scholarly journals Drug-Induced Cough

2020 ◽  
pp. S81-S92 ◽  
Author(s):  
J. Shim ◽  
W.-J. Song ◽  
A.H. Morice

Since the recognition of angiotensin-converting enzyme inhibitors (ACEIs)-induced cough, drug has been considered as a potential cause of chronic cough. This review presents recent knowledge on drug-induced coughs in patients with chronic cough. The focus is placed on ACEIs, for which there are a multitude of studies documenting their associations with cough. Additional drugs are discussed for which there are reports of cough as a side effect of treatment, and the potential mechanisms of these effects are discussed.

2018 ◽  
Vol 74 (4) ◽  
pp. 277-281 ◽  
Author(s):  
Laurent Davin ◽  
Patrick Marechal ◽  
Patrizio Lancellotti ◽  
Christophe Martinez ◽  
Luc Pierard ◽  
...  

1994 ◽  
Vol 108 (8) ◽  
pp. 696-698 ◽  
Author(s):  
J. P. M. Pracy ◽  
J. A. McGlashan ◽  
R. M. Walsh ◽  
M. J. Gleeson

AbstractAngioedema secondary to angiotensin-converting enzyme (ACE) inhibitors is rare, but it is a side effect which is likely to be seen more frequently because of the increased use of these drugs to treat cardiac failure and hypertension. Presentation is variable and the diagnosis may go unrecognized for many months or years. The cases reported illustrate problems both in the diagnosis and management of this life-threatening condition.


Author(s):  
Rodrigo Cartin-Ceba

Cough is one of the most common reasons for outpatient medical consultation. Cough can be classified according to duration as acute (<3 weeks), subacute (3-8 weeks), and chronic (>8 weeks). Acute cough is usually related to an infectious cause, and symptomatic management usually suffices. Chronic cough, in contrast, is mainly related to postnasal drip, asthma, or gastroeseophageal reflux disease. Angiotensin-converting enzyme inhibitors have been implicated in up to 10% of patients with chronic cough.


2011 ◽  
Vol 68 (4) ◽  
pp. 372-376 ◽  
Author(s):  
Slobodan Jankovic ◽  
Srdjan Stefanovic

Introduction. Angiotensin-converting enzyme inhibitors are leading cause of drug-induced angioedema, with incidence of 0.1 to 0.2%. The angioedema is not of immune nature; in predisposed individuals it is caused by accumulation of vasoactive mediators due to reduced activity of angiotensinconverting enzyme. Case report. We presented a 63-year old male patient suffering from hypertension and chronic obstructive pulmonary disease, who had developed two episodes of angioedema during a 5-year long therapy with enalapril. The first episode happened after three, and the second after five years of the therapy. On both occasions, the patient was admitted to the hospital and tracheotomy was avoided in the last moment. Conclusion. Long-term therapy with angiotensin-converting enzyme inhibitors could be associated with delayed angioedema, especially in patients with inflammation of airways caused by infection or chronic irritation.


2016 ◽  
Vol 4 (16) ◽  
pp. 67
Author(s):  
Kenneth Iwuji ◽  
Hezekiah Sobamowo ◽  
James Tarbox ◽  
Rose Egbe

Angiotensin-converting enzyme (ACE) inhibitors are the leading cause of drug-induced angioedema in the United States because these drugs are widely prescribed for several common medical disorders. Angiotensin-converting enzyme inhibitors cause angioedema in 0.1 to 0.7 percent of recipients. When prescribing ACE-inhibitors to patients, angioedema should always be considered as a potential adverse reaction during treatment.


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