Evaluation of the efficacy and patient satisfaction of the intracavernosal alprostadil in the treatment of erectile dysfunction following robot-assisted radical prostatectomy

Objective: Erectile dysfunction (ED) following robot-assisted radical prostatectomy (RARP) is an important problem. The purpose of this study was to evaluate the effectiveness of and patient satisfaction with intracavernosal alprostadil used in the treatment of ED. Material and Methods: Patients using intracavernosal alprostadil in the treatment of ED following RARP were assessed retrospectively. Patients’ demographic characteristics, pre- and postoperative International Index of Erectile Function (IIEF) scores, and general satisfaction evaluated using questions 13 and 14 of the IIEF form were all recorded. Complications developing during treatment, dosages used, and reasons for discontinuation were investigated. Results: Thirty-four patients with a mean age of 61.73±5.80 years were included in the study. Preoperative ED was determined in 52.9% (n=18) of patients. The mean IEFF of the patients who used preoperative, postoperative 1st month, postoperative 3 months after tadalafil use and intracavernosal alprostadil was 20.64 ± 3.46, 15.08 ± 2.09, 15.32 ± 2.18, 26.67 ± 2.30, respectively. The mean length of use of intracavernosal alprostadil was 8.20±2.48 months, and full erection was achieved in 70.58% of patients. Hematoma associated with intracavernosal alprostadil use developed in 2.9% of patients, ecchymosis in 8.8%, and pain in 8.8%. In addition, 73.5% of patients continued to take their medication during the follow-up process. Patients’ general satisfaction following alprostadil therapy was statistically significantly high. Conclusion: Intracavernosal alprostadil therapy following RARP represents a good therapeutic option due to its high success in achieving full erection, low complication rates, and high patient satisfaction. Keywords: erectile dysfunction, Alprostadil, robot-assisted radical prostatectomy

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Outcomes and Postoperative Complications of Robot-Assisted Laparoscopic Hysterosacropexy: Initial Experience

Urologia Internationalis ◽

10.1159/000371726 ◽

2015 ◽

Vol 95 (1) ◽

pp. 44-49 ◽

Cited By ~ 1

Author(s):

Maria Angela Cerruto ◽

Carolina D'Elia ◽

Francesca Maria Cavicchioli ◽

Stefano Cavalleri ◽

Matteo Balzarro ◽

...

Keyword(s):

Uterine Prolapse ◽

Pelvic Organ ◽

Consecutive Series ◽

Complication Rates ◽

Early Complications ◽

Robot Assisted ◽

Female Patients ◽

The Mean ◽

Record Review

Background: Pelvic organ prolapse is a common condition, affecting about 50% of women with children. The aim of our study was to evaluate results and complication rates in a consecutive series of female patients undergoing robot-assisted laparoscopic hysterosacropexy (RALHSP). Materials and Methods: We performed a medical record review of female patients with uterine prolapse who had consecutively undergone RALHSP from February 2010 to 2013 at our department. Results: Fifteen patients were included in the analysis. All patients had uterine prolapse stage ≥II and urodynamic stress urinary incontinence. The mean age was 58.26 years. According to the Clavien-Dindo system, 4 out of 15 patients (26.6%) had grade 1 early complications and 1 patient had a grade 2 complication. At a median follow-up of 36 months, there was a significant prolapse relapse rate of 20% (3/15). Conclusion: In our hands RALHSP is easy to perform, with satisfying mid-term outcomes and a low complication rate.

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Erratum: Acknowledgments. The Efficacy and Safety of Tadalafil 5 mg Once Daily in the Treatment of Erectile Dysfunction After Robot-Assisted Laparoscopic Radical Prostatectomy: 1-Year Follow-up

Korean Journal of Urology ◽

10.4111/kju.2014.55.3.226 ◽

2014 ◽

Vol 55 (3) ◽

pp. 226 ◽

Cited By ~ 1

Author(s):

Young Eun Seo ◽

Soo Dong Kim ◽

Tae Hyo Kim ◽

Gyung Tak Sung

Keyword(s):

Erectile Dysfunction ◽

Radical Prostatectomy ◽

Laparoscopic Radical Prostatectomy ◽

Efficacy And Safety ◽

Robot Assisted ◽

Once Daily

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Re: Efficacy and Safety of Tadalafil 5 mg Once Daily for the Treatment of Erectile Dysfunction after Robot-Assisted Laparoscopic Radical Prostatectomy: A 2-Year Follow-up

