A rare presentation of primary leiomyosarcoma of ovary in a young woman

Hyperandrogenism is a relatively common clinical problem. However, severe hyperandrogenism causing virilisation is rare. A 27-year-old woman presented with generalised hirsutism, clitoromegaly, breast atrophy and secondary amenorrhoea. She had serum testosterone levels elevated to the adult male range. Administration of gonadotropin-releasing hormone (GnRH) analogue resulted in >50% suppression of serum testosterone which was suggestive of luteinising hormone-dependent ovarian hyperandrogenism. Imaging studies of abdomen and pelvis were normal, and ovarian venous sampling failed to show a gradient between the two sides. A presumptive diagnosis of ovarian hyperthecosis was, therefore, considered. Medical treatment with GnRH analogue and combined oral contraceptive pills was initiated to which an excellent clinical and biochemical response was noted. This case highlights a rare presentation of ovarian hyperthecosis in a young woman with severe hyperandrogenism mimicking a virilising neoplasm.

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Primary Pulmonary Leiomyosarcoma: A Rare Presentation

Asian Cardiovascular and Thoracic Annals ◽

10.1177/021849230000800120 ◽

2000 ◽

Vol 8 (1) ◽

pp. 67-69 ◽

Cited By ~ 3

Author(s):

Madhava Janardhan Naik ◽

Chong Hee Lim ◽

Thirugnanam Agasthian

Keyword(s):

Unusual Case ◽

Lower Lobe ◽

Cystic Mass ◽

Left Lower Lobe ◽

Resected Specimen ◽

Good Recovery ◽

Rare Presentation ◽

Lung Histology ◽

Primary Leiomyosarcoma

An unusual case of primary leiomyosarcoma presenting as a cystic mass is reported. An 86-year-old man underwent resection of a large cystic mass measuring 15 cm in diameter, arising from the left lower lobe of the lung. Histology of the resected specimen showed primary pulmonary leiomyosarcoma. The patient made a good recovery.

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Cholesterol granuloma of the maxillary sinus: a forgotten entity

Pediatria i Medycyna Rodzinna ◽

10.15557/pimr.2021.0027 ◽

2021 ◽

Vol 17 (2) ◽

pp. 173-175

Author(s):

Shalini Ramasamy ◽

◽

Jeyasakthy Saniasiaya ◽

Zainal Azmi Zainal Abidin ◽

◽

...

Keyword(s):

Differential Diagnosis ◽

Maxillary Sinus ◽

Young Woman ◽

Cell Formation ◽

Sinus Surgery ◽

Foreign Body Giant Cell ◽

Cholesterol Granuloma ◽

Rare Presentation ◽

Nasal Mass ◽

Giant Cell Formation

Aim of the study: Cholesterol granuloma is a histological entity which consists of granulation tissue in which a large quantity of cholesterol crystals provoke foreign body giant cell formation. Cholesterol granulomas are often found in the middle ear with rare presentation in the paranasal sinus. We would like to highlight the diagnostic challenges and the management of maxillary sinus cholesterol granuloma in a young woman presenting as a unilateral nasal mass. Case study: We report a young woman with cholesterol granuloma of maxillary sinus who initially presented with unilateral nasal obstruction. Rigid nasoendoscopy and imaging were suggestive of an antrochoanal polyp. Ipsilateral functional endoscopic sinus surgery was done successfully. Conclusion: Albeit rare, cholesterol granuloma ought to be considered a differential diagnosis in a sinonasal tumour. This case report highlights the rare presentation of maxillary sinus cholesterol granuloma which ought to be considered a differential diagnosis of a unilateral nasal mass.

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Chronic myeloid leukaemia manifesting as a gynecological emergency in a young woman

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20173504 ◽

2017 ◽

Vol 6 (8) ◽

pp. 3655

Author(s):

Vishnupriya Padmanabhan ◽

Mohamed M. Shahin ◽

Karim Abdallah

Keyword(s):

Bone Marrow ◽

Chronic Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Young Woman ◽

Rare Presentation ◽

Abdominal Bleeding ◽

Life Threatening ◽

Laboratory Investigations ◽

The Uk ◽

Obvious Source

Chronic Myeloid Leukaemia (CML) is a form of blood cancer that is characterized by unregulated growth of Myeloid cells within the bone marrow. Idiopathic Spontaneous Intraperitoneal Haemorrhage (ISIH) is a rare life-threatening presentation. Case report of a young woman who presented to the emergency department with evidence of intra-abdominal bleeding. thought to be of gynaecological origin. No obvious source for the bleeding could be identified intra-operatively. Laboratory investigations showed evidence of Leukaemia which was confirmed on bone marrow biopsy. CML represents 8% of leukaemia in the UK. Despite being a rare presentation, ISIH should be considered as a possible differential diagnosis for those patients when presenting with evidence of acute abdomen.

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PRIMARY LEIOMYOSARCOMA OF URINARY BLADDER- A RARE PRESENTATION IN POSTPARTUM PERIOD

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2016/1158 ◽

2016 ◽

Vol 3 (101) ◽

pp. 5596-5599

Author(s):

Sauda V. M ◽

Ashida M Krishnan

Keyword(s):

Urinary Bladder ◽

Postpartum Period ◽

Rare Presentation ◽

Primary Leiomyosarcoma

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A rare case of masseter muscle cysticercosis in a young female patient managed conservatively

Asian Pacific Journal of Health Sciences ◽

10.21276/apjhs.2020.7.3.4 ◽

2020 ◽

Vol 7 (3) ◽

pp. 15-17

Author(s):

Hardik Dodia ◽

Karnadev Solanki ◽

Bhaumik Shah

Keyword(s):

Young Woman ◽

Female Patient ◽

Clinical Examination ◽

Conservative Management ◽

Masseter Muscle ◽

Rare Case ◽

Taenia Solium ◽

Young Female ◽

Rare Presentation ◽

Cheek Swelling

Cysticercosis is caused by Taenia solium larvae infestation. Isolated oral cysticercosis is a very rare presentation of this disease. Here is a case of masseter cysticercosis in a young woman who presented with painful cheek swelling. Diagnosis is confirmed with history, clinical examination and MRI. Luckily patient got cured with conservative management.

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