scholarly journals Parotitis in a pemphigus vulgaris patient with widespread oral lesions: a rare or underdiagnosed condition?

Mucosa ◽  
2021 ◽  
pp. 23-26
Author(s):  
Züleyha ÖZGEN ◽  
Elif COMERT OZER ◽  
Dilek SEÇKİN
Author(s):  
Tayna Soares De Oliveira ◽  
Lucas Lavareze Dos Reis ◽  
Thuany Servare De Lima ◽  
Danielle Resende Camisasca ◽  
Tânia Regina Grão Velloso ◽  
...  

1995 ◽  
Vol 88 (1) ◽  
pp. 49-53
Author(s):  
Haruo HIRAKAWA ◽  
Yukiko IINO

2018 ◽  
Vol 2 (2) ◽  
pp. 117-124
Author(s):  
Indra Gunawan ◽  
Riani Setiadhi

Background : Pemphigus Vulgaris (PV) is an autoimmune intraepithelial blistering disease involving the skin and mucous membranes. Oral lesions could be the first sign of the disease followed by the involvement of skin and other mucosa sites.Objectives : This is oral manifestations of pemphigus vulgaris case report, intended to help clinicians to recognize and treat the oral lesions.Case Reported : Male 27 yo admitted to RSUP Dr.Hasan Sadikin hospital with multiple blisters on the skin and oral mucosa, was diagnosed with Pemphigus Vulgaris.Case Management : Patient was treated with steroid mouth wash and oral paste. After two months of treatment, the patient was fully recovered from oral lesion.Discussion : In PV, autoantibodies are produced against desmosomes spesifically desmoglein 3 which responsible for holding the cells of the epithelium together. The loss of adhesive function due to anti Dsg 3 antibodies result in bulla formation on the oral mucosa.The aetiology for PV is still uncertain. Conclusion :Early recognition and treatment of oral lesions is important as it may prevent skin involvement. Early treatment, patient’s compliance and multi disciplinal teamwork ensure the treatment succes for this disease


2017 ◽  
Vol 177 (6) ◽  
pp. 1583-1589 ◽  
Author(s):  
S. Kumar ◽  
D. De ◽  
S. Handa ◽  
R.K. Ratho ◽  
S. Bhandari ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Diana Kuriachan ◽  
Rakesh Suresh ◽  
Mahija Janardhanan ◽  
Vindhya Savithri

Pemphigus is a group of potentially fatal dermatoses with both cutaneous and oral manifestations. Characterized by the appearance of vesicle or bullae, their manifestations in the oral cavity often precede those on the skin by many months or may remain as the only symptoms of the disease. It is therefore important that the oral manifestations of the disease are recognized on time, to make a proper diagnosis and initiate timely treatment. Here we present a case of Pemphigus Vulgaris (PV) that presented with oral lesions at multiple sites including tongue, to highlight the importance of timely recognition of the oral lesions during routine dental practice for the diagnosis and management of this disease.


Author(s):  
Vinay K. N. ◽  
Gouhare Afshan

<p class="abstract"><strong>Background:</strong> Pemphigus vulgaris is an autoimmune vesiculobullous disease characterized by vesicles and or bullae affecting skin and mucosa. Oral lesions are the first manifestation of the disease in majority of cases according to literature. This study is conducted to know the prevalence of oral lesions in pemphigus vulgaris patients at the time of presentation.</p><p class="abstract"><strong>Methods:</strong> This was a retrospective study. Departmental records were evaluated from January 2013 to January 2018. All the demographic data of pemphigus vulgaris patients at the time of first presentation, duration of disease, were assessed and tabulated. The clinical data of these patients during their subsequent visits to clinic were assessed for development of new oral lesions during course of disease.<strong></strong></p><p class="abstract"><strong>Results:</strong> Total number of patients were 55. The mean age was 42.5 years. 12 (21.8%) were males and 4 (78.1%) were females. Out of 55 patients 37 (67.27%) cases had oral involvement and 18 (32.72%) cases did not have oral lesions at the time of presentation. Out of 37 patients who had oral lesions, 34 (91.89%) patients had both oral and skin lesions and 3 (08.10%) patients had only oral lesions at the time of presentation. Out of the18 patients with no oral lesions, 3 (16.66%) patients developed oral lesions within 3 months. Total number of patients with oral lesions out of 55 were 40 (72.7%).</p><p class="abstract"><strong>Conclusions:</strong> Our study shows that oral lesions as initial manifestation of pemphigus vulgaris is 67.2%.</p>


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