Oxadiazole moiety, which is one of the heterocyclic aromatic groups of the azole family;
with the molecular formula C2H2N2O, exists in four isomeric form; out of which, 1,2,4-oxadiazole;
1,2,5-oxadiazole and 1,3,4-oxadiazole are common isomers. The stable isomeric forms of oxadiazoles
are observed in a variety of pharmaceutical important potent drugs including raltegravir, butalamine,
fasiplon, oxolamine and pleconaril. An attempt has been made to emphasize the chemistry and pharmacology
associated with oxadiazole and its derivatives. A number of oxadiazole derivatives are very
popular and common in use as potential therapeutic agents. However, a number of researchers are
working and have worked to find out more synthetic analogues for anticancer and antifungal, anti-HIV
agents using biological and in-silico models.