Toward resolving the unsettled role of iron chelation therapy in myelodysplastic syndromes

2014 ◽  
Vol 14 (7) ◽  
pp. 817-829 ◽  
Author(s):  
Drorit G Merkel ◽  
Arnon Nagler
Keyword(s):  
Myelodysplastic Syndromes ◽  
Chelation Therapy ◽  
Iron Chelation ◽  
Iron Chelation Therapy

The Role of Iron Chelation Therapy for Patients With Myelodysplastic Syndromes

2011 ◽  
Vol 9 (1) ◽  
pp. 65-75 ◽  
Author(s):  
David P. Steensma
Keyword(s):  
Iron Overload ◽  
Myelodysplastic Syndromes ◽  
Chelation Therapy ◽  
Iron Chelation ◽  
Clinical Intervention ◽  
Iron Chelation Therapy ◽  
Careful Attention ◽  
High Quality ◽  
Iron Parameters

The appropriate role of iron chelation therapy in the management of patients with myelodysplastic syndromes (MDS) is currently controversial. Some investigators interpret data to indicate that careful attention to iron parameters, with early initiation of iron chelation in patients with evidence suggesting transfusion-associated iron overload, is an important component of high-quality MDS patient care. Other physicians are more skeptical, noting that chelation can be cumbersome or costly, has associated risks, and has not yet been shown to reduce morbidity or mortality in the MDS setting. This article reviews the extent to which iron chelation therapy might be either an important clinical intervention in MDS or a distraction from more pressing clinical concerns.

Role of T2* Magnetic Resonance in Monitoring Iron Chelation Therapy

2009 ◽  
Vol 122 (2-3) ◽  
pp. 146-154 ◽  
Author(s):  
John-Paul Carpenter ◽  
Dudley J. Pennell
Keyword(s):  
Magnetic Resonance ◽  
Chelation Therapy ◽  
Iron Chelation ◽  
Iron Chelation Therapy
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