scholarly journals Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

Haematologica ◽  
2019 ◽  
Vol 105 (3) ◽  
pp. 640-651 ◽  
Author(s):  
Marlijn Hoeks ◽  
Ge Yu ◽  
Saskia Langemeijer ◽  
Simon Crouch ◽  
Louise de Swart ◽  
...  
2014 ◽  
Vol 38 (5) ◽  
pp. 557-563 ◽  
Author(s):  
Michel Delforge ◽  
Dominik Selleslag ◽  
Yves Beguin ◽  
Agnès Triffet ◽  
Philippe Mineur ◽  
...  

2011 ◽  
Vol 9 (1) ◽  
pp. 65-75 ◽  
Author(s):  
David P. Steensma

The appropriate role of iron chelation therapy in the management of patients with myelodysplastic syndromes (MDS) is currently controversial. Some investigators interpret data to indicate that careful attention to iron parameters, with early initiation of iron chelation in patients with evidence suggesting transfusion-associated iron overload, is an important component of high-quality MDS patient care. Other physicians are more skeptical, noting that chelation can be cumbersome or costly, has associated risks, and has not yet been shown to reduce morbidity or mortality in the MDS setting. This article reviews the extent to which iron chelation therapy might be either an important clinical intervention in MDS or a distraction from more pressing clinical concerns.


2017 ◽  
Vol 55 ◽  
pp. S164
Author(s):  
D. Singhal ◽  
R. Chhetri ◽  
L.A. Wee ◽  
M. Kutyna ◽  
S. Nath ◽  
...  

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