scholarly journals Sclerosing mucoepidermoid carcinoma: specific histologic variant or nonspecific morphologic pattern?

2011 ◽  
Vol 15 (2) ◽  
pp. 53-55 ◽  
Author(s):  
Fumio Ide ◽  
Norio Horie ◽  
Tetsuo Shimoyama ◽  
Ichiro Saito
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Sclerosing Mucoepidermoid Carcinoma

Sclerosing Mucoepidermoid Carcinoma of the Thyroid Gland With Eosinophilia

2015 ◽  
Vol 93 (10) ◽  
pp. e137-e138
Author(s):  
Rolando Orbeal ◽  
Jaime Jimeno ◽  
Gabriela Monroy ◽  
Francesc Badia ◽  
David Parés
Keyword(s):  
Thyroid Gland ◽  
Mucoepidermoid Carcinoma ◽  
Sclerosing Mucoepidermoid Carcinoma

Sclerosing Mucoepidermoid Carcinoma of the Parotid Gland

2004 ◽  
Vol 128 (9) ◽  
pp. 1046-1049
Author(s):  
Oluwole Fadare ◽  
Denise Hileeto ◽  
Yves L. Gruddin ◽  
M. Rajan Mariappan
Keyword(s):  
Parotid Gland ◽  
Mucoepidermoid Carcinoma ◽  
Inflammatory Infiltrate ◽  
Plasma Cells ◽  
Relevant Literature ◽  
Primary Malignancy ◽  
Mechanisms Of Formation ◽  
Diagnostic Difficulties ◽  
Reactive Fibrosis ◽  
Sclerosing Mucoepidermoid Carcinoma

Abstract Although mucoepidermoid carcinoma is the most common primary malignancy of the salivary glands, the sclerosing morphologic variant of this tumor is extremely rare, with only 6 reported cases. As its name suggests, sclerosing mucoepidermoid carcinoma is characterized by an intense central sclerosis that occupies the entirety of an otherwise typical tumor, frequently with an inflammatory infiltrate of plasma cells, eosinophils, and/or lymphocytes at its peripheral regions. The sclerosis associated with these tumors may obscure their typical morphologic features and result in diagnostic difficulties. Tumor infarction and extravasation of mucin eventuating in reactive fibrosis are 2 mechanisms of formation that have been suggested as underlying this morphologic variant. We describe herein another case of sclerosing mucoepidermoid carcinoma that was diagnosed in a 44-year-old woman and review the relevant literature. Morphologic evidence in support of the mucin extravasation hypothesis was identified, as small pools of mucin were present throughout the tumor. However, there was no concentration of the mucin pools near the areas with the most viable tumor cells, which would have provided evidence for a temporal sequence that eventuates in lack of mucin in the most sclerotic regions.

Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: demonstrating the natural progression of a rare and misunderstood disease

2021 ◽  
Vol 14 (7) ◽  
pp. e241086
Author(s):  
Joseph Salem ◽  
Eamon Shamil ◽  
Lorrette Ffolkes ◽  
Enyinnaya Ofo
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Natural Progression ◽  
Sclerosing Mucoepidermoid Carcinoma

Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid in a 46-year-old woman.

Sclerosing mucoepidermoid carcinoma of the parotid gland

2006 ◽  
Vol 263 (10) ◽  
pp. 955-959 ◽  
Author(s):  
S. Brett Heavner ◽  
Rajal B. Shah ◽  
Jeffrey S. Moyer
Keyword(s):  
Parotid Gland ◽  
Mucoepidermoid Carcinoma ◽  
Sclerosing Mucoepidermoid Carcinoma

scholarly journals The Cytomorphologic Features of Sclerosing Mucoepidermoid Carcinoma of the Thyroid Gland With Eosinophilia

1998 ◽  
Vol 109 (3) ◽  
pp. 294-301 ◽  
Author(s):  
Kim R. Geisinger ◽  
Craig H. Steffee ◽  
Robert S McGee ◽  
Ralph D. Woodruff ◽  
David H. Buss
Keyword(s):  
Thyroid Gland ◽  
Mucoepidermoid Carcinoma ◽  
Sclerosing Mucoepidermoid Carcinoma
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