scholarly journals Randomized comparison of sugammadex and neostigmine for reversal of rocuronium-induced muscle relaxation in morbidly obese undergoing general anaesthesia

2012 ◽  
Vol 108 (2) ◽  
pp. 236-239 ◽  
Author(s):  
T. Gaszynski ◽  
T. Szewczyk ◽  
W. Gaszynski
Keyword(s):  
General Anaesthesia ◽  
Muscle Relaxation ◽  
Morbidly Obese

scholarly journals Intravenous anaesthesia in goats: A review

2013 ◽  
Vol 84 (1) ◽  
Author(s):  
T. Brighton Dzikiti
Keyword(s):  
General Anaesthesia ◽  
Muscle Relaxation ◽  
Scientific Information ◽  
Working Environment ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Anaesthetic Agents ◽  
Inhalation Anaesthetic ◽  
Intravenous Anaesthetic ◽  
Balanced Anaesthesia

Intravenous anaesthesia is gradually becoming popular in veterinary practice. Traditionally, general anaesthesia is induced with intravenous drugs and then maintained with inhalation agents. Inhalation anaesthetic agents cause more significant dose-dependent cardiorespiratory depression than intravenous anaesthetic drugs, creating a need to use less of the inhalation anaesthetic agents for maintenance of general anaesthesia by supplementing with intravenous anaesthesia drugs. Better still, if anaesthesia is maintained completely with intravenous anaesthetic drugs, autonomic functions remain more stable intra-operatively. Patient recovery from anaesthesia is smoother and there is less pollution of the working environment than happens with inhalation anaesthetic agents. Recently, a number of drugs with profiles (pharmacokinetic and pharmacodynamic) suitable for prolonged intravenous anaesthesia have been studied, mostly in humans and, to a certain extent, in dogs and horses. There is currently very little scientific information on total intravenous anaesthesia in goats, although, in the past few years, some scholarly scientific articles on drugs suitable for partial intravenous anaesthesia in goats have been published. This review article explored the information available on drugs that have been assessed for partial intravenous anaesthesia in goats, with the aim of promoting incorporation of these drugs into total intravenous anaesthesia protocols in clinical practice. That way, balanced anaesthesia, a technique in which drugs are included in anaesthetic protocols for specific desired effects (hypnosis, analgesia, muscle relaxation, autonomic stabilisation) may be utilised in improving the welfare of goats undergoing general anaesthesia.

Analgesia, anaesthesia, and sedation

2020 ◽  
pp. 623-645
Keyword(s):  
Drug Interactions ◽  
General Anaesthesia ◽  
Muscle Relaxation ◽  
Hospital Setting ◽  
Intravenous Sedation ◽  
Local Analgesia ◽  
Reversal Agents

This chapter summarizes the different techniques available for analgesia, anaesthesia, and sedation in dentistry. This includes the use of benzodiazepines while highlighting the indications and contraindications for each technique and approach. The varying methods of administration of local analgesia are outlined, with information on the commonly used preparations and techniques. The use of both oral and intravenous sedation is discussed, including important points on drug interactions and reversal agents. This chapter considers the triad of unconsciousness, muscle relaxation, and analgesia that makes up general anaesthesia and details the drugs used to achieve this in a hospital setting.

scholarly journals Anaesthesia of a Patient Allergic to Multiple-Anaesthesia Drugs: A Case Report

2021 ◽  
pp. 1-3
Author(s):  
Estebe JP ◽  
Saleh O ◽  
Bensalah K ◽  
Khene ZE ◽  
Rochefort-Morel C ◽  
...  
Keyword(s):  
Case Report ◽  
Postoperative Pain ◽  
General Anaesthesia ◽  
Deep Sedation ◽  
Muscle Relaxation ◽  
Multiple Drug ◽  
Close Collaboration ◽  
Robot Assisted ◽  
Robot Assisted Surgery