The Journal of Urology ◽

10.1016/j.juro.2018.05.112 ◽

2018 ◽

Vol 200 (3) ◽

pp. 481-481

Author(s):

Allen D. Seftel

Keyword(s):

Erectile Dysfunction ◽

Radical Prostatectomy ◽

Laparoscopic Radical Prostatectomy ◽

Efficacy And Safety ◽

Robot Assisted ◽

Once Daily

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The Efficacy and Safety of Tadalafil 5 mg Once Daily in the Treatment of Erectile Dysfunction After Robot-Assisted Laparoscopic Radical Prostatectomy: 1-Year Follow-up

Korean Journal of Urology ◽

10.4111/kju.2014.55.2.112 ◽

2014 ◽

Vol 55 (2) ◽

pp. 112 ◽

Cited By ~ 8

Author(s):

Young Eun Seo ◽

Soo Dong Kim ◽

Tae Hyo Kim ◽

Gyung Tak Sung

Keyword(s):

Erectile Dysfunction ◽

Radical Prostatectomy ◽

Laparoscopic Radical Prostatectomy ◽

Efficacy And Safety ◽

Robot Assisted ◽

Once Daily

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Efficacy and Safety of Tadalafil 5 mg Once Daily for the Treatment of Erectile Dysfunction After Robot-Assisted Laparoscopic Radical Prostatectomy: A 2-Year Follow-Up

Sexual Medicine ◽

10.1016/j.esxm.2017.12.005 ◽

2018 ◽

Vol 6 (2) ◽

pp. 108-114 ◽

Cited By ~ 4

Author(s):

Soodong Kim ◽

Gyung Tak Sung

Keyword(s):

Erectile Dysfunction ◽

Radical Prostatectomy ◽

Laparoscopic Radical Prostatectomy ◽

Efficacy And Safety ◽

Robot Assisted ◽

Once Daily

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Same Day Discharge versus Inpatient Surgery for Robot-Assisted Radical Prostatectomy: A Comparative Study

Journal of Clinical Medicine ◽

10.3390/jcm10040661 ◽

2021 ◽

Vol 10 (4) ◽

pp. 661

Author(s):

Razvan George Rahota ◽

Ambroise Salin ◽

Jean Romain Gautier ◽

Christophe Almeras ◽

Guillaume Loison ◽

...

Keyword(s):

Lymph Node ◽

Radical Prostatectomy ◽

Comparative Study ◽

Lymph Node Dissection ◽

Perioperative Outcomes ◽

Complication Rates ◽

Node Dissection ◽

Robot Assisted ◽

Same Day Discharge

(1) Background: no study has compared outcomes of same day discharge (SDD) versus inpatient robot-assisted radical prostatectomy (RARP) in homogenous cohorts. Our aim was to compare perioperative outcomes and urinary continence recovery between SDD and inpatient RARP in contemporary, comparable patients. (2) Methods: we included consecutive patients undergoing RARP between 2018 and 2020 (n = 376). Only patients eligible for SDD (no oral anticoagulant, distance home-hospital <150 km) and having >6-month follow-up were included (n = 180). All patients underwent RARP with or without lymph node dissection. Comparisons were performed between SDD (n = 42) and inpatient RARP (n = 138). Primary outcomes were 90-day complication and readmission rates and continence rates at 1 and 6 months. (3) Results: median patient age was 66.7 years. Median duration of surgery and blood loss was 134 min and 200 mL, respectively. Lymph node dissection and nerve-sparing procedures were performed in 76.7% and 82.2% of cases, respectively. Median follow-up was 19.5 months. No difference was seen regarding patient features, peri-operative outcomes, and pathology parameters between both groups. The proportion of SDD RARP was stable over time (23.5%). The 90-day unplanned visits, readmission and complication rates were 9.5%, 7.1%, and 19.0% in SDD patients versus 14.5% (p = 0.407), 10.1% (p = 0.560), 28.3% (p = 0.234) for inpatient RARP, respectively. Trends favoring SDD were not statistically significant. Continence rates at 1-(p = 0.589) and 6-months (p = 0.674) were comparable between SDD and inpatient RARP. The main limitation was the lack of randomization. (4) Conclusions: this multi-surgeon comparative study confirms the safety of routine SDD RARP in terms of perioperative and functional outcomes. Trends favoring SDD in terms of complications, emergency visits and readmission have to be confirmed.

