pp. 480-495 ◽  
Author(s):  
Alan Tung ◽  
Nicholas A. Fergusson ◽  
Nicole Ng ◽  
Vivien Hu ◽  
Colin Dormuth ◽  
...  

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