scholarly journals Morphological study of surgically induced open neural tube defects in chick embryos--postoperative 24 hours

1994 ◽  
Vol 9 (2) ◽  
pp. 116 ◽  
Author(s):  
Heon You ◽  
Ki Bum Sim ◽  
Kyu Chang Wang ◽  
Dong Gyu Kim ◽  
Hyun Jib Kim
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Morphological Study ◽  
Chick Embryos ◽  
Surgically Induced

Morphological study of surgically induced open neural tube defect in old (14 and 21 days) chick embryos

1995 ◽  
Vol 192 (1) ◽  
pp. 61-64 ◽  
Author(s):  
Ki-Bum Sim ◽  
Byung-Kyu Cho ◽  
Je G. Chi ◽  
Kyu-Chang Wang
Keyword(s):  
Neural Tube ◽  
Neural Tube Defect ◽  
Morphological Study ◽  
Chick Embryos ◽  
Surgically Induced

Chronological changes of re-closure capacity in surgically induced spinal open neural tube defects of chick embryos

2000 ◽  
Vol 292 (3) ◽  
pp. 151-154 ◽  
Author(s):  
Ki-Bum Sim ◽  
Byung-Kyu Cho ◽  
Yun Jin Lee ◽  
Myung Sook Lee ◽  
Kyu-Chang Wang
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Chick Embryos ◽  
Surgically Induced

Further studies on neural tube defects caused by concanavalin A in early chick embryos

1976 ◽  
Vol 32 (8) ◽  
pp. 1050-1052 ◽  
Author(s):  
H. Lee ◽  
R. G. Nagele ◽  
G. W. Kalmus
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Concanavalin A ◽  
Chick Embryos

Concanavalin A-induced Open Neural Tube Defects in Chick Embryos

1996 ◽  
Vol 36 (10) ◽  
pp. 691-697 ◽  
Author(s):  
Takayuki INAGAKI ◽  
Kyu-Chang WANG ◽  
Russell G. HIGBEE ◽  
David G. MCLONE ◽  
Paul A. KNEPPER
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Concanavalin A ◽  
Chick Embryos

Is the re-closure of surgically induced open neural tube defect the repetition of primary neurulation? An experimental study with chick embryos

2001 ◽  
Vol 307 (2) ◽  
pp. 69-72 ◽  
Author(s):  
Sang Ki Chung ◽  
Ki Bum Sim ◽  
Byung-Kyu Cho ◽  
Seung-Kwan Hong ◽  
Kyu-Chang Wang
Keyword(s):  
Experimental Study ◽  
Neural Tube ◽  
Neural Tube Defect ◽  
Chick Embryos ◽  
Surgically Induced

scholarly journals Analysis of the effects of Streptomyces hyaluronidase on formation of the neural tube

Development ◽  
1983 ◽  
Vol 73 (1) ◽  
pp. 1-15
Author(s):  
Gary C. Schoenwolf ◽  
Marilyn Fisher
Keyword(s):  
Spinal Cord ◽  
Extracellular Matrix ◽  
Hyaluronic Acid ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Developmental Process ◽  
Chick Embryos ◽  
In Ovo ◽  
Dorsal Midline ◽  
Specific Protease

Chick embryos at stages 8 to 9 were treated in ovo with Streptomyces hyaluronidase (SH) to determine whether neurulation occurs normally in embryos depleted of hyaluronic acid, a major component of the extracellular matrix. Open neural tube defects occurred in 60–94 % (depending on the particular enzyme batch) of the embryos treated with SH and examined after an additional 24 h of incubation. Defects were confined mainly to the spinal cord. The neural folds underwent elevation in defective regions but failed to converge and fuse across the dorsal midline. The extracellular matrix of embryos treated with SH was depleted consistently, as determined with sections stained with Alcian blue. Control experiments were done to ensure that neural tube defects were not caused by non-specific protease contamination of SH, or by digestion products of hyaluronic acid. We propose several plausible and testable mechanisms through which the extracellular matrix might influence the complex developmental process of neurulation.

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