Anaesthesia of multiple drug allergic patients may be very challenging. Especially with a patient showing allergic signs for multiple main anaesthesia drugs and scheduled for laparoscopic robot-assisted surgery. We report the case of a 65-year-old man. The systemic allergic screenings concluded with rocuronium, atracurium, cisatracurium, propofol, chlorhexidine, latex and betalactamine contraindications. Sufentanil to be used with extreme precautions. General anaesthesia was performed with an OFA protocol. Muscle relaxation was obtained by deep sedation. A close collaboration with the surgeons made it possible to carry out the procedure with a perfect control of the postoperative pain.

scholarly journals Clinical evaluation of general anaesthesia in pigeons using a combination of ketamine and diazepam

2012 ◽  
Vol 83 (1) ◽  
Author(s):  
Aidin Azizpour ◽  
Yashar Hassani
Keyword(s):  
General Anaesthesia ◽  
Normal Saline ◽  
Muscle Relaxation ◽  
Saline Group ◽  
Clinical Effects ◽  
Normal Saline Group ◽  
Rapid Induction ◽  
The Difference ◽  
Induction Of Anaesthesia ◽  
Group D

This study was undertaken to investigate the clinical effects of ketamine, diazepam and a ketamine and diazepam combination in the general anaesthesia of pigeons. Thirty-two pigeons of both sexes with body weights ranging from 280 g to 300 g were allocated randomly to four groups comprising eight birds each. Group D received a 0.5 mL mixture of diazepam (0.2 mg/kg) and normal saline, group K a 0.5 mL mixture of ketamine 5% (30 mg/kg) and normal saline, group D, group KD a 0.5 mL mixture of ketamine 5% (10 mg/kg), diazepam (0.2 mg/kg) and normal saline, whilst group C (control) received 0.5 mL of normal saline only. Each mixture was administered intramuscularly.Under standard operating room conditions, general anaesthesia was not observed in group C (normal saline alone). In group D, sedation and muscle relaxation without complete loss of consciousness was observed. Induction time of anaesthesia in group KD was significantly quicker than group K (p < 0.05). Duration of anaesthesia in group KD was significantly longer than group K (p < 0.05). Recovery took longer in group KD in comparison with group K, but the difference was not statistically significant (p > 0.05). The birds in group KD were calm and sedated, with good muscle relaxation, whilst in group K the birds were excited and showed a drop in body temperature.According to the results of this study, the combination of low dose ketamine hydrochloride (HCL) and diazepam overcame the adverse effects of ketamine alone. This combination produced a more rapid induction of anaesthesia, as well as an increase in anaesthesia duration, with good muscle relaxation and a smooth and slow recovery. Use of a combination of ketamine HCL given at 10 mg/kg and diazepam given at 0.2 mg/kg for anaesthesia in pigeons is therefore recommended.

scholarly journals Evaluation of general anesthesia induced by propofol, ketamine protocol in rabbits premedicated with diazepam

2014 ◽  
Vol 38 (2) ◽  
pp. 100-107
Author(s):  
Areej Ali Atiyah
Keyword(s):  
Heart Rate ◽  
Body Temperature ◽  
General Anesthesia ◽  
Respiratory Rate ◽  
General Anaesthesia ◽  
Intramuscular Injection ◽  
Muscle Relaxation ◽  
Healthy Male ◽  
Male Adult ◽  
Wave Morphology

The present study was designed to evaluate the efficacy of diazepam-propofol-Ketamine protocol for induction of general anaesthesia in rabbits. The experiment was conducted on seventeen healthy male adult local rabbits weighting 0.9-1.5 kg. Rabbits were given protocol, Diazepam 1mg/kg B.W. by intramuscular injection then 15 minutes later propofol 10 mg/kg B.W. as bolus slow intravenous injection and ketamine 25 mg/kg BW by intramuscular injection. Several parameters included respiratory rate, body temperature and heart rate were recorded before injection of drugs and after giving the anesthetic protocol at 0, 5, 10, 15, 20, 30, 45, 60, 75 and 90 minutes. The results showed that the anaesthesia with diazepam, propofol and Ketamine protocol in rabbits was suitable as it produced reliable surgical anaesthesia, good analgesia and muscle relaxation with minimal changes on the wave morphology of the cardiac muscle.

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