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Robot-assisted laparoscopic partial nephrectomy: Early single Canadian institution experience

Canadian Urological Association Journal ◽

10.5489/cuaj.753 ◽

2013 ◽

Vol 7 (9-10) ◽

pp. 348 ◽

Cited By ~ 9

Author(s):

Guillaume Ploussard ◽

Richard Haddad ◽

Evan Kovac ◽

Patrick Richard ◽

Maurice Anidjar ◽

...

Keyword(s):

Renal Function ◽

Partial Nephrectomy ◽

Tumour Size ◽

Admission Rate ◽

Complication Rates ◽

Robot Assisted ◽

Nephrometry Score ◽

Surgeon Experience ◽

The Mean

Background: Although robot-assisted partial nephrectomy (RALPN) has been increasingly adopted, open procedures continue to be the reference nephron-sparing technique. We describe our initial surgical outcomes of RALPN in our single institution robotic program.Methods: Between January 2011 and February 2013, 65 consecutive patients underwent a RALPN by 2 surgeons. Preoperative characteristics, including the R.E.N.A.L. nephrometry score, perioperative parameters, and postoperative course, including renal function, were assessed from a retrospective database. The mean follow-up was 12 months.Results: The mean age was 60.2 years and the mean tumour size was 3.9 cm. According to the R.E.N.A.L. nephrometry score, the tumours were classified moderately and highly complex tumours in 51% and 18.5% of cases, respectively. Median warm ischemia time (WIT) was 21 minutes. Factors associated with WIT were R.E.N.A.L. nephrometry score, tumour size, complication rates and surgeon experience. No conversion or grade 4 to 5 complications were reported. The mean hospital stay was 3 days. The overall complication rate was 24.6% (re-admission rate 7.7%), and decreased to 12% after 20 cases. After these initial 20 cases, a trifecta rate (no margins, preserved renal function, no complications) of 64.3% was achieved in moderately and highly complex tumours. The mean change in estimated glomerular filtration rate was 6.7 mL/min without severe postoperative renal failure.Interpretation: RALPN is a safe and feasible procedure with low specific morbidity, even in moderately or highly complex renal masses. The WIT depends on tumour characteristics, mainly determined by the R.E.N.A.L. nephrometry score and is improved by surgeon experience. Longer follow-up is needed to assess the oncologic mid-term safety of the procedure.

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25: Quality of Life Outcomes after Robot Assisted Laparoscopic Radical Prostatectomy: 3 Year Follow-Up

The Journal of Urology ◽

10.1016/s0022-5347(18)34290-3 ◽

2005 ◽

Vol 173 (4S) ◽

pp. 7-7

Author(s):

Caner Dinlenc ◽

Adam Berman ◽

Joseph Wagner

Keyword(s):

Quality Of Life ◽

Radical Prostatectomy ◽

Laparoscopic Radical Prostatectomy ◽

Life Outcomes ◽

Robot Assisted ◽

Quality Of Life Outcomes

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Hybrid Endovascular Repair of Thoracoabdominal Aorta: Early Results

The Heart Surgery Forum ◽

10.1532/hsf98.2014315 ◽

2014 ◽

Vol 17 (3) ◽

pp. 146

Author(s):

Osman Tansel Darcin ◽

Mehmet Kalender ◽

Ayse Gul Kunt ◽

Okay Guven Karaca ◽

Ata Niyazi Ecevit ◽

...

Keyword(s):

Endovascular Repair ◽

Therapeutic Option ◽

Complete Recovery ◽

Aortic Aneurysms ◽

Thoracoabdominal Aorta ◽

Mortality And Morbidity ◽

Early Results ◽

The Mean ◽

Procedural Success

Background: Thoracoabdominal aortic aneurysms (TAAA) present a significant clinical challenge, as they are complex and require invasive surgery. In an attempt to prevent considerably high mortality and morbidity in open repair, hybrid endovascular repair has been developed by many authors. In this study, we evaluated the early-term results obtained from this procedure.Methods: From November 2010 to February 2013, we performed thoracoabdominal hybrid aortic repair in 18 patients. The mean age was 68 years (12 men, 6 women). All of the patients had significant comorbidities. Follow-up computed tomography (CT) scans were performed at 1 week, 3 months, 6 months, and annually thereafter.Results: All patients were operated on in a staged procedure and stent graft deployment was achieved. Procedural success was achieved in all cases. All patients were discharged with complete recovery. No endoleaks weres detected in further CT examination.Conclusion: Our results suggests that hybrid debranching and endovascular repair of extensive thoracoabdominal aneurysms represents a suitable therapeutic option to reduce the morbidity and mortality of TAAA repair, particularly in those typically considered at high risk for standard repair.

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